Exam 17: Drug Development, Evaluation and Safety

Which of the following tests characterises the drug screening process?

Into which medicines in pregnancy category is a drug assigned that has caused or is suspected of causing fetal harm,but not malformations?

Subacute toxicity tests are characterised by:

The ability of a drug to produce an effect at a receptor is referred to as:

What does it mean when a medicine is sold under patent?

The transfer of drugs from the maternal circulation into fetal circulation depends on the dose and physicochemical properties of the drug,and transplacental transport systems.

The final decision to approve a drug for marketing in Australia and New Zealand rests with the:

Which form of hypersensitivity reaction is characterised by antibody-antigen complexes that precipitate out of the blood and lodge in tissues such as skin and joints,inducing an inflammatory response?

The terms side effect and adverse effects are interchangeable.

A protein-bound drug may get displaced by another drug through competition for binding sites on plasma proteins.The displaced drug may then exert toxicity if it has a lower margin of safety.

A type of hypersensitivity reaction to a drug,described as anaphylaxis,which is mediated by IgE antibodies,is a:

Only a few medicines are excreted in breast milk.