Exam 5: Methods and Strategies of Research

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Transcranial magnetic stimulation is used to temporarily ________ local regions of cortex.

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inactivate

Which of the following is true of the experimental ablation technique?

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A

Explain how the activity of brain cells is measured using autoradiography.

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Brain cells require glucose as fuel for activity. 2-DG, like glucose, is taken up into neurons, but cannot be used for energy. If a radioactive version of 2-DG is injected into an animal, radioactive 2-DG molecules will accumulate in the brain as a function of the relative activity of those cells. Autoradiography will reveal the presence of radioactive molecules in the brain, with a more intense signal in regions that were more active and a less intense signal in less active regions.

Single-unit recordings

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The RNA, DNA, and associated proteins in cell bodies are collectively referred to as

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Which term below means "moving forward"?

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The textbook suggests that brain tissue can be fixed with ________ to prevent autolysis.

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How did the neurosurgeons detect the fact that clamping off Mrs. F.'s left common carotid artery produced insufficient blood flow to her brain?

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The chemical ________ can be used to trace the paths of afferent axons.

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The major advantage of chemical stimulation using glutamate infusion is that

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The photoprotein NpHR controls a ________ channel and is sensitive to yellow light.

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The key advantage of a reversible lesion is that

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Neurons can be activated by

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Which of the following chemicals can be used to create a reversible lesion in brain tissue?

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The ________ technique could be used to trace axons that are afferent to the injected region.

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The textbook suggests that ________ is a common drug that can be used in retrograde tracing procedures.

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The three numbers listed on a page of a stereotaxic atlas refer to

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To determine the location of a lesion after the sacrifice of an animal, brain slices created with a ___________ are stained to visualize the brain areas.

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________ are produced by some white blood cells and act to destroy invading microorganisms in the body.

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Explain how and why the brain is preserved during the histology process.

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