Deck 22: Population and Evolutionary Genetics

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Question
The discipline within evolutionary biology that studies changes in allele frequencies is known as ________.

A)population genetics
B)consanguinity
C)hybrid vigor
D)genetics
E)cytogenetics
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Question
What is meant by the equation p + q = 1.0?
Question
List at least three factors that change gene frequencies in populations.
Question
A certain form of albinism in humans is recessive and autosomal.Assume that 1 percent of the individuals in a given population are albino.Assuming that the population is in Hardy-Weinberg equilibrium,what percentage of the individuals in this population are expected to be heterozygous?
Question
What does the variable 2pq represent?
Question
A number of mechanisms operate to maintain genetic diversity in a population.Why is such diversity favored?

A)Homozygosity is an evolutionary advantage.
B)Diversity leads to inbreeding advantages.
C)Genetic diversity may better adapt a population to inevitable changes in the environment.
D)Greater genetic diversity increases the chances of haploidy.
E)Genetic diversity helps populations avoid diploidy.
Question
Which term is given to the total genetic information carried by all members of a population?

A)gene pool
B)genome
C)chromosome complement
D)breeding unit
E)race
Question
Which method is often used to analyze proteins and nucleic acids by physical separation when estimating genetic variation in populations?

A)electrophoresis
B)centrifugation
C)absorption spectrophotometry
D)fluorometry
E)in situ hybridization
Question
Which general term is used to group various biological and behavioral properties of organisms that act to prevent or reduce interbreeding?

A)phyletic evolution
B)allopatric speciation
C)reproductive isolating mechanisms
D)inbreeding
E)genetic divergence
Question
In a population of 10,000 individuals,in which 3600 are MM,1600 are NN,and 4800 are MN,what are the frequencies of the M alleles and the N alleles?
Question
In a population that meets the Hardy-Weinberg equilibrium assumptions,81 percent of the individuals are homozygous for a recessive allele.What percentage of the individuals would be expected to be heterozygous for this locus in the next generation?
Question
In small isolated populations,gene frequencies can fluctuate considerably.The term that applies to this circumstance is ________.

A)genetic isolation
B)allelic separation
C)natural selection
D)stabilizing selection
E)genetic drift
Question
In a population of 100 individuals,49 percent are of the NN blood type.What percentage is expected to be MN assuming Hardy-Weinberg equilibrium conditions?

A)9 percent
B)21 percent
C)42 percent
D)51 percent
E)There is insufficient information to answer this question.
Question
In a population of cattle,the following color distribution was noted: 36 percent red (RR),48 percent roan (Rr),and 16 percent white (rr).Is this population in a Hardy-Weinberg equilibrium? What will be the distribution of genotypes in the next generation if the Hardy-Weinberg assumptions are met?
Question
Assuming that p = 0.3 for a population in Hardy-Weinberg equilibrium,what would be the expected frequency of heterozygotes for the involved allelic pair?
Question
Albinism is an autosomal recessive trait in humans.Assume that there are 100 albinos (aa)in a population of 1 million.How many individuals would be expected to be homozygous normal (AA)under equilibrium conditions?

