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Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
Edition 2ISBN: 9780130819086Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
Edition 2ISBN: 9780130819086 Exercise 7
You must design an operating strategy to allow an E. coli fermentation to achieve a high cell
density
in a fed-batch system. You have access to an off-gas analyzer that will mea-
sure the pCO₂ in the exit gas. The glucose concentration must be less than 100 mg/l to avoid
the formation of acetate and other inhibitory products. Develop an approach to control the
glucose feed rate so as to maintain the glucose level at
what equations would
you use and what assumptions would you make?
density
in a fed-batch system. You have access to an off-gas analyzer that will mea-sure the pCO₂ in the exit gas. The glucose concentration must be less than 100 mg/l to avoid
the formation of acetate and other inhibitory products. Develop an approach to control the
glucose feed rate so as to maintain the glucose level at
what equations wouldyou use and what assumptions would you make?
Explanation
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The operating strategy can be made to us...
Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
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