Exam 1: Immunology: Basic Principles and Applications in the Blood Bank

In a serologic test,the term prozone is also known as:

Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once. -Associated with immediate-spin in vitro reactions

Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once. -Has the highest serum concentration

After adding antigen and antibody to a test tube,one large agglutinate was observed.How should this reaction be graded?

Select the region of the antibody molecule responsible for imparting unique antibody specificity.

HLA matching between the donor and recipient is important for progenitor cell transplantation to avoid:

Select the term from the list below that best fits the definitions. -One of the two types of light chains

An antigen that originates from the individual is termed:

Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once. -Found in secretions,such as breast milk

A poor response to platelet transfusion that can be caused by antibodies to human leukocyte antigens is known as:

Hemolysis was observed at room temperature when testing a patient's serum with reagent red cells used for screening.When this test was repeated using the patient's plasma,no hemolysis was observed.What was the most likely explanation for the different reactions?

Opsonization is a term to describe what process?

Select the term from the list below that best fits the definitions. -The type of immunoglobulins determined by the heavy chain

Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once. -Able to cross the placenta

What is the potential effect in a tube agglutination test if a red cell suspension with a concentration greater than 5% is used?

Select the immunoglobulin class from the list below that best fits the characteristic described.Each class can be used more than once. -Has the highest number of antigen binding sites

In a lymphocytotoxicity test,cells that take on the dye:

Select the cell involved in humoral immunity.

What immunoglobulin class reacts best at room temperature at immediate spin?

The mixed lymphocyte culture (MLC)is a procedure that has been used in HLA testing to determine: