Deck 41: Microcirculation and Solute Exchange

Question 1

The m ajor force opposing fluid filtration from the capillaries to the interstitial fluid is the

A) Capillary hydrostatic pressure
B) Cap illary onc otic p ressu re
C) Interstitial fluid hydrostatic pressure
D) Interstitial fluid oncotic pressure
E) Filtration coefficient

Answer 1

B

Question 2

Flow-limited transfer refers to transfer that

A) Occ urs by bulk flow across the c apillary
B) Increases nearly linearly with flow
C) Is lim ited by the con cen tration o f solu te
D) Occurs when the diffusion gradient is greatest
E) Occurs when flow is fastest

Answer 2

B

Question 3

G ro win g c hild re n s ub jec ted to lo w p ro tein die ts h av e lo we r lev els of a lbu m in in the ir blo od . T his should cause

A). Se ptic em ia
B) An em ia
C) Lactose intolerance
D) Edema
E) Fila ria sis

Answer 3

D

Question 4

Diffusion-limited transfer refers to transfer that

A) Occurs when the diffusion gradient is greatest and flow is greatest
B) Occurs then the diffusion gradient is greatest because flow is slow
C) Increases nearly linearly with flow
D) Occ urs by bulk flow across the c apillary
E) Occurs due to saturable transport mechanisms

Question 5

The lymphatics

A) Ar e m os t pr om ine nt in the bra in
B) M os tly co nta in c irc ula ting pla sm a c ells
C) Contain most of the vitamins from food
D) Drain excess interstitial fluid from the tissues
E) Keep the venous pressures above arterial values

Question 6

Continuous capillaries are most likely to be found in the

A) Mu scles
B) Liver
C) Intestines
D) Bone marrow
E) Spleen

Question 7

The m ajo r fo rc e fa vo rin g flu id filt ra tion fro m the ca pilla rie s in to th e in ter stitia l fluid is the

A) Cap illary hydro static p ressu re
B) Capillary oncotic pressure
C) Interstitial fluid hydrostatic pressure
D) Interstitial fluid oncotic pressure
E) Filtration coefficient

Question 8

Which of the following does NOT Increase nutrient delivery to the tissues

A) Incre asin g the surf ace area , S
B) Incre asin g the perm eab ility, p
C) De cre asin g the diffus ion dis tanc e, ð
D) De crea sing the flow , Q V
E) De cre asin g the inters titial fluid con cen tration, C i

Question 9

Unidirectional flow through the lymph circulation is assured by the

A) Muscle pumps
B) Pressure gradients
C) Va lve s in th e lym ph ve sse ls
D) Gr avity
E) Movem ent of lymphocytes

Question 10

Daily lymph flow should be Increased by

A) Increased central venous pres sure
B) Decre ased arterial pressure
C) Increased ECF volume
D) Increased plasma protein concentration
E) Both A and C are correct

Question 11

Discontinuous capillaries are most likely to be found in the

A) Br ain
B) Sk in
C) Sk ele tal m us cle
D) Cornea
E) Bone marrow

Question 12

The colloid osmotic pressure or oncotic pressure is the

A) Hydrostatic pressure in the colloid, of interstitial space
B) The osm otic pressure due to low-molecular weight solutes
C) The osmotic pressure due to the proteins in solution
D) The pressure due to the inertia of the fluid in the interstitial space
E) T he dra g o f pr ote in o n th e m ov em en t of fluid

Question 13

Fenestrated capillaries are most likely to be found in the

A) Liver
B) Muscles
C) Sk in
D) Br ain
E) Kidney

Question 14

Blockage of the lymph vessels causes

A) Massive inflamm ation
B) Dehydration of the body due to lack of lym ph return
C) Edema peripheral to the blockade
D) Edema proximal to the blockade
E) Cong estive heart failure

Question 15

The cycling of open states among the arterioles that perfuse a tissue is called

A) Vasoconstriction
B) Vasodilation
C) V asectomy
D) Vaso-vaso syncope
E) Vasomotion

Question 16

Which of the following does NO T participate in the determination of the conce ntration of a metabolite in the interstitial fluid?

A) T he pe rm ea bility o f th e s olu te th ro ug h th e c ap illary w all
B) The flow of fluid through the capillaries perfusing the tissue
C) The rate of pro duc tion or c ons um ption o f the m etab olite
D) T he su rfa ce are a o f th e c ap illary w all
E) None of the above

Question 17

Which of the following mechanisms are NOT used to transfer nutrients across capillaries?

A) Pass ive transport
B) Solvent drag by bulk flow
C) Active tra nsp ort
D) T ra ns cyto sis
E) Diffusion

Question 18

At very high flow rates, the concentration of a diffusable metabolite in the ISF

A) Goe s to zero
B) Approa ches th e arteriolar conce ntration o f the m etabo lite
C) Ap proa che s the cytoso lic con cen tration o f the m etab olite
D) Approaches a fraction (1-E) of the arteriolar concentration
E) Ap proa che s the rate o f m etab olism of the m etab olite, Q M, div ide d b y E