A)100
B)10,000
C)19,800
D)980,100
E)999,900
Question
Assume that in a Hardy-Weinberg population,9 percent of the individuals are of the homozygous recessive phenotype.What percentage are homozygous dominant?
Question
List at least five of the assumptions that pertain to a population in a Hardy-Weinberg equilibrium.
Question
Briefly define the term genetic equilibrium.
Question
Assume that a trait is caused by the homozygous state of a gene that is recessive and autosomal.Nine percent of the individuals in a given population express the phenotype caused by this gene.What percentage of the individuals would be heterozygous for the gene? Assume that the population is in Hardy-Weinberg equilibrium.
Question
Contrast directional and stabilizing forms of selection.
Question
Mutation and migration introduce new alleles into populations.What is the most likely principal force that will shift allelic frequencies within large populations?
Question
Migration occurs when individuals move between populations.Considering a single pair of alleles,A and a,which formula is used to indicate the new frequency of A in one generation of migration?
Question
What is the original source of genetic variation in a population? Which natural factors affect changes in this original variation?
Question
Which term is given to the measure of the proportion of offspring that a particular phenotype will contribute to the next generation?
Question
One of the Hardy-Weinberg assumptions states that the population is infinitely large.What influence might a small population size have on a Hardy-Weinberg equilibrium?
Question
What type of evolutionary information can be gained by examining the amino acid sequence of a protein such as cytochrome c?
Question
In zoo animals,inbreeding often occurs because of a lack of a sufficient pool of breeding individuals.Under such conditions,which two characteristics are often exhibited among inbred organisms?
Question
Which would change allele frequencies more quickly: selection against a dominant allele or selection against a recessive allele?
Question
The difference between fitness of a given genotype and another genotype considered optimal is called the selection coefficient (s).What is the selection coefficient for a genotype (aa)that produces an average of 99 offspring when Aa individuals produce an average of 100 offspring?
Question
Define the term speciation.
Question
Suppose that a given gene undergoes a mutation to a dominant allele such that 2 out of 100,000 offspring exhibit the new mutant phenotype.Assuming that these offspring are heterozygous,what is the mutation rate for the gene?
Question
Present a rationale for using DNA sequence polymorphisms as an index of genetic diversity.Is genetic diversity directly proportional to evolutionary (phylogenetic)diversity?
Question
Why is mitochondrial DNA often used in construction of phylogenetic trees?
Question
One of the Hardy-Weinberg assumptions states that all genotypes in the population are free of selective advantage.What influence might a selective advantage of a genotype have on a Hardy-Weinberg equilibrium?
Question
Which single event is probably common to all occurrences of speciation?
Question
Why are some proteins more likely than others to diverge within a species?
Question
What are the genetic consequences of inbreeding?
Question
List and briefly describe three factors that contribute to the phenomenon of natural selection.
Question
Define the term fitness and relate it to the meaning of selection coefficient.
Question
If a gene has three alleles in a population,their frequencies must add up to 1.5.
Question
Natural selection occurs when there is nonrandom elimination of genotypes from a population due to differences in viability or reproductive success.
Question
In the case of complete dominance in a population in equilibrium,we cannot tell which individuals are homozygous dominants and which are heterozygous,but by knowing the frequency of the homozygous recessives,we can estimate the frequency of homozygous dominant and heterozygous genotypes.
Question
Genetic drift is primarily associated with relatively small breeding populations.
Question
Selection is the differential reproduction of genotypes,resulting from their variable fitness.
Question
Given an inheritance pattern of incomplete dominance and 81 flowers that are red (R¹?¹),18 flowers that are pink (R¹?²),and 1 flower that is white (R²?²),the frequency of the R¹ allele is 0.9.
Question
Would one expect a linear relationship between DNA sequence divergence and phylogenetic distance? Why or why not?
Question
Inbreeding by itself can change gene frequencies.
Question
Conservation of amino acid sequence among distantly related groups of organisms is suggestive of an important function of that sequence.
Question
Cytochrome c is a respiratory pigment found in the mitochondria of eukaryotes.Compared with some other proteins,it has changed very slowly over long periods of time.Why?
Question
In large random mating populations,random genetic drift is usually a significant factor in changing gene frequencies.
Question
In an evolutionary sense,what is meant by the term molecular clock?
Question
For a given locus,in a population with two alternative alleles,the allele frequencies
p + q = 1.0.
Question
Evolution is dependent on genetic diversity in the evolving population.
Question
In directional selection,both phenotypic extremes are equally selected against.
Question
What are phylogenetic trees?
Question
What information have the results of mitochondrial DNA analysis offered concerning the phylogenetic relationships between Neanderthals and modern humans?
Question
Mutations are regarded as a strong evolutionary mechanism for changing allelic frequencies.
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Deck 22: Population and Evolutionary Genetics
1
The discipline within evolutionary biology that studies changes in allele frequencies is known as ________.

