Exam 1: An Introduction to Drug Use

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Why do drug experts investigate the factor of cross-tolerance? Under what circumstances would cross-tolerance be a factor in the harms one or more drugs inflict on users?

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Drug experts investigate the factor of cross-tolerance because it can have significant implications for drug use and abuse. Cross-tolerance occurs when the tolerance to one drug also results in a tolerance to another drug, even if the second drug has not been used before. This means that individuals who have developed a tolerance to one drug may also have a reduced response to another drug, even if they have not used it previously.

Cross-tolerance can be a factor in the harms that one or more drugs inflict on users in several circumstances. For example, individuals who have developed a tolerance to one drug may be more likely to use higher doses of another drug in order to achieve the desired effects, increasing the risk of overdose and other negative consequences. Additionally, cross-tolerance can also contribute to the development of polydrug tolerance, where individuals develop a tolerance to multiple drugs simultaneously, leading to increased drug dependence and potential health risks.

Overall, understanding the factor of cross-tolerance is important for drug experts in order to better understand the potential risks and harms associated with drug use, and to develop effective strategies for harm reduction and treatment.

Which of the following drugs generates the most compulsive pattern of continued, abusive use in laboratory animals?

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C

The definition of the term "drug" that is central to this book is based on a substance's:

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Alcohol is the most widely used drug both globally and in the United States, and marijuana is the most popular and widely used illicit drug. Is the popularity of these drugs an accident of history, a function of their legal status, or inherent to the objective properties of these two drugs themselves? Justify your argument.

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Which of the following drugs generates the greatest immediate sensual appeal?

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Which drug type speeds up signals passing through the central nervous system (CNS)?

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Some drug effects take place over the long run; others are more short-term. Which of the following distinctions or dimensions is this difference relevant for?

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Which drug combination produces the most clear-cut synergistic effect?

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In this book, we are mainly interested in drug taking:

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It is virtually impossible to die of an overdose of:

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The author's position on drug use and drug abuse is that all:

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Years of Potential Life Lost (YPLL) is an important consideration when assessing the harm or damage that a drug inflicts on its users and the users' peers. Weigh the relative harm that tobacco and alcohol inflict, in the light of YPLL. Do the same for the legal drugs versus the illegal drugs. Does the factor of YPLL significantly change our previous estimates of the picture of drug harm?

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In all probability, the psychoactivity of drugs was discovered by humans when they:

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In the past, the classic model of drug addiction was used to explain why some users took drugs compulsively and abusively. More recently, drug researchers have used the dependence-reinforcement model to explain ongoing, abusive, compulsive drug abuse. How are these two models different, what phenomena do they help explain, which drug is each of them most relevant to, and why is the latter model a more powerful explanation for drug abuse?

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Not all drugs are addicting in the classic sense of the term. Which one of the following substances is not classically addicting?

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The psychoactive ingredient in marijuana is:

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What happens after heroin enters the body? It breaks down into:

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The chemical keys of THC fit into and bind with the organic structures that control:

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Consider why certain drugs are taken mainly or only in certain ways, knowing what you know about the drugs' properties and the factor of route of administration.

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Why is smoking the fastest, most efficient route of administration in generating drug effects-even faster and more efficient than IV administration? Why is oral administration such a slow means of administering drugs? Do these routes determine how dependency-producing drugs are used by each route? Why or why not?

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