Question 1

The apical ectodermal ridge runs in which direction in the developing limb bud?

Accepted Answer

A)  Antero-posterior 
B)  Dorso-ventral 
C)  Proximo-distal 
D)  Left-right 
A)  Antero-posterior 
B)  Dorso-ventral 
C)  Proximo-distal 
D)  Left-right B

Question 2

Which of the following intercellular signaling pathways directly controls the direction of knee and knuckle bending?

Accepted Answer

A)  FGF 
B)  Shh 
C)  Wnt 
D)  Notch 
A)  FGF 
B)  Shh 
C)  Wnt 
D)  Notch C

Question 3

Which of the following tissues signals to the overlying ectoderm in a vertebrate embryo to induce the lens placode?

Accepted Answer

A)  Surface ectoderm 
B)  Neural retina 
C)  Cornea 
D)  Optic vesicle 
A)  Surface ectoderm 
B)  Neural retina 
C)  Cornea 
D)  Optic vesicle D

Question 4

Which mechanism underlies the formation of separate digits?

Accepted Answer

A)  FGF induces apoptosis of interdigital cells 
B)  Lack of FGF induces necrosis of interdigital cells 
C)  BMP induces apoptosis of interdigital cells 
D)  Lack of BMP induces necrosis of interdigital cells 
A)  FGF induces apoptosis of interdigital cells 
B)  Lack of FGF induces necrosis of interdigital cells 
C)  BMP induces apoptosis of interdigital cells 
D)  Lack of BMP induces necrosis of interdigital cells

Question 5

Which of the following is synthesized along the antero-posterior wing boundary to act as a morphogen to cells in both compartments?

Accepted Answer

A)  Decapentaplegic (Dpp) 
B)  Spalt (Sal) 
C)  Brinker (Brk) 
D)  Optomotorblind (Omb) 
A)  Decapentaplegic (Dpp) 
B)  Spalt (Sal) 
C)  Brinker (Brk) 
D)  Optomotorblind (Omb)

Question 6

Which of the following refers to a chemical or infection that interferes with embryonic development, leading to defects in the animal?

Accepted Answer

A)  Teratogen 
B)  Mutagen 
C)  Morphogen 
D)  Carcinogen 
A)  Teratogen 
B)  Mutagen 
C)  Morphogen 
D)  Carcinogen

Question 7

Which of the following is not true of the pax6 gene?

Accepted Answer

A)  Loss of Pax6 function in humans leads to aniridia 
B)  Ectopic pax6 expression induces eye development in non-eye imaginal discs 
C)  Pax6 function is evolutionarily conserved 
D)  It encodes a intercellular signaling receptor 
A)  Loss of Pax6 function in humans leads to aniridia 
B)  Ectopic pax6 expression induces eye development in non-eye imaginal discs 
C)  Pax6 function is evolutionarily conserved 
D)  It encodes a intercellular signaling receptor

Question 8

What is the correct flow of interactions that determines proper positioning and outgrowth of the forelimb?

Accepted Answer

A)  Lateral plate - Hox - Tbx5 - FGF-10 - apical ectodermal ridge 
B)  Lateral plate - Tbx4 - Hox - FGF-10 - apical ectodermal ridge 
C)  Lateral plate - Hox - Tbx4 - FGF-10 - apical ectodermal ridge- 
D)  Lateral plate - Tbx5 - Hox - FGF-10 - apical ectodermal ridge 
A)  Lateral plate - Hox - Tbx5 - FGF-10 - apical ectodermal ridge 
B)  Lateral plate - Tbx4 - Hox - FGF-10 - apical ectodermal ridge 
C)  Lateral plate - Hox - Tbx4 - FGF-10 - apical ectodermal ridge- 
D)  Lateral plate - Tbx5 - Hox - FGF-10 - apical ectodermal ridge

Question 9

Which axis in the Drosophila wing is inherited through engrailed expression from the embryonic parasegment?

Accepted Answer

A)  Antero-posterior 
B)  Dorso-ventral 
C)  Proximo-distal 
D)  Left-right 
A)  Antero-posterior 
B)  Dorso-ventral 
C)  Proximo-distal 
D)  Left-right

Question 10

Which of the following intercellular signaling pathways directly controls the sequence of limb digits across the antero-posterior axis?

Accepted Answer

A)  FGF 
B)  Shh 
C)  Wnt 
D)  BMP 
A)  FGF 
B)  Shh 
C)  Wnt 
D)  BMP

The apical ectodermal ridge runs in which direction in the developing limb bud?

Which of the following intercellular signaling pathways directly controls the direction of knee and knuckle bending?

Which of the following tissues signals to the overlying ectoderm in a vertebrate embryo to induce the lens placode?

Which mechanism underlies the formation of separate digits?

Which of the following is synthesized along the antero-posterior wing boundary to act as a morphogen to cells in both compartments?

Which of the following refers to a chemical or infection that interferes with embryonic development, leading to defects in the animal?

Which of the following is not true of the pax6 gene?

What is the correct flow of interactions that determines proper positioning and outgrowth of the forelimb?

Which axis in the Drosophila wing is inherited through engrailed expression from the embryonic parasegment?

Which of the following intercellular signaling pathways directly controls the sequence of limb digits across the antero-posterior axis?

History and Basic Concepts

Drosophila Life Cycle and Development of the Body Plan

Vertebrate Life Cycles, Experimental Techniques Human Development

Laying Down the Vertebrate Body Plan: Xenopus and Zebrafish

Laying Down and Completing the Vertebrate Body Plan: Chick and Mouse

Morphogenesis: Change in Form in the Early Embryo

Cell Differentiation Stem Cells

Germ Cells, Fertilization Sex

Development of the Nervous System

Growth, Post-Embryonic Development and Regeneration

Plant Life Cycle and Development

Evolution and Development

Filters

Exam 10: Organogenesis

The apical ectodermal ridge runs in which direction in the developing limb bud?

Which of the following intercellular signaling pathways directly controls the direction of knee and knuckle bending?

Which of the following tissues signals to the overlying ectoderm in a vertebrate embryo to induce the lens placode?

Which mechanism underlies the formation of separate digits?

Which of the following is synthesized along the antero-posterior wing boundary to act as a morphogen to cells in both compartments?

Which of the following refers to a chemical or infection that interferes with embryonic development, leading to defects in the animal?

Which of the following is not true of the pax6 gene?

What is the correct flow of interactions that determines proper positioning and outgrowth of the forelimb?

Which axis in the Drosophila wing is inherited through engrailed expression from the embryonic parasegment?

Which of the following intercellular signaling pathways directly controls the sequence of limb digits across the antero-posterior axis?

History and Basic Concepts

Drosophila Life Cycle and Development of the Body Plan

Vertebrate Life Cycles, Experimental Techniques Human Development

Laying Down the Vertebrate Body Plan: Xenopus and Zebrafish

Laying Down and Completing the Vertebrate Body Plan: Chick and Mouse

Morphogenesis: Change in Form in the Early Embryo

Cell Differentiation Stem Cells

Germ Cells, Fertilization Sex

Development of the Nervous System

Growth, Post-Embryonic Development and Regeneration

Plant Life Cycle and Development

Evolution and Development

Filters