Question 1

The stoichiometry of the Na ,K- AT Pase is

Accepted Answer

A)  3 Na+ ions are pumped into the cell with 2 K+ ions being pumped out 
B)  3 Na+ ions move in and 1 Ca2+ ion moves out 
C)  1 Na+ ion m ov es ou t with eve y K+ ion tha t moves in 
D)  3 Na+ ions are pumped out of the cell with 2 K+ ion s be ing pu m pe d in 
E)  3 Na+ ions are pumped out of the cell with each K+ ion being 
pumped in 
A)  3 Na+ ions are pumped into the cell with 2 K+ ions being pumped out 
B)  3 Na+ ions move in and 1 Ca2+ ion moves out 
C)  1 Na+ ion m ov es ou t with eve y K+ ion tha t moves in 
D)  3 Na+ ions are pumped out of the cell with 2 K+ ion s be ing pu m pe d in 
E)  3 Na+ ions are pumped out of the cell with each K+ ion being 
pumped in D

Question 2

Primary active transport mechanisms

Accepted Answer

A)  Use the energy of the Na+ grad ient to power "up hill" transport of another solute 
B)  Hydrolyze ATP 
C)  Are facilitated diffusion mechanisms 
D)  Cannot concentrate solutes 
E)  Transport only ions 
A)  Use the energy of the Na+ grad ient to power "up hill" transport of another solute 
B)  Hydrolyze ATP 
C)  Are facilitated diffusion mechanisms 
D)  Cannot concentrate solutes 
E)  Transport only ions B

Question 3

Secondary active transport mechanisms

Accepted Answer

A)  Hydrolyze ATP 
B)  Couple movement of one material down its electrochemical gradient with another solute moving up its electrochemical gradient 
C)  Cannot concentrate solutes 
D)  Are facilitated diffusion mechanisms 
E)  Are not saturable 
A)  Hydrolyze ATP 
B)  Couple movement of one material down its electrochemical gradient with another solute moving up its electrochemical gradient 
C)  Cannot concentrate solutes 
D)  Are facilitated diffusion mechanisms 
E)  Are not saturable B

Question 4

For most cells in the body, the intracellular [Na+] is about

Accepted Answer

A)  290 mM 
B)  145 mM 
C)  60 mM 
D)  12 mM 
E)  4 mM 
A)  290 mM 
B)  145 mM 
C)  60 mM 
D)  12 mM 
E)  4 mM

Question 5

Active transport differs from passive transport in that

Accepted Answer

A)  Active transport is saturable where as passive transport is not saturable 
B)  Active transport requires metabolic energy whereas passive transport does not 
C)  Active transport displays competition whereas passive transport does not 
D)  Active transport moves things from high to low electrochemical potential whereas passive transport moves them the other way 
E)  Active transport involves proteins, whereas passive transport does not 
A)  Active transport is saturable where as passive transport is not saturable 
B)  Active transport requires metabolic energy whereas passive transport does not 
C)  Active transport displays competition whereas passive transport does not 
D)  Active transport moves things from high to low electrochemical potential whereas passive transport moves them the other way 
E)  Active transport involves proteins, whereas passive transport does not

Question 6

The stoichiometry of the NCX is

Accepted Answer

A)  3 Na+ ions for every Ca2+ ion 
B)  2 Na+ ions for every Ca2+ ion 
C)  1 Na+ ion for every Ca2+ ion 
D)  3 Na+ ions for every 2 Ca2+ ions 
E)  2 Na+ ions for every 2 Ca2+ ions 
A)  3 Na+ ions for every Ca2+ ion 
B)  2 Na+ ions for every Ca2+ ion 
C)  1 Na+ ion for every Ca2+ ion 
D)  3 Na+ ions for every 2 Ca2+ ions 
E)  2 Na+ ions for every 2 Ca2+ ions

Question 7

The electrochemical potential for an ion in solution is given as

Accepted Answer

A)  $ \mu=R T \ln C+Z \mathfrak{S} \Psi $ 
B)  $ \mu=\mu^{0}+R T C+z \Im \Psi $ 
C)  $ \mu=\Delta \mu^{0}+R T \Delta C+Z \mathfrak{S} \Delta \Psi $ 
D)  $ \mu=\mu^{0}+\mathrm{RT} \ln \mathrm{C}+\mathbf{z} \mathfrak{S} \Psi $ 
E)  $ \mu=-R T \ln K_{e q} $ 
A)  $ \mu=R T \ln C+Z \mathfrak{S} \Psi $ 
B)  $ \mu=\mu^{0}+R T C+z \Im \Psi $ 
C)  $ \mu=\Delta \mu^{0}+R T \Delta C+Z \mathfrak{S} \Delta \Psi $ 
D)  $ \mu=\mu^{0}+\mathrm{RT} \ln \mathrm{C}+\mathbf{z} \mathfrak{S} \Psi $ 
E)  $ \mu=-R T \ln K_{e q} $

Question 8

Which of the following is a secondary active transport mechanism?

