Question 1

Which statement(s)about liberation of drugs is/are true? (Select all that apply.)

Accepted Answer

A)  A drug must be dissolved in body fluids before it can be absorbed into body tissues. 
B)  A solid drug taken orally must disintegrate and dissolve in GI fluids to allow for absorption into the bloodstream for transport to the site of action. 
C)  The process of converting the drug into a soluble form can be controlled to a certain degree by the dosage form. 
D)  Converting the drug to a soluble form can be influenced by administering the drug with or without food in the patient's stomach. 
E)  Elixirs take longer to be liberated from the dosage form. 
A)  A drug must be dissolved in body fluids before it can be absorbed into body tissues. 
B)  A solid drug taken orally must disintegrate and dissolve in GI fluids to allow for absorption into the bloodstream for transport to the site of action. 
C)  The process of converting the drug into a soluble form can be controlled to a certain degree by the dosage form. 
D)  Converting the drug to a soluble form can be influenced by administering the drug with or without food in the patient's stomach. 
E)  Elixirs take longer to be liberated from the dosage form. A,B,C,D

Question 2

What do drug blood levels indicate?

Accepted Answer

A)  They confirm if the patient is taking a generic form of a drug. 
B)  They determine if the patient has sufficient body fat to metabolize the drug. 
C)  They verify if the patient is taking someone else's medications. 
D)  They determine if the amount of drug in the body is in a therapeutic range. 
A)  They confirm if the patient is taking a generic form of a drug. 
B)  They determine if the patient has sufficient body fat to metabolize the drug. 
C)  They verify if the patient is taking someone else's medications. 
D)  They determine if the amount of drug in the body is in a therapeutic range. D

Question 3

The nurse administers an initial dose of a steroid to a patient with asthma.Thirty minutes after administration,the nurse finds the patient agitated and stating that "everyone is out to get me." What is the term for this unusual reaction?

Accepted Answer

A)  Desired action 
B)  Adverse effect 
C)  Idiosyncratic reaction 
D)  Allergic reaction 
A)  Desired action 
B)  Adverse effect 
C)  Idiosyncratic reaction 
D)  Allergic reaction C

Question 4

Which route(s)enable(s)drug absorption more rapidly than the subcut route? (Select all that apply.)

Accepted Answer

A)  IV route 
B)  IM route 
C)  Inhalation/sublingual 
D)  Intradermal route 
E)  Enteral route 
A)  IV route 
B)  IM route 
C)  Inhalation/sublingual 
D)  Intradermal route 
E)  Enteral route

Question 5

The nurse administers 50 mg of a drug at 6:00 AM that has a half-life of 8 hours.What time will it be when 25 mg of the drug has been eliminated from the body?

Accepted Answer

A)  8:00 AM 
B)  11:00 AM 
C)  2:00 PM 
D)  6:00 PM 
A)  8:00 AM 
B)  11:00 AM 
C)  2:00 PM 
D)  6:00 PM

Question 6

Which are routes of drug excretion? (Select all that apply.)

Accepted Answer

A)  GI tract,feces 
B)  Genitourinary (GU)tract,urine 
C)  Lymphatic system 
D)  Circulatory system,blood/plasma 
E)  Respiratory system,exhalation 
A)  GI tract,feces 
B)  Genitourinary (GU)tract,urine 
C)  Lymphatic system 
D)  Circulatory system,blood/plasma 
E)  Respiratory system,exhalation

Question 7

The nurse recognizes that which factor(s)would contribute to digoxin toxicity in a 92-year-old patient? (Select all that apply.)

Accepted Answer

A)  Taking the medication with meals 
B)  Prolonged half-life of the drug digoxin 
C)  Impaired renal function 
D)  Diminished mental capacity 
A)  Taking the medication with meals 
B)  Prolonged half-life of the drug digoxin 
C)  Impaired renal function 
D)  Diminished mental capacity

Question 8

What occurs when two drugs compete for the same receptor site,resulting in increased activity of the first drug?

Accepted Answer

A)  Desired action 
B)  Synergistic effect 
C)  Carcinogenicity 
D)  Displacement 
A)  Desired action 
B)  Synergistic effect 
C)  Carcinogenicity 
D)  Displacement

Question 9

The nurse assesses hives in a patient started on a new medication.What is the nurse's priority action?

