Deck 11: Active Transport: Pumps and Exchangers

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Question
An ex am ple of a prim ar y ac tive tra ns po rt m ec ha nis m is

A) SGLT-1
B) NHE
C) NCX
D) SERCA
E) NIS
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Question
Secondary active transport mechanisms

A) Hydrolyze ATP
B) Co up le m ov em en t of o ne m ater ial dow n its electrochemical gradient with another solute moving up its electrochemical gradient
C) Cannot concentrate solutes
D) Are facilitated diffusion mechanisms
E) Ar e n ot s atu ra ble
Question
The sto ich iom etr y of t he Na ,K- AT Pa se is

A) 3 Na+ ions are pumped into the cell with 2 K+ ions being pumped out
B) 3 Na+ ions move in and 1 Ca2+ ion moves out
C) 1 Na+ ion m ov es ou t with ev er y K+ ion tha t m ov es in
D) 3 Na+ ions are pum ped out of the cell with 2 K+ ion s be ing pu m pe d in
E) 3 Na+ ions are pumped out of the cell with each K+ ion be ing pu m pe d in
Question
For most cells in the body, the intracellular free [Ca2+] is about

A) 12 mM
B) 1.2 mM
C) 0.12 mM
D) 10.2 µM
E) Less than 1µ M
Question
A symport is a transport mechanism that

A) T ra ns po rts ion s a cr os s th e s ym ph ysis
B) Transports two solutes in the same direction
C) Transports one solute down its electrochemical gradient
D) Transports two solutes in opposite directions
E) Transports one solute up its electrochemical gradient
Question
The electrochemical potential for an ion in solution is given as

A) µ = RT ln C + z ; ¡
B) µ = µ0 + RT C + z ; ¡ 6 C + z ; 6¡
D) µ = µ 0 + RT ln C + z ; ¡
E) µ = -RT ln K eq
Question
Which of the following is a secondary active transport mechanism?

A) Na,K-ATPase
B) PMCA
C) NCX
D) SPCA
E) SERCA
Question
Which of the following does NOT work through a primary active transport mechanism?

A) SERCA
B) Na,K-ATPase
C) PMCA
D) SG LT -1
E) H-K-ATPase
Question
The sto ich iom etr y of t he NC X is

A) 3 Na+ ions for every Ca2+ ion
B) 2 Na+ ions for every Ca2+ ion
C) 1 Na+ ion for every Ca2+ ion
D) 3 Na+ ions for every 2 Ca2+ ions
E) 2 Na+ ions for every 2 Ca2+ ions
Question
Primary active transport mechanisms

A) Use the energy of the Na+ grad ient to p owe r "up hill" trans port o f ano ther s olute
B) Hydrolyze ATP
C) Are facilitated diffusion mechanisms
D) Cannot concentrate solutes
E) Transport only ions
Question
Which of the following is NOT a secondary active transport mechanism?

A) H,K-ATPase
B) SG LT-1
C) NCX
D) NIS
E) NHE
Question
For most cells in the body, the extracellular [Na+] is abo ut

A) 290 mM
B) 145 mM
C) 60 mM
D) 12 mM
E) 4 mM
Question
An ex am ple of a sym po rt is

A) SGLT1
B) NCX
C) NHE
D) AE
E) Na,K-ATPase
Question
Active Transport mechanisms

A) Equilibrate the concentration of a solute across a mem brane
B) Move at least one substrate from a region of lower electrochemical potential to a region of higher electrochemical potential
C) Do not respond to differences in potential across a mem brane
D) Move only ions
E) Do not require metabolic energy
Question
For most cells in the body, the intracellular [Na+] is about

A) 290 mM
B) 145 mM
C) 60 mM
D) 12 mM
E) 4 mM
Question
Active transport differs from passive transport in that

A) Ac tive tra ns po rt is sa tur ab le w he re as pa ss ive tra ns po rt is no t sa tur ab le
B) Active transport requires metabolic energy whereas passive transport does not
C) Active transport displays competition whereas passive transport does not
D) Active transport moves things from high to low electrochemical potential whereas passive transport moves them the other way
E) Active transport involves proteins, whereas passive transport does not
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Deck 11: Active Transport: Pumps and Exchangers
1
An ex am ple of a prim ar y ac tive tra ns po rt m ec ha nis m is