Accepted Answer

A)  Na,K-ATPase 
B)  PMCA 
C)  NCX 
D)  SPCA 
E)  SERCA 
A)  Na,K-ATPase 
B)  PMCA 
C)  NCX 
D)  SPCA 
E)  SERCA

Question 9

Active Transport mechanisms

Accepted Answer

A)  Equilibrate the concentration of a solute across a mem brane 
B)  Move at least one substrate from a region of lower electrochemical potential to a region of higher electrochemical potential 
C)  Do not respond to differences in potential across a membrane 
D)  Move only ions 
E)  Do not require metabolic energy 
A)  Equilibrate the concentration of a solute across a mem brane 
B)  Move at least one substrate from a region of lower electrochemical potential to a region of higher electrochemical potential 
C)  Do not respond to differences in potential across a membrane 
D)  Move only ions 
E)  Do not require metabolic energy

Question 10

A symport is a transport mechanism that

Accepted Answer

A)  Transports ions across the symphysis 
B)  Transports two solutes in the same direction 
C)  Transports one solute down its electrochemical gradient 
D)  Transports two solutes in opposite directions 
E)  Transports one solute up its electrochemical gradient 
A)  Transports ions across the symphysis 
B)  Transports two solutes in the same direction 
C)  Transports one solute down its electrochemical gradient 
D)  Transports two solutes in opposite directions 
E)  Transports one solute up its electrochemical gradient

Question 11

An example of a primary active transport mechanism is

Accepted Answer

A)  SGLT-1 
B)  NHE 
C)  NCX 
D)  SERCA 
E)  NIS 
A)  SGLT-1 
B)  NHE 
C)  NCX 
D)  SERCA 
E)  NIS

Question 12

For most cells in the body, the extracellular [Na+] is about

Accepted Answer

A)  290 mM 
B)  145 mM 
C)  60 mM 
D)  12 mM 
E)  4 mM 
A)  290 mM 
B)  145 mM 
C)  60 mM 
D)  12 mM 
E)  4 mM

Question 13

Which of the following does NOT work through a primary active transport mechanism?

Accepted Answer

A)  SERCA 
B)  Na,K-ATPase 
C)  PMCA 
D)  SG LT -1 
E)  H-K-ATPase 
A)  SERCA 
B)  Na,K-ATPase 
C)  PMCA 
D)  SG LT -1 
E)  H-K-ATPase

Question 14

For most cells in the body, the intracellular free [Ca2+] is about

Accepted Answer

A)  12 mM 
B)  1.2 mM 
C)  0.12 mM 
D)  10.2 µM 
E)  Less than 1µ M 
A)  12 mM 
B)  1.2 mM 
C)  0.12 mM 
D)  10.2 µM 
E)  Less than 1µ M

Question 15

An example of a symport is

Accepted Answer

A)  SGLT1 
B)  NCX 
C)  NHE 
D)  AE 
E)  Na,K-ATPase 
A)  SGLT1 
B)  NCX 
C)  NHE 
D)  AE 
E)  Na,K-ATPase

Question 16

Which of the following is NOT a secondary active transport mechanism?

Accepted Answer

A)  H,K-ATPase 
B)  SGLT-1 
C)  NCX 
D)  NIS 
E)  NHE 
A)  H,K-ATPase 
B)  SGLT-1 
C)  NCX 
D)  NIS 
E)  NHE

Exam 11: Active Transport: Pumps and Exchangers

The stoichiometry of the Na ,K- AT Pase is

Primary active transport mechanisms

Secondary active transport mechanisms

For most cells in the body, the intracellular [Na+] is about

Active transport differs from passive transport in that

The stoichiometry of the NCX is

The electrochemical potential for an ion in solution is given as

Which of the following is a secondary active transport mechanism?

Active Transport mechanisms

A symport is a transport mechanism that

An example of a primary active transport mechanism is

For most cells in the body, the extracellular [Na+] is about

Which of the following does NOT work through a primary active transport mechanism?

For most cells in the body, the intracellular free [Ca2+] is about

An example of a symport is

Which of the following is NOT a secondary active transport mechanism?

Physical Foundations Ii: Electrical Force Potential Capacitance and Current

Chemical Foundations I: Chemical Energy and Intermolecular Forces

Chemical Foundations Ii: Concentration and Kinetics

Diffusion

Electrochemical Potential and Free Energy

Cell Structure

Dna and Protein Synthesis

Protein Structure

Biological Membranes

Passive Transport and Facilitated Diffusion

Osmosis and Osmotic Pressure

Cell Signaling

ATP Production I: Glycolysis

Atp Production Ii: Tca Cycle and Oxidative Phosphorylation

Atp Production Iii: Fatty Acid Oxidation and Amino Acid Oxidation

Origin of the Membrane Potential

The Action Potential

Propagation of the Action Potential

Skeletal Muscle Mechanics

Contractile Mechanisms in Skeletal Muscle

Neuromuscular Junction and Ec Coupling

Muscle Energetics Fatigue and Training

Smooth Muscle

Organization of the Nervous System

Cells Synapses and Neurotransmitters

Cutaneous Sensory Systems

Spinal Reflexes

Balance and Control of Movement

the Chemical Senses

Hearing

Vision

Autonomic Nervous System

Overview of the Cv System and Blood

Plasma and Red Blood Cells

White Blood Cells and Inflammation

The Heart As a Pump

Cellular Basis of Cardiac Contractility

the Cardiac Function Curve

Vascular Function: Hemodynamics

Microcirculation and Solute Exchange

Regulation of Perfusion

Integration of Cardiac Output and Venous Return

Regulation of Arterial Pressure

Mechanics of Breathing

Lung Volumes and Airway Resistance

Gas Exchange in the Lung

Oxygen and Carbon Dioxide Transport

Acid Base Physiology I Bicarbonate Buffers and Respiratory Compensation

Control of Ventilation

Anatomy and Renal Overview

Glomerular Filtration

Tubular Reabsorption and Secretion

Concentration and Dilution of Urine

Mouth and Esophagus

The Stomach

Intestinal and Colonic Motility

Pancreatic and Biliary Secretion

Digestion and Absorption of the Macronutrients

Energy Balance and Regulation of Food Intake

General Principles of Endocrinology

Hypothalamus and Pituitary Gland

The Thyroid Gland

The Endocrine Pancreas

For most cells in the body, the intracellular [Na⁺] is about

For most cells in the body, the extracellular [Na⁺] is about

For most cells in the body, the intracellular free [Ca²⁺] is about