Question 1

A CSF protein report of 32 g/dL:

Accepted Answer

A)  Is normal 
B)  Indicates possible multiple sclerosis 
C)  Is an erroneous report 
D)  Should be followed by electrophoresis 
A)  Is normal 
B)  Indicates possible multiple sclerosis 
C)  Is an erroneous report 
D)  Should be followed by electrophoresis C

Question 2

A patient previously diagnosed with acquired immunodeficiency arrives in the emergency room with symptoms of meningitis.A lumbar puncture is performed.
-Using the information provided,in addition to Gram stain,what additional testing should be performed?

Accepted Answer

A)  VDRL 
B)  Electrophoresis 
C)  Cryptococcal antigen test 
D)  Differential of peripheral blood 
A)  VDRL 
B)  Electrophoresis 
C)  Cryptococcal antigen test 
D)  Differential of peripheral blood C

Question 3

The IgG index is a comparison between the:

Accepted Answer

A)  CSF IgG and serum IgG 
B)  CSF albumin index and serum IgG 
C)  CSF/serum albumin index and CSF/serum IgG index 
D)  Serum albumin and CSF/serum IgG index 
A)  CSF IgG and serum IgG 
B)  CSF albumin index and serum IgG 
C)  CSF/serum albumin index and CSF/serum IgG index 
D)  Serum albumin and CSF/serum IgG index C

Question 4

CSF is produced primarily by:

Accepted Answer

A)  Secretion by cells of the arachnoid villi 
B)  Diffusion from the plasma into the central nervous system (CNS) 
C)  Selective filtration of plasma in the choroid plexus 
D)  Excretions from the ependymal cells lining the central nervous system 
A)  Secretion by cells of the arachnoid villi 
B)  Diffusion from the plasma into the central nervous system (CNS) 
C)  Selective filtration of plasma in the choroid plexus 
D)  Excretions from the ependymal cells lining the central nervous system

Question 5

Calculate the WBC count in the following from the information provided:
-Using a 1:10 dilution,120 cells are counted in the four large corner squares on one side of the hemocytometer.

Accepted Answer

A)  120 cells/µL 
B)  1200 cells/µL 
C)  2000 cells/µL 
D)  3000 cells/µL 
A)  120 cells/µL 
B)  1200 cells/µL 
C)  2000 cells/µL 
D)  3000 cells/µL

Question 6

If CSF tubes numbered 2 and 3 cannot be analyzed within 1 hour,the correct procedure is to:

Accepted Answer

A)  Refrigerate both tubes 
B)  Leave both tubes at room temperature 
C)  Refrigerate tube 2 and freeze tube 3 
D)  Refrigerate tube 3 and leave tube 2 at room temperature 
A)  Refrigerate both tubes 
B)  Leave both tubes at room temperature 
C)  Refrigerate tube 2 and freeze tube 3 
D)  Refrigerate tube 3 and leave tube 2 at room temperature

Question 7

The presence of hemosiderin containing macrophages in CSF indicates:

Accepted Answer

A)  Fungal meningitis 
B)  Cerebral hemorrhage 
C)  Reye's syndrome 
D)  Multiple sclerosis 
A)  Fungal meningitis 
B)  Cerebral hemorrhage 
C)  Reye's syndrome 
D)  Multiple sclerosis

Question 8

When a CSF specimen is received in the microbiology laboratory,the first thing the technologist should do is:

Accepted Answer

A)  Perform a Gram stain 
B)  Perform an India ink preparation 
C)  Centrifuge the specimen 
D)  Streak the fluid on chocolate agar 
A)  Perform a Gram stain 
B)  Perform an India ink preparation 
C)  Centrifuge the specimen 
D)  Streak the fluid on chocolate agar

Question 9

A questionable India ink preparation on the CSF from an immunocompromised patient should be further tested using:

Accepted Answer

A)  A cryptococcal antigen test 
B)  A bacterial antigen panel 
C)  Counterimmunoelectrophoresis 
D)  An anaerobic culture 
A)  A cryptococcal antigen test 
B)  A bacterial antigen panel 
C)  Counterimmunoelectrophoresis 
D)  An anaerobic culture

Question 10

To determine if IgG is being produced within the central nervous system,the laboratory must calculate the:

Accepted Answer

A)  IgG index 
B)  Serum albumin index 
C)  IgG/albumin index 
D)  CSF/albumin index 
A)  IgG index 
B)  Serum albumin index 
C)  IgG/albumin index 
D)  CSF/albumin index

Question 11

Calculate the WBC count in the following from the information provided:
-Using an undiluted specimen,100 cells are counted in the nine large squares on one side of the hemocytometer.

