Question 1

In a cross of a homozygous dominant parent and a homozygous recessive parent,what is the ratio of offspring that will exhibit the recessive phenotype?

Accepted Answer

A)  0. 
B)  1/4. 
C)  1/2. 
D)  3/4. 
E)  1. 
A)  0. 
B)  1/4. 
C)  1/2. 
D)  3/4. 
E)  1. A

Question 2

Which of the following disorders is caused by a defect in the production of an elastic connective tissue protein called fibrillin?

Accepted Answer

A)  cystic fibrosis 
B)  Tay-Sachs disease 
C)  Marfan syndrome 
D)  Huntington disease 
E)  sickle-cell disease 
A)  cystic fibrosis 
B)  Tay-Sachs disease 
C)  Marfan syndrome 
D)  Huntington disease 
E)  sickle-cell disease C

Question 3

How are Fragile X syndrome and Huntington disease similar?

Accepted Answer

A)  Both exhibit a late onset in life. 
B)  Both are trinucleotide-repeat expansion disorders. 
C)  Both affect the muscles and lead to eventual paralysis. 
D)  Both cause autism. 
E)  Both are found only in males. 
A)  Both exhibit a late onset in life. 
B)  Both are trinucleotide-repeat expansion disorders. 
C)  Both affect the muscles and lead to eventual paralysis. 
D)  Both cause autism. 
E)  Both are found only in males. B

Question 4

What is the genotype of a person with type O blood?

Accepted Answer

A)  IAIA 
B)  IAIB 
C)  IAi 
D)  IBi 
E)  ii 
A)  IAIA 
B)  IAIB 
C)  IAi 
D)  IBi 
E)  ii

Question 5

In a dihybrid cross,in which both parents are heterozygous for both traits,what is the probability that the offspring will exhibit both of the dominant phenotypes?

Accepted Answer

A) 1/16. 
B) 3/16. 
C) 6/16. 
D) 9/16. 
E) 1. 
A) 1/16. 
B) 3/16. 
C) 6/16. 
D) 9/16. 
E) 1.

Question 6

Which of the following represents a cross to determine if an individual is homozygous dominant or heterozygous?

Accepted Answer

A)  Aa x aa 
B)  AA x AA 
C)  aa x aa 
D)  Aa x AA 
E)  Aa x Aa 
A)  Aa x aa 
B)  AA x AA 
C)  aa x aa 
D)  Aa x AA 
E)  Aa x Aa

Question 7

Even though sickle-cell disease is inherited as an autosomal recessive disorder,the heterozygote can express some variation of the recessive phenotype.

Accepted Answer

A) True 
 B)False

Question 8

Which of the following is an example of a homozygous recessive genotype?

Accepted Answer

A)  aa 
B)  Aa 
C)  short 
D)  AA 
E)  ab 
A)  aa 
B)  Aa 
C)  short 
D)  AA 
E)  ab

Question 9

Which of the following would not be a common/conventional way to list someone's genotype?

Accepted Answer

A)  BB 
B)  Bb 
C)  AB 
D)  bb 
E)  AA 
A)  BB 
B)  Bb 
C)  AB 
D)  bb 
E)  AA

Question 10

How is familial hypercholesterolemia inherited?

Accepted Answer

A)  autosomal recessive 
B)  autosomal dominant 
C)  incompletely dominant 
D)  codominant 
E)  sex-linked dominant 
A)  autosomal recessive 
B)  autosomal dominant 
C)  incompletely dominant 
D)  codominant 
E)  sex-linked dominant

Question 11

If you want to know the probability that tossing two coins will result in a particular outcome (two heads,for example),you use the

Accepted Answer

A)  product rule. 
B)  sum rule. 
C)  punnett rule. 
D)  Bergman's rule. 
E)  genetics rule. 
A)  product rule. 
B)  sum rule. 
C)  punnett rule. 
D)  Bergman's rule. 
E)  genetics rule.

Question 12

There is a single gene that controls the ability to taste PTC paper.The ability to taste is dominant to the inability to taste.If you can taste the paper,it is very bitter.Which of the following genotypes can taste the paper?

Accepted Answer

A)  only PP 
B)  both PP and Pp 
C)  both PP and pp 
D)  only Pp 
E)  only pp 
A)  only PP 
B)  both PP and Pp 
C)  both PP and pp 
D)  only Pp 
E)  only pp

Question 13

Which of the following is not a characteristic of an autosomal dominant disorder pedigree?

