Exam 4: Overview of Radiobiology

Which of the following is not a pyrimidine?

Sublethal damage recovery can be measured in split-dose experiments.

In deciding upon treatment protocol,tumor radiosensitivity is more important to consider than normal tissue radiosensitivity.

Which of the following tissues is least radiosensitive?

Cellular response to high LET varies by dose rate.

Tumors have more SLD repair capacity than normal tissues.

The presence of oxygen increases the effectiveness of irradiation.

Mitosis occurs in germ cells.

To calculate the NSD (nominal standard dose),what factors must be known? I.total dose II.fraction size III.elapsed days

Which of the following cell types are likely to express radiation injury shortly after a D₀ dose of radiation is received? (Mark all that apply.)

D₀ is a good measure of SLD repair capacity.

What is the term describing certain chemicals or drugs that enhance the response of cells to radiation?

Carbohydrates contain enzymes.

Cells are more radiosensitive when exposed to high LET radiation.

How does oxygen retention affect radiosensitivity?

Protons have higher LET than gamma rays.

Which macromolecule is most radiosensitive?

A whole body radiation dose given in a period of seconds to minutes produces a clinical pattern called what?

The indirect action of radiation is mediated by the generation of DNA radicals.

Which of the following is the most important treatment related variable for the development of late-term effects of ionizing radiation?