Question 1

How does the enzyme DNA ligase contribute to DNA replication?

Accepted Answer

A) Unwinds the double helix and separates the double-stranded DNA 
B) Creates a "nick" in the DNA supercoils allowing them to straighten before replication 
C) Initiates DNA synthesis in multiple sites down the strand making the process more efficient 
D) Connects and links the individual pieces of newly synthesized DNA to form a single strand 
A) Unwinds the double helix and separates the double-stranded DNA 
B) Creates a "nick" in the DNA supercoils allowing them to straighten before replication 
C) Initiates DNA synthesis in multiple sites down the strand making the process more efficient 
D) Connects and links the individual pieces of newly synthesized DNA to form a single strand D

Question 2

What would be the expected result of a drug that affected a particular tissue by causing new DNA to form with covalent bonds instead of hydrogen bonds?

Accepted Answer

A) None of the cells in the affected tissue would be able to leave G0 and enter the cell cycle. 
B) Replication of DNA would result in identical DNA strands instead of complementary strands. 
C) Mitosis of cells in the tissue would result in the production of three new daughter cells instead of just two. 
D) The new cells that formed within this tissue would not be able to complete the next round of mitosis successfully. 
A) None of the cells in the affected tissue would be able to leave G0 and enter the cell cycle. 
B) Replication of DNA would result in identical DNA strands instead of complementary strands. 
C) Mitosis of cells in the tissue would result in the production of three new daughter cells instead of just two. 
D) The new cells that formed within this tissue would not be able to complete the next round of mitosis successfully. D

Question 3

What would be the sequence of DNA that is complementary to a DNA section with the base sequence of GGTCAATCCTTAG?

Accepted Answer

A) GATTCCTAACTGG 
B) TTGACCGAAGGCT 
C) AACTGGCTTCCGA 
D) CCAGTTAGGAATC 
A) GATTCCTAACTGG 
B) TTGACCGAAGGCT 
C) AACTGGCTTCCGA 
D) CCAGTTAGGAATC D

Question 4

What percentage of bases in a stretch of double-stranded DNA that contains 30% guanine (G)bases would be adenine (A)?

Accepted Answer

A) 70% 
B) 60% 
C) 30% 
D) 20% 
A) 70% 
B) 60% 
C) 30% 
D) 20%

Question 5

Which statement regarding chromosome structure or function is true?

Accepted Answer

A) The chromatids of any single chromosome are known as "sister chromatids." 
B) The genes located on the telomeres of chromosomes are identical to the genes in the centromeres. 
C) Immediately before the mitosis phase of cell division,the chromosomes of all somatic cells are haploid. 
D) A specific gene allele on one chromosome has a complementary allele on the other chromosome of a pair. 
A) The chromatids of any single chromosome are known as "sister chromatids." 
B) The genes located on the telomeres of chromosomes are identical to the genes in the centromeres. 
C) Immediately before the mitosis phase of cell division,the chromosomes of all somatic cells are haploid. 
D) A specific gene allele on one chromosome has a complementary allele on the other chromosome of a pair.

Question 6

Which of these complementary base pairs form the strongest or "tightest" association?

Accepted Answer

A) Adenine and thymine 
B) Cytosine and guanine 
C) Guanine and thymine 
D) Cytosine and Adenine 
A) Adenine and thymine 
B) Cytosine and guanine 
C) Guanine and thymine 
D) Cytosine and Adenine

Question 7

What is the most outstanding feature of a mature haploid cell?

Accepted Answer

A) It is usually homozygous. 
B) The sex chromosomes are missing. 
C) Only one chromosome of each pair is present. 
D) DNA synthesis occurs after mitosis instead of before. 
A) It is usually homozygous. 
B) The sex chromosomes are missing. 
C) Only one chromosome of each pair is present. 
D) DNA synthesis occurs after mitosis instead of before.

Question 8

At what phase of the cell cycle are chromosomes visible as separate structures?

Accepted Answer

A) G1 
B) G2 
C) S 
D) M 
A) G1 
B) G2 
C) S 
D) M

Question 9

What is the term used to define alternative forms of a gene that may result in different expression of the trait coded for by that gene?

Accepted Answer

A) Alleles 
B) Bases 
C) Centromeres 
D) Diploids 
A) Alleles 
B) Bases 
C) Centromeres 
D) Diploids

Question 10

What is the purpose of phosphorous in a DNA strand?

Accepted Answer

A) Linking the nucleotides into a strand 
B) Holding complementary strands together 
C) Ensuring that a purine is always paired with a pyrimidine 
D) Preventing the separation of double-stranded DNA into single-stranded DNA 
A) Linking the nucleotides into a strand 
B) Holding complementary strands together 
C) Ensuring that a purine is always paired with a pyrimidine 
D) Preventing the separation of double-stranded DNA into single-stranded DNA

Question 11

What is the term used to describe the organized picture of the paired chromosomes within a cell used to determine whether chromosome numbers,structures,and banding patterns are normal?

