Question 1

Which of the following is a good serologic marker of hepatocellular carcinoma?

Accepted Answer

A)  Bilirubin 
B)  Human chorionic gonadotropin 
C)  Alpha-fetoprotein 
D)  Alpha1-antitrypsin 
E)  Alkaline phosphatase 
A)  Bilirubin 
B)  Human chorionic gonadotropin 
C)  Alpha-fetoprotein 
D)  Alpha1-antitrypsin 
E)  Alkaline phosphatase C

Question 2

In hemochromatosis the liver contains increased amounts of:

Accepted Answer

A)  Copper 
B)  Zinc 
C)  Iron 
D)  Selenium 
E)  Nickel 
A)  Copper 
B)  Zinc 
C)  Iron 
D)  Selenium 
E)  Nickel C

Question 3

In chronic liver failure there is a marked decrease of blood:

Accepted Answer

A)  Hemoglobin 
B)  Bilirubin 
C)  Immunoglobulin G 
D)  Immunoglobulin M 
E)  Albumin 
A)  Hemoglobin 
B)  Bilirubin 
C)  Immunoglobulin G 
D)  Immunoglobulin M 
E)  Albumin E

Question 4

Unconjugated hyperbilirubinemia is indicative of:

Accepted Answer

A)  Hemolytic jaundice 
B)  Viral hepatitis 
C)  Drug-induced hepatitis 
D)  Hepatic tumor 
E)  Extrahepatic biliary obstruction 
A)  Hemolytic jaundice 
B)  Viral hepatitis 
C)  Drug-induced hepatitis 
D)  Hepatic tumor 
E)  Extrahepatic biliary obstruction

Question 5

Which of the following hepatitis viruses is a DNA virus with a protein envelope that contains several distinct antigens,such as surface antigen?

Accepted Answer

A)  HAV 
B)  HBV 
C)  HCV 
D)  HDV 
E)  HEV 
A)  HAV 
B)  HBV 
C)  HCV 
D)  HDV 
E)  HEV

Question 6

All the following are major functions of the liver except:

Accepted Answer

A)  Excretory 
B)  Metabolic 
C)  Storage 
D)  Neuroendocrine 
E)  Synthetic 
A)  Excretory 
B)  Metabolic 
C)  Storage 
D)  Neuroendocrine 
E)  Synthetic

Question 7

The most common malignant tumor of the liver is:

Accepted Answer

A)  Hepatocellular carcinoma 
B)  Cholangiocellular carcinoma 
C)  Kupffer cell sarcoma 
D)  Carcinoid 
E)  Metastatic tumor from another site 
A)  Hepatocellular carcinoma 
B)  Cholangiocellular carcinoma 
C)  Kupffer cell sarcoma 
D)  Carcinoid 
E)  Metastatic tumor from another site

Question 8

Unconjugated bilirubin circulates in the blood bound to:

Accepted Answer

A)  Immunoglobulin G 
B)  Albumin 
C)  Haptoglobin 
D)  Transferrin 
E)  Ceruloplasmin 
A)  Immunoglobulin G 
B)  Albumin 
C)  Haptoglobin 
D)  Transferrin 
E)  Ceruloplasmin

Question 9

Gallbladder carcinoma is:

Accepted Answer

A)  More common in females than in males 
B)  More often squamous than adenocarcinoma 
C)  More often invading the intestine than the liver 
D)  More common in young people than in old people 
E)  More often accompanied by jaundice than carcinoma of the common bile duct 
A)  More common in females than in males 
B)  More often squamous than adenocarcinoma 
C)  More often invading the intestine than the liver 
D)  More common in young people than in old people 
E)  More often accompanied by jaundice than carcinoma of the common bile duct

Question 10

Which of the following hepatitis viruses is currently the most common cause of cirrhosis in the United States?

Accepted Answer

A)  HAV 
B)  HBV 
C)  HCV 
D)  HDV 
E)  HEV 
A)  HAV 
B)  HBV 
C)  HCV 
D)  HDV 
E)  HEV

Question 11

Which of the following serum enzymes is the most reliable marker of extrahepatic biliary obstruction?

Accepted Answer

A)  Alanine aminotransferase 
B)  Aspartate aminotransferase 
C)  Creatine kinase 
D)  Amylase 
E)  Alkaline phosphatase 
A)  Alanine aminotransferase 
B)  Aspartate aminotransferase 
C)  Creatine kinase 
D)  Amylase 
E)  Alkaline phosphatase

Question 12

Complications of cirrhosis include all the following except:

Accepted Answer

A)  Ascites 
B)  Splenomegaly 
C)  Esophageal varices 
D)  Hypoalbuminemia 
E)  Hypogammaglobulinemia 
A)  Ascites 
B)  Splenomegaly 
C)  Esophageal varices 
D)  Hypoalbuminemia 
E)  Hypogammaglobulinemia

Question 13

In Wilson's disease the serum contains decreased amounts of:

Accepted Answer

A)  Hemosiderin 
B)  Transferrin 
C)  Ferritin 
D)  Ceruloplasmin 
E)  Haptoglobin 
A)  Hemosiderin 
B)  Transferrin 
C)  Ferritin 
D)  Ceruloplasmin 
E)  Haptoglobin

Question 14

Which immunologic finding is most typical of primary biliary cirrhosis?

