Exam 15: More on Causal Inference: Bias, Confounding, and Interaction

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This table shows incidence rates (per 100,000) of groups exposed to neither risk factors or to one or two risk factors for lung cancer.What is the expected value of incidence rate X on asbestos exposure group among smokers in additive scale? Incidence Rates of Lung Cancer by Asbestos and Smoking Exposure Status Smoking status Asbestos exposure Yes No Yes (regular exercise) 2.0 2.6 No (no exercise) 4.0 x

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C

Epidemiologists tried to investigate the role of factor Y in the exposure-disease relationship.They developed three tables to show the exposure-disease relationship based on the status of factor Y.Based on the information given,what is the role of factor Y in the exposure-disease relationship? Overall Case Control Exposed 1,000 500 Unexposed 200 500 Factor Y present Case Control Exposed 800 250 Unexposed 100 250 Factor Y absent Case Control Exposed 200 250 Unexposed 100 250

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Investigators think that income might be a confounder in the relationship between Hispanic ethnicity and cardiovascular disease.They conduct a case-control study,and they match cases and controls based on income.They find that Hispanics are more likely to have cardiovascular disease as compared with non-Hispanics.What is the measure of association used in such study?

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E

Epidemiologists tried to investigate the role of factor Y in the exposure-disease relationship.They developed three tables to show the exposure-disease relationship based on the status of factor Y.In this analysis,what is the odds ratio in the overall population?  Overall \text { Overall } Case Control Exposed 1,000 500 Unexposed 200 500  Factor Y present \text { Factor } Y \text { present } Case Control Exposed 800 250 Unexposed 100 250  Factor Y absent \text { Factor } Y \text { absent } Case Control Exposed 200 250 Unexposed 100 250

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Smoking participants of a cohort study are more likely to drop out.It is known that the effect of asbestos on getting cancer is much stronger among smokers.When analyzing data for this study,researchers find no association between asbestos and cancer.A potential explanation for the results of the study is

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In a case-control study,a researcher found no association between exposure to A and disease B.Later she found out that there was a misclassification when measuring exposure to A,in both cases and controls.What is a potential explanation for the results (no association) of this case-control study?

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Investigators think that income might be a confounder in the relationship between Hispanic ethnicity and cardiovascular disease.They conduct a case-control study and they match cases and controls based on income.They find that Hispanics are more likely to have cardiovascular disease as compared with non-Hispanics.What would you conclude about income as a potential confounder in this association?

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Epidemiologists tried to investigate the role of factor Z in the exposure-disease relationship.They developed three tables to show the exposure-disease relationship based on the status of factor Z.Based on the information given,what is the role of factor Z in the exposure-disease relationship?Overall Case Control Exposed 1,050 500 Unexposed 300 700 Factor X present Case Control Exposed 700 250 Unexposed 200 350 Factor X absent Case Control Exposed 350 250 Unexposed 100 350

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This table shows incidence rates (per 100,000) of groups exposed to neither risk factors or to one or two risk factors for lung cancer.What is the expected value of incidence rate X on asbestos exposure group among smokers in multiplicative scale? Incidence Rates of Lung Cancer by Asbestos and Smoking Exposure Status Smoking status Asbestos exposure Yes No Yes (regular exercise) 2.0 2.6 No (no exercise) 4.0 x

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Epidemiologists tried to investigate the role of factor X in the exposure-disease relationship.They developed three tables to show the exposure-disease relationship based on the status of factor X.Based on the information given,what is the role of factor X in the exposure-disease relationship?  Overall \text { Overall } Case Control Exposed 1,000 500 Unexposed 200 500  Factor Y present \text { Factor } Y \text { present } Case Control Exposed 800 250 Unexposed 100 250  Factor Y absent \text { Factor } Y \text { absent } Case Control Exposed 200 250 Unexposed 100 250

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