Accepted Answer

A)  Notify physician of allergic reaction. 
B)  Notify physician of idiosyncratic reaction. 
C)  Notify physician of potential teratogenicity. 
D)  Notify physician of potential tolerance. 
A)  Notify physician of allergic reaction. 
B)  Notify physician of idiosyncratic reaction. 
C)  Notify physician of potential teratogenicity. 
D)  Notify physician of potential tolerance.

Question 10

What is the process by which a drug is transported by circulating body fluids to receptor sites?

Accepted Answer

A)  Osmosis 
B)  Distribution 
C)  Absorption 
D)  Biotransformation 
A)  Osmosis 
B)  Distribution 
C)  Absorption 
D)  Biotransformation

Question 11

A patient developed hives and itching after receiving a drug for the first time.Which instruction by the nurse is accurate?

Accepted Answer

A)  Stop the medication and encourage the patient to wear a medical alert bracelet that explains the allergy. 
B)  Explain to the patient that these are signs and symptoms of an anaphylactic reaction. 
C)  Emphasize to the patient the importance to inform medical personnel that in the future a lower dosage of this drug is necessary. 
D)  Instruct the patient that it would be safe to take the drug again because this instance was a mild reaction. 
A)  Stop the medication and encourage the patient to wear a medical alert bracelet that explains the allergy. 
B)  Explain to the patient that these are signs and symptoms of an anaphylactic reaction. 
C)  Emphasize to the patient the importance to inform medical personnel that in the future a lower dosage of this drug is necessary. 
D)  Instruct the patient that it would be safe to take the drug again because this instance was a mild reaction.

Question 12

Which factor(s)affect(s)drug actions? (Select all that apply.)

Accepted Answer

A)  Teratogenicity 
B)  Age 
C)  Body weight 
D)  Metabolic rate 
E)  Illness 
A)  Teratogenicity 
B)  Age 
C)  Body weight 
D)  Metabolic rate 
E)  Illness

Question 13

A physician's order indicates to administer a medication to the patient via the percutaneous route.The nurse can anticipate that the patient will receive this medication:

Accepted Answer

A)  intramuscularly. 
B)  subcutaneously. 
C)  topically. 
D)  rectally. 
A)  intramuscularly. 
B)  subcutaneously. 
C)  topically. 
D)  rectally.

Question 14

Which is the best description of when drug interactions occur?

Accepted Answer

A)  On administration of toxic dosages of a drug 
B)  On an increase in the pharmacodynamics of bound drugs 
C)  On the alteration of the effect of one drug by another drug 
D)  On increase of drug excretion 
A)  On administration of toxic dosages of a drug 
B)  On an increase in the pharmacodynamics of bound drugs 
C)  On the alteration of the effect of one drug by another drug 
D)  On increase of drug excretion

Question 15

The nurse assesses which blood level to determine the amount of circulating medication in a patient?

Accepted Answer

A)  Peak 
B)  Trough 
C)  Drug 
D)  Therapeutic 
A)  Peak 
B)  Trough 
C)  Drug 
D)  Therapeutic

Question 16

Which statement(s)about variables that influence drug action is/are true? (Select all that apply.)

Accepted Answer

A)  An older adult will require increased dosage of a drug to achieve the same therapeutic effect as that seen in a younger person. 
B)  Body weight can affect the therapeutic response of a medication. 
C)  Chronic smokers may metabolize drugs more rapidly than nonsmokers. 
D)  A patient's attitude and expectations affect the response to medication. 
E)  Reduced circulation causes drugs to absorb more rapidly. 
A)  An older adult will require increased dosage of a drug to achieve the same therapeutic effect as that seen in a younger person. 
B)  Body weight can affect the therapeutic response of a medication. 
C)  Chronic smokers may metabolize drugs more rapidly than nonsmokers. 
D)  A patient's attitude and expectations affect the response to medication. 
E)  Reduced circulation causes drugs to absorb more rapidly.

Question 17

When obtaining a patient's health history,which assessment data would the nurse identify as having the most effect on drug metabolism?

Accepted Answer

A)  History of liver disease 
B)  Intake of a vegetarian diet 
C)  Sedentary lifestyle 
D)  Teacher as an occupation 
A)  History of liver disease 
B)  Intake of a vegetarian diet 
C)  Sedentary lifestyle 
D)  Teacher as an occupation

Question 18

What will the nurse need to determine first in order to mix two drugs in the same syringe?

Accepted Answer

A)  Absorption rate of the drugs 
B)  Compatibility of the drugs 
C)  Drug blood level of each drug 
D)  Medication adverse effects 
A)  Absorption rate of the drugs 
B)  Compatibility of the drugs 
C)  Drug blood level of each drug 
D)  Medication adverse effects

Question 19

A nurse is preparing to administer tetracycline to a patient diagnosed with an infection.Which medication should not be administered with tetracycline?

Accepted Answer

A)  Ativan 
B)  Tylenol 
C)  Colace 
D)  Mylanta 
A)  Ativan 
B)  Tylenol 
C)  Colace 
D)  Mylanta

Exam 2: Basic Principles of Drug Action and Drug Interactions

Which statement(s)about liberation of drugs is/are true? (Select all that apply.)

What do drug blood levels indicate?

The nurse administers an initial dose of a steroid to a patient with asthma.Thirty minutes after administration,the nurse finds the patient agitated and stating that "everyone is out to get me." What is the term for this unusual reaction?

Which route(s)enable(s)drug absorption more rapidly than the subcut route? (Select all that apply.)

The nurse administers 50 mg of a drug at 6:00 AM that has a half-life of 8 hours.What time will it be when 25 mg of the drug has been eliminated from the body?

Which are routes of drug excretion? (Select all that apply.)

The nurse recognizes that which factor(s)would contribute to digoxin toxicity in a 92-year-old patient? (Select all that apply.)

What occurs when two drugs compete for the same receptor site,resulting in increased activity of the first drug?

The nurse assesses hives in a patient started on a new medication.What is the nurse's priority action?

What is the process by which a drug is transported by circulating body fluids to receptor sites?

A patient developed hives and itching after receiving a drug for the first time.Which instruction by the nurse is accurate?

Which factor(s)affect(s)drug actions? (Select all that apply.)

A physician's order indicates to administer a medication to the patient via the percutaneous route.The nurse can anticipate that the patient will receive this medication:

Which is the best description of when drug interactions occur?

The nurse assesses which blood level to determine the amount of circulating medication in a patient?

Which statement(s)about variables that influence drug action is/are true? (Select all that apply.)

When obtaining a patient's health history,which assessment data would the nurse identify as having the most effect on drug metabolism?

What will the nurse need to determine first in order to mix two drugs in the same syringe?

A nurse is preparing to administer tetracycline to a patient diagnosed with an infection.Which medication should not be administered with tetracycline?

Drug Definitions, standards, and Information Sources

Drug Action Across the Life Span

The Nursing Process and Pharmacology

Patient Education to Promote Health

Principles of Medication Administration and Medication Safety

Percutaneous Administration

Enteral Administration

Parenteral Administration: Safe Preparation of Parenteral Medications

Parenteral Administration: Intradermal, subcutaneous, and Intramuscular Routes

Parenteral Administration: Intravenous Route

Drugs Affecting the Autonomic Nervous System

Drugs Used for Sleep

Drugs Used to Treat Neurodegenerative Disorders

Drugs Used for Anxiety Disorders

Drugs Used for Depressive and Bipolar Disorders

Drugs Used for Psychoses

Drugs Used for Seizure Disorders

Drugs Used for Pain Management

Introduction to Cardiovascular Disease and Metabolic Syndrome

Drugs Used to Treat Dyslipidemias

Drugs Used to Treat Hypertension

Drugs Used to Treat Dysrhythmias

Drugs Used to Treat Angina Pectoris

Drugs Used to Treat Peripheral Vascular Disease

Drugs Used to Treat Thromboembolic Disorders

Drugs Used to Treat Heart Failure

Drugs Used for Diuresis

Drugs Used to Treat Upper Respiratory Disease

Drugs Used to Treat Lower Respiratory Disease

Drugs Used to Treat Oral Disorders

Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease

Drugs Used to Treat Nausea and Vomiting

Drugs Used to Treat Constipation and Diarrhea

Drugs Used to Treat Diabetes Mellitus

Drugs Used to Treat Thyroid Disease

Corticosteroids

Gonadal Hormones

Drugs Used in Obstetrics

Drugs Used in Mens and Womens Health

Drugs Used to Treat Disorders of the Urinary System

Drugs Used to Treat Glaucoma and Other Eye Disorders

Drugs Used to Treat Cancer

Drugs Used to Treat the Musculoskeletal System

Antimicrobial Agents

Nutrition

Herbal and Dietary Supplement Therapy

Substance Abuse

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