Accepted Answer

A)  Affected children will usually have unaffected parents. 
B)  Heterozygotes are affected. 
C)  Two affected parents can produce an unaffected child. 
D)  Both males and females are affected with equal frequency. 
E)  Two unaffected parents will not have affected children. 
A)  Affected children will usually have unaffected parents. 
B)  Heterozygotes are affected. 
C)  Two affected parents can produce an unaffected child. 
D)  Both males and females are affected with equal frequency. 
E)  Two unaffected parents will not have affected children.

Question 14

Which of the following is not a characteristic of an X-linked recessive disorder pedigree?

Accepted Answer

A)  An affected son can have normal parents. 
B)  If a female has the trait, her father must also have it. 
C)  The characteristic often skips a generation. 
D)  More females than males are affected. 
E)  If a woman has the characteristic, all of her sons will have it. 
A)  An affected son can have normal parents. 
B)  If a female has the trait, her father must also have it. 
C)  The characteristic often skips a generation. 
D)  More females than males are affected. 
E)  If a woman has the characteristic, all of her sons will have it.

Question 15

Which of the following is not an autosomal recessive disorder?

Accepted Answer

A)  Marfan syndrome 
B)  Tay-Sachs disease 
C)  cystic fibrosis 
D)  sickle-cell disease 
E)  All are autosomal recessive disorders. 
A)  Marfan syndrome 
B)  Tay-Sachs disease 
C)  cystic fibrosis 
D)  sickle-cell disease 
E)  All are autosomal recessive disorders.

Question 16

In a pedigree,an affected male would be designated by

Accepted Answer

A)  an open circle. 
B)  a shaded circle. 
C)  an open square. 
D)  a shaded square. 
E)  a square with a line through it. 
A)  an open circle. 
B)  a shaded circle. 
C)  an open square. 
D)  a shaded square. 
E)  a square with a line through it.

Question 17

The definition of a multifactorial trait is one in which more than one set of alleles is involved,in which the environment plays no role.

Accepted Answer

A) True 
 B)False

Question 18

Which of the following traits would not be considered multifactorial?

Accepted Answer

A)  alcoholism 
B)  suicide risk 
C)  cleft lip/palate 
D)  diabetes 
E)  ABO blood type 
A)  alcoholism 
B)  suicide risk 
C)  cleft lip/palate 
D)  diabetes 
E)  ABO blood type

Question 19

Explain the problems associated with the genetic disorder Tay-Sachs.
A. This lysosome is responsible for clearing out the fatty acids that build up in the cells of the brain. The buildup begins to interfere with proper brain development and growth. This leads to malfunctions in vision, movement, hearing, and overall mental development. The impairment leads to blindness, seizures, paralysis, and death.

Accepted Answer

Affected children w

Question 20

If a person with type B blood marries a person with type A blood,what phenotypes can their children be?

Accepted Answer

A)  all type A 
B)  all type B 
C)  types A and O 
D)  types B and O 
E)  types A, B, O, and AB 
A)  all type A 
B)  all type B 
C)  types A and O 
D)  types B and O 
E)  types A, B, O, and AB

Exam 21: Patterns of Genetic Inheritance

In a cross of a homozygous dominant parent and a homozygous recessive parent,what is the ratio of offspring that will exhibit the recessive phenotype?

Which of the following disorders is caused by a defect in the production of an elastic connective tissue protein called fibrillin?

How are Fragile X syndrome and Huntington disease similar?

What is the genotype of a person with type O blood?

In a dihybrid cross,in which both parents are heterozygous for both traits,what is the probability that the offspring will exhibit both of the dominant phenotypes?

Which of the following represents a cross to determine if an individual is homozygous dominant or heterozygous?

Even though sickle-cell disease is inherited as an autosomal recessive disorder,the heterozygote can express some variation of the recessive phenotype.

Which of the following is an example of a homozygous recessive genotype?

Which of the following would not be a common/conventional way to list someone's genotype?

How is familial hypercholesterolemia inherited?

If you want to know the probability that tossing two coins will result in a particular outcome (two heads,for example),you use the

There is a single gene that controls the ability to taste PTC paper.The ability to taste is dominant to the inability to taste.If you can taste the paper,it is very bitter.Which of the following genotypes can taste the paper?

Which of the following is not a characteristic of an autosomal dominant disorder pedigree?

Which of the following is not a characteristic of an X-linked recessive disorder pedigree?

Which of the following is not an autosomal recessive disorder?

In a pedigree,an affected male would be designated by

The definition of a multifactorial trait is one in which more than one set of alleles is involved,in which the environment plays no role.

Which of the following traits would not be considered multifactorial?

If a person with type B blood marries a person with type A blood,what phenotypes can their children be?

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