A)population genetics
B)consanguinity
C)hybrid vigor
D)genetics
E)cytogenetics
A
2
What is meant by the equation p + q = 1.0?
The sum of the relevant individual alleles in a population is equal to 100 percent of those alleles.
3
List at least three factors that change gene frequencies in populations.
mutation,migration,selection,genetic drift
4
A certain form of albinism in humans is recessive and autosomal.Assume that 1 percent of the individuals in a given population are albino.Assuming that the population is in Hardy-Weinberg equilibrium,what percentage of the individuals in this population are expected to be heterozygous?
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5
What does the variable 2pq represent?
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Unlock Deck
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6
A number of mechanisms operate to maintain genetic diversity in a population.Why is such diversity favored?

A)Homozygosity is an evolutionary advantage.
B)Diversity leads to inbreeding advantages.
C)Genetic diversity may better adapt a population to inevitable changes in the environment.
D)Greater genetic diversity increases the chances of haploidy.
E)Genetic diversity helps populations avoid diploidy.
Unlock Deck
Unlock for access to all 58 flashcards in this deck.
Unlock Deck
k this deck
7
Which term is given to the total genetic information carried by all members of a population?

A)gene pool
B)genome
C)chromosome complement
D)breeding unit
E)race
Unlock Deck
Unlock for access to all 58 flashcards in this deck.
Unlock Deck
k this deck
8
Which method is often used to analyze proteins and nucleic acids by physical separation when estimating genetic variation in populations?

A)electrophoresis
B)centrifugation
C)absorption spectrophotometry
D)fluorometry
E)in situ hybridization
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Unlock for access to all 58 flashcards in this deck.
Unlock Deck
k this deck
9
Which general term is used to group various biological and behavioral properties of organisms that act to prevent or reduce interbreeding?

A)phyletic evolution
B)allopatric speciation
C)reproductive isolating mechanisms
D)inbreeding
E)genetic divergence
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Unlock for access to all 58 flashcards in this deck.
Unlock Deck
k this deck
10
In a population of 10,000 individuals,in which 3600 are MM,1600 are NN,and 4800 are MN,what are the frequencies of the M alleles and the N alleles?
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11
In a population that meets the Hardy-Weinberg equilibrium assumptions,81 percent of the individuals are homozygous for a recessive allele.What percentage of the individuals would be expected to be heterozygous for this locus in the next generation?
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Unlock for access to all 58 flashcards in this deck.
Unlock Deck
k this deck
12
In small isolated populations,gene frequencies can fluctuate considerably.The term that applies to this circumstance is ________.

A)genetic isolation
B)allelic separation
C)natural selection
D)stabilizing selection
E)genetic drift
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Unlock for access to all 58 flashcards in this deck.
Unlock Deck
k this deck
13
In a population of 100 individuals,49 percent are of the NN blood type.What percentage is expected to be MN assuming Hardy-Weinberg equilibrium conditions?

A)9 percent
B)21 percent
C)42 percent
D)51 percent
E)There is insufficient information to answer this question.
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Unlock for access to all 58 flashcards in this deck.
Unlock Deck
k this deck
14
In a population of cattle,the following color distribution was noted: 36 percent red (RR),48 percent roan (Rr),and 16 percent white (rr).Is this population in a Hardy-Weinberg equilibrium? What will be the distribution of genotypes in the next generation if the Hardy-Weinberg assumptions are met?
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Unlock for access to all 58 flashcards in this deck.
Unlock Deck
k this deck
15
Assuming that p = 0.3 for a population in Hardy-Weinberg equilibrium,what would be the expected frequency of heterozygotes for the involved allelic pair?
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Unlock for access to all 58 flashcards in this deck.
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k this deck
16
Albinism is an autosomal recessive trait in humans.Assume that there are 100 albinos (aa)in a population of 1 million.How many individuals would be expected to be homozygous normal (AA)under equilibrium conditions?