Accepted Answer

A)  90 cells/µL 
B)  111 cells/µL 
C)  901 cells/µL 
D)  1111 cells/µL 
A)  90 cells/µL 
B)  111 cells/µL 
C)  901 cells/µL 
D)  1111 cells/µL

Question 12

Xanthochromic CSF may appear pink,orange,or yellow.

Accepted Answer

A) True 
 B)False

Question 13

A broad spectrum of reactive and nonreactive lymphocytes in the CSF is associated with:

Accepted Answer

A)  Bacterial meningitis 
B)  Allergic reactions 
C)  Cerebral hemorrhage 
D)  Viral meningitis 
A)  Bacterial meningitis 
B)  Allergic reactions 
C)  Cerebral hemorrhage 
D)  Viral meningitis

Question 14

Normal CSF protein differs from serum protein by the:

Accepted Answer

A)  Presence of IgG 
B)  Presence of haptoglobin 
C)  Presence of ceruloplasmin 
D)  Absence of fibrinogen 
A)  Presence of IgG 
B)  Presence of haptoglobin 
C)  Presence of ceruloplasmin 
D)  Absence of fibrinogen

Question 15

CSF electrophoresis can be used to confirm the diagnosis of multiple sclerosis and would be expected to show which of the following?

Accepted Answer

A)  Increased IgG with oligoclonal bands not seen on serum electrophoresis 
B)  Increased IgG with oligoclonal bands similar to those seen on serum electrophoresis 
C)  Decreased IgG with antibody-specific oligoclonal bands 
D)  Decreased IgG with oligoclonal bands resembling those seen on serum electrophoresis 
A)  Increased IgG with oligoclonal bands not seen on serum electrophoresis 
B)  Increased IgG with oligoclonal bands similar to those seen on serum electrophoresis 
C)  Decreased IgG with antibody-specific oligoclonal bands 
D)  Decreased IgG with oligoclonal bands resembling those seen on serum electrophoresis

Question 16

Examination of a CSF shows 1000 WBCs,of which 75% are lymphocytes and 25% are monocytes.This finding is consistent with:

Accepted Answer

A)  Normal spinal fluid 
B)  Bacterial meningitis 
C)  Viral meningitis 
D)  Multiple sclerosis 
A)  Normal spinal fluid 
B)  Bacterial meningitis 
C)  Viral meningitis 
D)  Multiple sclerosis

Question 17

A false-positive CSF serologic test for neurosyphilis in a treated patient can occur if:

Accepted Answer

A)  The VDRL testing method is used 
B)  Fluid from a traumatic tap is tested by the FTA-ABS test 
C)  The fluid is frozen before testing 
D)  Increased protein is present in the fluid 
A)  The VDRL testing method is used 
B)  Fluid from a traumatic tap is tested by the FTA-ABS test 
C)  The fluid is frozen before testing 
D)  Increased protein is present in the fluid

Question 18

A lumbar puncture is performed on a 40-year-old man experiencing symptoms of blurred vision and numbness in his extremities.Results are:  
-Using the information provided,based on the symptoms and laboratory tests ordered,what disorder does the physician suspect?

Accepted Answer

A)  Late cerebral hemorrhage 
B)  Viral meningitis 
C)  Multiple sclerosis 
D)  CSF leakage 
A)  Late cerebral hemorrhage 
B)  Viral meningitis 
C)  Multiple sclerosis 
D)  CSF leakage

Question 19

Neutrophils may be present in normal CSF.

Accepted Answer

A) True 
 B)False

Question 20

When calculating an IgG index,the serum albumin concentration must be converted to milligrams per deciliter.

Accepted Answer

A) True 
 B)False

A CSF protein report of 32 g/dL:

A patient previously diagnosed with acquired immunodeficiency arrives in the emergency room with symptoms of meningitis.A lumbar puncture is performed. -Using the information provided,in addition to Gram stain,what additional testing should be performed?

