Question 1

_____ are drugs that are administered in an inactive form and must be metabolized to their active form.

Accepted Answer

A) Metabolites 
B) Prodrugs 
C) Lipophilics 
D) Hydrophobics 
A) Metabolites 
B) Prodrugs 
C) Lipophilics 
D) Hydrophobics B

Question 2

Absorption is greatest when the body has a good oxygen supply.

Accepted Answer

A) True 
 B)False  False

Question 3

Absorption of orally administered drugs is greatest in the _____.

Accepted Answer

A) small intestine 
B) large intestine 
C) liver 
D) pancreas 
A) small intestine 
B) large intestine 
C) liver 
D) pancreas A

Question 4

A pH of _____ is neutral.

Accepted Answer

A) 10 
B) 7 
C) 3 
D) 5 
A) 10 
B) 7 
C) 3 
D) 5

Question 5

It is difficult for lipid-soluble drugs to move across a membrane.

Accepted Answer

A) True 
 B)False

Question 6

The ability of a drug to diffuse across the cell membrane is dependent upon _____ of the drug and the _____ of the body fluid it is dissolved in.

Accepted Answer

A) properties,actions 
B) pH,actions 
C) properties,pH 
D) strength,health 
A) properties,actions 
B) pH,actions 
C) properties,pH 
D) strength,health

Question 7

_____ transport takes energy and requires special carrier proteins or pumps to "carry the drug" across the cell membrane.

Accepted Answer

A) Passive 
B) Active 
C) Drug 
D) Diffusive 
A) Passive 
B) Active 
C) Drug 
D) Diffusive

Question 8

Albumin has the greatest affinity for _____ acids and _____ drugs.

Accepted Answer

A) weak,lipophilic 
B) strong,hydrophilic 
C) weak,hydrophobic 
D) strong,lipophobic 
A) weak,lipophilic 
B) strong,hydrophilic 
C) weak,hydrophobic 
D) strong,lipophobic

Question 9

How quickly or slowly a drug is absorbed is determined by the _____.

Accepted Answer

A) characteristics of the drug 
B) drug dosage form 
C) route of administration 
D) all of the above 
A) characteristics of the drug 
B) drug dosage form 
C) route of administration 
D) all of the above

Question 10

Drugs listed in category _____ should be avoided because fetal abnormalities have been reported.

Accepted Answer

A) X 
B) B 
C) C 
D) A 
A) X 
B) B 
C) C 
D) A

Question 11

Most drugs are transported by passive transport.

Accepted Answer

A) True 
 B)False

Question 12

Distribution of the drug across the cell membrane of the blood vessel and transport to its site of action are influenced by the _____ nature of the drug.

Accepted Answer

A) physical 
B) mechanical 
C) chemical 
D) ionic 
A) physical 
B) mechanical 
C) chemical 
D) ionic

Question 13

Anatomical structures that selectively limit drug access are the _____.

Accepted Answer

A) blood-brain barrier 
B) blood-placenta barrier 
C) blood-testicular barrier 
D) all of the above 
A) blood-brain barrier 
B) blood-placenta barrier 
C) blood-testicular barrier 
D) all of the above

Question 14

The pharmacokinetic phases control the _____ of the drug's effect and the _____ of the drug action.

Accepted Answer

A) intensity,duration 
B) duration,effect 
C) mechanism,safety 
D) length,efficacy 
A) intensity,duration 
B) duration,effect 
C) mechanism,safety 
D) length,efficacy

Question 15

The body has to metabolize a drug before it is eliminated.

Accepted Answer

A) True 
 B)False

Question 16

Duration of action is the time between the _____ of action and _____ of drug action.

Accepted Answer

A) mechanism,duration 
B) onset,discontinuation 
C) duration,concentration 
D) onset,mechanism 
A) mechanism,duration 
B) onset,discontinuation 
C) duration,concentration 
D) onset,mechanism

Question 17

The time it takes for a drug to reach the concentration necessary to produce a therapeutic effect is called the _____.

Accepted Answer

A) duration of action 
B) mechanism of action 
C) onset of action 
D) length of action 
A) duration of action 
B) mechanism of action 
C) onset of action 
D) length of action

Question 18

Drugs that are administered subcutaneously are completely absorbed into the bloodstream given they are injected directly into the vein.