Accepted Answer

A)  Antinuclear antibodies 
B)  Antismooth muscle antibodies 
C)  Antimitochondrial antibodies 
D)  Antimicrosomal antibodies 
E)  Antinucleolar antibodies 
A)  Antinuclear antibodies 
B)  Antismooth muscle antibodies 
C)  Antimitochondrial antibodies 
D)  Antimicrosomal antibodies 
E)  Antinucleolar antibodies

Question 15

Which of the following is the most common cause of cirrhosis in childhood?

Accepted Answer

A)  Hepatitis A virus infection 
B)  Hepatitis D virus infection 
C)  Hemosiderosis 
D)  Alpha1-antitrypsin deficiency 
E)  Wilson's disease 
A)  Hepatitis A virus infection 
B)  Hepatitis D virus infection 
C)  Hemosiderosis 
D)  Alpha1-antitrypsin deficiency 
E)  Wilson's disease

Question 16

Primary sclerosing cholangitis affects primarily:

Accepted Answer

A)  Intercellular bile ductules along the liver cell plates 
B)  Small intrahepatic bile ductules 
C)  Small intrahepatic bile ducts 
D)  Extrahepatic bile ducts 
E)  Gallbladder 
A)  Intercellular bile ductules along the liver cell plates 
B)  Small intrahepatic bile ductules 
C)  Small intrahepatic bile ducts 
D)  Extrahepatic bile ducts 
E)  Gallbladder

Question 17

Overall,the most common cause of cirrhosis in the United States is:

Accepted Answer

A)  Viral infection 
B)  Alcohol abuse 
C)  Drug abuse 
D)  Immune hepatitis 
E)  Extrahepatic obstruction 
A)  Viral infection 
B)  Alcohol abuse 
C)  Drug abuse 
D)  Immune hepatitis 
E)  Extrahepatic obstruction

Question 18

In the preantibiotic era the most common cause of pylephlebitic abscesses of the liver was:

Accepted Answer

A)  Peptic ulcer 
B)  Crohn's disease 
C)  Ulcerative colitis 
D)  Acute appendicitis 
E)  Intestinal tuberculosis 
A)  Peptic ulcer 
B)  Crohn's disease 
C)  Ulcerative colitis 
D)  Acute appendicitis 
E)  Intestinal tuberculosis

Question 19

The nutrients reach the liver from the intestine through the:

Accepted Answer

A)  Splenic vein 
B)  Vena cava inferior 
C)  Vena cava superior 
D)  Portal vein 
E)  Hepatic vein 
A)  Splenic vein 
B)  Vena cava inferior 
C)  Vena cava superior 
D)  Portal vein 
E)  Hepatic vein

Question 20

The lack of bile adversely affects the absorption of all the following vitamins except:

Accepted Answer

A)  Vitamin A 
B)  Vitamin B₁2 
C)  Vitamin K 
D)  Vitamin D 
E)  Vitamin B 
A)  Vitamin A 
B)  Vitamin B₁2 
C)  Vitamin K 
D)  Vitamin D 
E)  Vitamin B

Exam 11: The Liver and Biliary System

Which of the following is a good serologic marker of hepatocellular carcinoma?

In hemochromatosis the liver contains increased amounts of:

In chronic liver failure there is a marked decrease of blood:

Unconjugated hyperbilirubinemia is indicative of:

Which of the following hepatitis viruses is a DNA virus with a protein envelope that contains several distinct antigens,such as surface antigen?

All the following are major functions of the liver except:

The most common malignant tumor of the liver is:

Unconjugated bilirubin circulates in the blood bound to:

Gallbladder carcinoma is:

Which of the following hepatitis viruses is currently the most common cause of cirrhosis in the United States?

Which of the following serum enzymes is the most reliable marker of extrahepatic biliary obstruction?

Complications of cirrhosis include all the following except:

In Wilson's disease the serum contains decreased amounts of:

Which immunologic finding is most typical of primary biliary cirrhosis?

Which of the following is the most common cause of cirrhosis in childhood?

Primary sclerosing cholangitis affects primarily:

Overall,the most common cause of cirrhosis in the United States is:

In the preantibiotic era the most common cause of pylephlebitic abscesses of the liver was:

The nutrients reach the liver from the intestine through the:

The lack of bile adversely affects the absorption of all the following vitamins except:

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