A) SGLT-1
B) NHE
C) NCX
D) SERCA
E) NIS
D
2
Secondary active transport mechanisms

A) Hydrolyze ATP
B) Co up le m ov em en t of o ne m ater ial dow n its electrochemical gradient with another solute moving up its electrochemical gradient
C) Cannot concentrate solutes
D) Are facilitated diffusion mechanisms
E) Ar e n ot s atu ra ble
B
3
The sto ich iom etr y of t he Na ,K- AT Pa se is

A) 3 Na+ ions are pumped into the cell with 2 K+ ions being pumped out
B) 3 Na+ ions move in and 1 Ca2+ ion moves out
C) 1 Na+ ion m ov es ou t with ev er y K+ ion tha t m ov es in
D) 3 Na+ ions are pum ped out of the cell with 2 K+ ion s be ing pu m pe d in
E) 3 Na+ ions are pumped out of the cell with each K+ ion be ing pu m pe d in
D
4
For most cells in the body, the intracellular free [Ca2+] is about

A) 12 mM
B) 1.2 mM
C) 0.12 mM
D) 10.2 µM
E) Less than 1µ M
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5
A symport is a transport mechanism that

A) T ra ns po rts ion s a cr os s th e s ym ph ysis
B) Transports two solutes in the same direction
C) Transports one solute down its electrochemical gradient
D) Transports two solutes in opposite directions
E) Transports one solute up its electrochemical gradient
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6
The electrochemical potential for an ion in solution is given as

A) µ = RT ln C + z ; ¡
B) µ = µ0 + RT C + z ; ¡ 6 C + z ; 6¡
D) µ = µ 0 + RT ln C + z ; ¡
E) µ = -RT ln K eq
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7
Which of the following is a secondary active transport mechanism?

A) Na,K-ATPase
B) PMCA
C) NCX
D) SPCA
E) SERCA
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8
Which of the following does NOT work through a primary active transport mechanism?

A) SERCA
B) Na,K-ATPase
C) PMCA
D) SG LT -1
E) H-K-ATPase
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9
The sto ich iom etr y of t he NC X is

A) 3 Na+ ions for every Ca2+ ion
B) 2 Na+ ions for every Ca2+ ion
C) 1 Na+ ion for every Ca2+ ion
D) 3 Na+ ions for every 2 Ca2+ ions
E) 2 Na+ ions for every 2 Ca2+ ions
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10
Primary active transport mechanisms

A) Use the energy of the Na+ grad ient to p owe r "up hill" trans port o f ano ther s olute
B) Hydrolyze ATP
C) Are facilitated diffusion mechanisms
D) Cannot concentrate solutes
E) Transport only ions
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11
Which of the following is NOT a secondary active transport mechanism?

A) H,K-ATPase
B) SG LT-1
C) NCX
D) NIS
E) NHE
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12
For most cells in the body, the extracellular [Na+] is abo ut

A) 290 mM
B) 145 mM
C) 60 mM
D) 12 mM
E) 4 mM
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13
An ex am ple of a sym po rt is

A) SGLT1
B) NCX
C) NHE
D) AE
E) Na,K-ATPase
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14
Active Transport mechanisms

A) Equilibrate the concentration of a solute across a mem brane
B) Move at least one substrate from a region of lower electrochemical potential to a region of higher electrochemical potential
C) Do not respond to differences in potential across a mem brane
D) Move only ions
E) Do not require metabolic energy
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k this deck
15
For most cells in the body, the intracellular [Na+] is about

A) 290 mM
B) 145 mM
C) 60 mM
D) 12 mM
E) 4 mM
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k this deck
16
Active transport differs from passive transport in that

A) Ac tive tra ns po rt is sa tur ab le w he re as pa ss ive tra ns po rt is no t sa tur ab le
B) Active transport requires metabolic energy whereas passive transport does not
C) Active transport displays competition whereas passive transport does not
D) Active transport moves things from high to low electrochemical potential whereas passive transport moves them the other way
E) Active transport involves proteins, whereas passive transport does not
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