The IgG index is a comparison between the:

CSF is produced primarily by:

Calculate the WBC count in the following from the information provided: -Using a 1:10 dilution,120 cells are counted in the four large corner squares on one side of the hemocytometer.

If CSF tubes numbered 2 and 3 cannot be analyzed within 1 hour,the correct procedure is to:

The presence of hemosiderin containing macrophages in CSF indicates:

When a CSF specimen is received in the microbiology laboratory,the first thing the technologist should do is:

A questionable India ink preparation on the CSF from an immunocompromised patient should be further tested using:

To determine if IgG is being produced within the central nervous system,the laboratory must calculate the:

Calculate the WBC count in the following from the information provided: -Using an undiluted specimen,100 cells are counted in the nine large squares on one side of the hemocytometer.

Xanthochromic CSF may appear pink,orange,or yellow.

A broad spectrum of reactive and nonreactive lymphocytes in the CSF is associated with:

Normal CSF protein differs from serum protein by the:

CSF electrophoresis can be used to confirm the diagnosis of multiple sclerosis and would be expected to show which of the following?

Examination of a CSF shows 1000 WBCs,of which 75% are lymphocytes and 25% are monocytes.This finding is consistent with:

A false-positive CSF serologic test for neurosyphilis in a treated patient can occur if:

A lumbar puncture is performed on a 40-year-old man experiencing symptoms of blurred vision and numbness in his extremities.Results are: -Using the information provided,based on the symptoms and laboratory tests ordered,what disorder does the physician suspect?

Neutrophils may be present in normal CSF.

When calculating an IgG index,the serum albumin concentration must be converted to milligrams per deciliter.

Safety and Quality Assessment

Introduction to Urinalysis

Renal Function

Physical Examination of Urine

Chemical Examination of Urine

Microscopic Examination of Urine

Renal Disease

Urine Screening for Metabolic Disorders

Semen

Synovial Fluid

Serous Fluid

Amniotic Fluid

Fecal Analysis

Vaginal Secretions

Filters

Exam 9: Cerebrospinal Fluid

A CSF protein report of 32 g/dL:

A patient previously diagnosed with acquired immunodeficiency arrives in the emergency room with symptoms of meningitis.A lumbar puncture is performed. -Using the information provided,in addition to Gram stain,what additional testing should be performed?

The IgG index is a comparison between the:

CSF is produced primarily by:

Calculate the WBC count in the following from the information provided: -Using a 1:10 dilution,120 cells are counted in the four large corner squares on one side of the hemocytometer.

If CSF tubes numbered 2 and 3 cannot be analyzed within 1 hour,the correct procedure is to:

The presence of hemosiderin containing macrophages in CSF indicates:

When a CSF specimen is received in the microbiology laboratory,the first thing the technologist should do is:

A questionable India ink preparation on the CSF from an immunocompromised patient should be further tested using:

To determine if IgG is being produced within the central nervous system,the laboratory must calculate the:

Calculate the WBC count in the following from the information provided: -Using an undiluted specimen,100 cells are counted in the nine large squares on one side of the hemocytometer.

Xanthochromic CSF may appear pink,orange,or yellow.

A broad spectrum of reactive and nonreactive lymphocytes in the CSF is associated with:

Normal CSF protein differs from serum protein by the:

CSF electrophoresis can be used to confirm the diagnosis of multiple sclerosis and would be expected to show which of the following?

Examination of a CSF shows 1000 WBCs,of which 75% are lymphocytes and 25% are monocytes.This finding is consistent with:

A false-positive CSF serologic test for neurosyphilis in a treated patient can occur if:

A lumbar puncture is performed on a 40-year-old man experiencing symptoms of blurred vision and numbness in his extremities.Results are: -Using the information provided,based on the symptoms and laboratory tests ordered,what disorder does the physician suspect?

Neutrophils may be present in normal CSF.

When calculating an IgG index,the serum albumin concentration must be converted to milligrams per deciliter.

Safety and Quality Assessment

Introduction to Urinalysis

Renal Function

Physical Examination of Urine

Chemical Examination of Urine

Microscopic Examination of Urine

Renal Disease

Urine Screening for Metabolic Disorders

Semen

Synovial Fluid

Serous Fluid

Amniotic Fluid

Fecal Analysis

Vaginal Secretions

Filters