Accepted Answer

A) True 
 B)False

Question 19

_____ and _____ require lower doses of drug to produce therapeutic effects.

Accepted Answer

A) Infants,the elderly 
B) Teenagers,the elderly 
C) Children,adults 
D) Infants,children 
A) Infants,the elderly 
B) Teenagers,the elderly 
C) Children,adults 
D) Infants,children

Exam 2: Principles of Pharmacology

_____ are drugs that are administered in an inactive form and must be metabolized to their active form.

Absorption is greatest when the body has a good oxygen supply.

Absorption of orally administered drugs is greatest in the _____.

A pH of _____ is neutral.

It is difficult for lipid-soluble drugs to move across a membrane.

The ability of a drug to diffuse across the cell membrane is dependent upon _____ of the drug and the _____ of the body fluid it is dissolved in.

_____ transport takes energy and requires special carrier proteins or pumps to "carry the drug" across the cell membrane.

Albumin has the greatest affinity for _____ acids and _____ drugs.

How quickly or slowly a drug is absorbed is determined by the _____.

Drugs listed in category _____ should be avoided because fetal abnormalities have been reported.

Most drugs are transported by passive transport.

Distribution of the drug across the cell membrane of the blood vessel and transport to its site of action are influenced by the _____ nature of the drug.

Anatomical structures that selectively limit drug access are the _____.

The pharmacokinetic phases control the _____ of the drug's effect and the _____ of the drug action.

The body has to metabolize a drug before it is eliminated.

Duration of action is the time between the _____ of action and _____ of drug action.

The time it takes for a drug to reach the concentration necessary to produce a therapeutic effect is called the _____.

Drugs that are administered subcutaneously are completely absorbed into the bloodstream given they are injected directly into the vein.

_____ and _____ require lower doses of drug to produce therapeutic effects.

Fundamentals of Pharmacology

Pharmacodynamics

Drug Interactions and Medication Errors

Treatment of Anxiety

Treatment of Depression

Treatment of Schizophrenia and Other Psychoses

Treatment of Parkinsons Disease and Huntingtons Disease

Treatment of Seizure Disorders

Treatment of Pain

Treatment of Migraine Headache and Alzheimers Disease

Treatment of Sleep Disorders and Attention Deficit Hyperactivity Disorder

Neuromuscular Blockade

Treatment of Muscle Spasms

Treatment of Autoimmune Diseases That Affect the Musculoskeletal System

Treatment of Osteoporosis and Pagets Disease of the Bone

Treatment of Hyperuricemia and Gout

Treatment of Glaucoma

Treatment of Vertigo and Other Disorders of the Ear

Treatment of Ophthalmic and Otic Infections

Treatment of Angina

Treatment of Hypertension

Treatment of Heart Failure

Treatment of Myocardial Infarction and Stroke

Treatment of Arrhythmia

Treatment of Gastroesophageal Reflux Disease,laryngopharyngeal Reflux and Peptic Ulcer Disease

Treatment of Irritable Bowel Syndrome,ulcerative Colitis and Crohns Disease

Treatment of Asthma and Chronic Obstructive Pulmonary Disease

Treatment of Allergies

Treatment of Prostate Disease and Erectile Dysfunction

Treatment of Fluid and Electrolyte Disorders

Treatment of Thyroid Disorders

Treatment of Diabetes Mellitus

Drugs That Affect the Reproductive System

Treatment of Bacterial Infection

Treatment of Viral Infections

Treatment of Cancers

Vaccines,immunomodulators,and Immunosuppressants

Treatment of Fungal Infections

Treatment of Decubitus Ulcers and Burns

Treatment of Acne

Treatment of Eczema and Psoriasis

Treatment of Lice and Scabies

Filters

The ability of a drug to diffuse across the cell membrane is dependent upon _ of the drug and the _ of the body fluid it is dissolved in.

Albumin has the greatest affinity for _ acids and _ drugs.

The pharmacokinetic phases control the _ of the drug's effect and the _ of the drug action.

Duration of action is the time between the _ of action and _ of drug action.

_ and _ require lower doses of drug to produce therapeutic effects.