Accepted Answer

A) Pedigree 
B) Phenotype 
C) Karyotype 
D) Autosome 
A) Pedigree 
B) Phenotype 
C) Karyotype 
D) Autosome

Question 12

In which body or cell area are most genes in humans located?

Accepted Answer

A) Nucleus 
B) Mitochondrion 
C) Cytoplasm 
D) Plasma membrane 
A) Nucleus 
B) Mitochondrion 
C) Cytoplasm 
D) Plasma membrane

Question 13

How does the proteome differ from the genome?

Accepted Answer

A) The proteome changes in response to intracellular and extracellular signals. 
B) The genome changes in response to intracellular and extracellular signals. 
C) The proteome is stable in somatic cells and unstable in germ cells,whereas the genome is stable in both somatic cells and germ cells. 
D) The genome is stable in somatic cells and unstable in germ cells,whereas the proteome is stable in both somatic cells and germ cells. 
A) The proteome changes in response to intracellular and extracellular signals. 
B) The genome changes in response to intracellular and extracellular signals. 
C) The proteome is stable in somatic cells and unstable in germ cells,whereas the genome is stable in both somatic cells and germ cells. 
D) The genome is stable in somatic cells and unstable in germ cells,whereas the proteome is stable in both somatic cells and germ cells.

Question 14

What is the result of DNA replication?

Accepted Answer

A) Formation of two new daughter cells 
B) Formation of two identical sets of DNA 
C) Disappearance of the original parent cell 
D) Activation and attachment of spindle fibers 
A) Formation of two new daughter cells 
B) Formation of two identical sets of DNA 
C) Disappearance of the original parent cell 
D) Activation and attachment of spindle fibers

Question 15

Why does a person with normal chromosomes only have two alleles for any single gene trait?

Accepted Answer

A) A minimum of two alleles is required for the expression of monogenic traits. 
B) When a dominant allele is paired with a recessive allele,only the dominant allele is expressed and the recessive allele is silent. 
C) One allele for the monogenic trait is on the paternally derived chromosome and the other allele is on the maternally derived chromosome. 
D) Expression of more than two alleles of any single gene trait results in enhanced expression of recessive alleles and suppressed expression of dominant alleles. 
A) A minimum of two alleles is required for the expression of monogenic traits. 
B) When a dominant allele is paired with a recessive allele,only the dominant allele is expressed and the recessive allele is silent. 
C) One allele for the monogenic trait is on the paternally derived chromosome and the other allele is on the maternally derived chromosome. 
D) Expression of more than two alleles of any single gene trait results in enhanced expression of recessive alleles and suppressed expression of dominant alleles.

Question 16

What is the correct interpretation of the statement "the HFE gene locus is 6p21"?

Accepted Answer

A) Both alleles of the HFE gene are equally expressed. 
B) The HFE gene is inherited from the paternal chromosome line. 
C) The HFE gene alleles are located on the "short arms" of chromosome number 6. 
D) There is a somatic cell mutation involving gene allele damage on chromosome 6. 
A) Both alleles of the HFE gene are equally expressed. 
B) The HFE gene is inherited from the paternal chromosome line. 
C) The HFE gene alleles are located on the "short arms" of chromosome number 6. 
D) There is a somatic cell mutation involving gene allele damage on chromosome 6.

Question 17

Which statement about G0 is true?

Accepted Answer

A) Hyperplastic growth in place of hypertrophic growth 
B) Performance of specific differentiated functions 
C) Initiation and completion of nucleokinesis 
D) Replication of DNA 
A) Hyperplastic growth in place of hypertrophic growth 
B) Performance of specific differentiated functions 
C) Initiation and completion of nucleokinesis 
D) Replication of DNA

Question 18

What activity occurs during S phase of the cell cycle?

Accepted Answer

A) The cell undergoes cytokinesis. 
B) Activity stops and the cell "sleeps." 
C) All DNA is completely replicated. 
D) Chromosomes separate causing nucleokinesis. 
A) The cell undergoes cytokinesis. 
B) Activity stops and the cell "sleeps." 
C) All DNA is completely replicated. 
D) Chromosomes separate causing nucleokinesis.

Question 19

Which condition or statement exemplifies the concept of genomics rather than genetics?

Accepted Answer

A) The gene for insulin is located on chromosome 11 in all people. 
B) Expression of any single gene is dependent on inheriting two alleles. 
C) Sex-linked recessive disorders affect males more often than females. 
D) One allele for each gene is inherited from the mother and one is inherited from the father. 
A) The gene for insulin is located on chromosome 11 in all people. 
B) Expression of any single gene is dependent on inheriting two alleles. 
C) Sex-linked recessive disorders affect males more often than females. 
D) One allele for each gene is inherited from the mother and one is inherited from the father.

Question 20

Under what normal condition are genotype and phenotype always the same?

Accepted Answer

A) Trisomy of alleles 
B) Triploidy of alleles 
C) Homozygosity of alleles 
D) Heterozygosity of alleles 
A) Trisomy of alleles 
B) Triploidy of alleles 
C) Homozygosity of alleles 
D) Heterozygosity of alleles

How does the enzyme DNA ligase contribute to DNA replication?

What would be the expected result of a drug that affected a particular tissue by causing new DNA to form with covalent bonds instead of hydrogen bonds?

What would be the sequence of DNA that is complementary to a DNA section with the base sequence of GGTCAATCCTTAG?

What percentage of bases in a stretch of double-stranded DNA that contains 30% guanine (G)bases would be adenine (A)?

Which statement regarding chromosome structure or function is true?

Which of these complementary base pairs form the strongest or "tightest" association?

What is the most outstanding feature of a mature haploid cell?

At what phase of the cell cycle are chromosomes visible as separate structures?

What is the term used to define alternative forms of a gene that may result in different expression of the trait coded for by that gene?

What is the purpose of phosphorous in a DNA strand?

What is the term used to describe the organized picture of the paired chromosomes within a cell used to determine whether chromosome numbers,structures,and banding patterns are normal?

In which body or cell area are most genes in humans located?

How does the proteome differ from the genome?

What is the result of DNA replication?

Why does a person with normal chromosomes only have two alleles for any single gene trait?

What is the correct interpretation of the statement "the HFE gene locus is 6p21"?

Which statement about G₀ is true?

What activity occurs during S phase of the cell cycle?

Which condition or statement exemplifies the concept of genomics rather than genetics?

Under what normal condition are genotype and phenotype always the same?

Protein Synthesis

Genetic Influences on Cell Growth, cell Differentiation, and Gametogenesis

Patterns of Inheritance

Chromosomal and Mitochondrial Inheritance and Disorders

Family History and Pedigree Construction

Congenital Anomalies, basic Dysmorphology, and Genetic Assessment

Enzyme and Collagen Disorders

Common Childhood-Onset Genetic Disorders

Common Adult-Onset Genetic Disorders

Cardiovascular Disorders

The Genetics of Cancer

Genetic Contributions to Psychiatric and Behavioral Disorders

Genetic and Genomic Testing

Assessing Genomic Variation in Drug Response

Health Professionals and Genomic Care

Financial,legal,ethical,and Social Considerations

Genetic and Genomic Variation

Filters

Exam 1: DNA Structure and Function

How does the enzyme DNA ligase contribute to DNA replication?

What would be the expected result of a drug that affected a particular tissue by causing new DNA to form with covalent bonds instead of hydrogen bonds?

What would be the sequence of DNA that is complementary to a DNA section with the base sequence of GGTCAATCCTTAG?

What percentage of bases in a stretch of double-stranded DNA that contains 30% guanine (G)bases would be adenine (A)?

Which statement regarding chromosome structure or function is true?

Which of these complementary base pairs form the strongest or "tightest" association?

What is the most outstanding feature of a mature haploid cell?

At what phase of the cell cycle are chromosomes visible as separate structures?

What is the term used to define alternative forms of a gene that may result in different expression of the trait coded for by that gene?

What is the purpose of phosphorous in a DNA strand?

What is the term used to describe the organized picture of the paired chromosomes within a cell used to determine whether chromosome numbers,structures,and banding patterns are normal?

In which body or cell area are most genes in humans located?

How does the proteome differ from the genome?

What is the result of DNA replication?

Why does a person with normal chromosomes only have two alleles for any single gene trait?

What is the correct interpretation of the statement "the HFE gene locus is 6p21"?

Which statement about G0 is true?

What activity occurs during S phase of the cell cycle?

Which condition or statement exemplifies the concept of genomics rather than genetics?

Under what normal condition are genotype and phenotype always the same?

Protein Synthesis

Genetic Influences on Cell Growth, cell Differentiation, and Gametogenesis

Patterns of Inheritance

Chromosomal and Mitochondrial Inheritance and Disorders

Family History and Pedigree Construction

Congenital Anomalies, basic Dysmorphology, and Genetic Assessment

Enzyme and Collagen Disorders

Common Childhood-Onset Genetic Disorders

Common Adult-Onset Genetic Disorders

Cardiovascular Disorders

The Genetics of Cancer

Genetic Contributions to Psychiatric and Behavioral Disorders

Genetic and Genomic Testing

Assessing Genomic Variation in Drug Response

Health Professionals and Genomic Care

Financial,legal,ethical,and Social Considerations

Genetic and Genomic Variation

Filters

Which statement about G₀ is true?