A)100
B)10,000
C)19,800
D)980,100
E)999,900
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k this deck
17
Assume that in a Hardy-Weinberg population,9 percent of the individuals are of the homozygous recessive phenotype.What percentage are homozygous dominant?
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18
List at least five of the assumptions that pertain to a population in a Hardy-Weinberg equilibrium.
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19
Briefly define the term genetic equilibrium.
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20
Assume that a trait is caused by the homozygous state of a gene that is recessive and autosomal.Nine percent of the individuals in a given population express the phenotype caused by this gene.What percentage of the individuals would be heterozygous for the gene? Assume that the population is in Hardy-Weinberg equilibrium.
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21
Contrast directional and stabilizing forms of selection.
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22
Mutation and migration introduce new alleles into populations.What is the most likely principal force that will shift allelic frequencies within large populations?
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Unlock for access to all 58 flashcards in this deck.
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k this deck
23
Migration occurs when individuals move between populations.Considering a single pair of alleles,A and a,which formula is used to indicate the new frequency of A in one generation of migration?
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k this deck
24
What is the original source of genetic variation in a population? Which natural factors affect changes in this original variation?
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k this deck
25
Which term is given to the measure of the proportion of offspring that a particular phenotype will contribute to the next generation?
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k this deck
26
One of the Hardy-Weinberg assumptions states that the population is infinitely large.What influence might a small population size have on a Hardy-Weinberg equilibrium?
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k this deck
27
What type of evolutionary information can be gained by examining the amino acid sequence of a protein such as cytochrome c?
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Unlock for access to all 58 flashcards in this deck.
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k this deck
28
In zoo animals,inbreeding often occurs because of a lack of a sufficient pool of breeding individuals.Under such conditions,which two characteristics are often exhibited among inbred organisms?
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k this deck
29
Which would change allele frequencies more quickly: selection against a dominant allele or selection against a recessive allele?
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30
The difference between fitness of a given genotype and another genotype considered optimal is called the selection coefficient (s).What is the selection coefficient for a genotype (aa)that produces an average of 99 offspring when Aa individuals produce an average of 100 offspring?
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31
Define the term speciation.
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32
Suppose that a given gene undergoes a mutation to a dominant allele such that 2 out of 100,000 offspring exhibit the new mutant phenotype.Assuming that these offspring are heterozygous,what is the mutation rate for the gene?
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33
Present a rationale for using DNA sequence polymorphisms as an index of genetic diversity.Is genetic diversity directly proportional to evolutionary (phylogenetic)diversity?
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34
Why is mitochondrial DNA often used in construction of phylogenetic trees?
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35
One of the Hardy-Weinberg assumptions states that all genotypes in the population are free of selective advantage.What influence might a selective advantage of a genotype have on a Hardy-Weinberg equilibrium?
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36
Which single event is probably common to all occurrences of speciation?
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37
Why are some proteins more likely than others to diverge within a species?
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38
What are the genetic consequences of inbreeding?
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39
List and briefly describe three factors that contribute to the phenomenon of natural selection.
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40
Define the term fitness and relate it to the meaning of selection coefficient.
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41
If a gene has three alleles in a population,their frequencies must add up to 1.5.
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42
Natural selection occurs when there is nonrandom elimination of genotypes from a population due to differences in viability or reproductive success.
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k this deck
43
In the case of complete dominance in a population in equilibrium,we cannot tell which individuals are homozygous dominants and which are heterozygous,but by knowing the frequency of the homozygous recessives,we can estimate the frequency of homozygous dominant and heterozygous genotypes.
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k this deck
44
Genetic drift is primarily associated with relatively small breeding populations.
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k this deck
45
Selection is the differential reproduction of genotypes,resulting from their variable fitness.
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k this deck
46
Given an inheritance pattern of incomplete dominance and 81 flowers that are red (R¹?¹),18 flowers that are pink (R¹?²),and 1 flower that is white (R²?²),the frequency of the R¹ allele is 0.9.
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47
Would one expect a linear relationship between DNA sequence divergence and phylogenetic distance? Why or why not?
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48
Inbreeding by itself can change gene frequencies.
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49
Conservation of amino acid sequence among distantly related groups of organisms is suggestive of an important function of that sequence.
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Unlock for access to all 58 flashcards in this deck.
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k this deck
50
Cytochrome c is a respiratory pigment found in the mitochondria of eukaryotes.Compared with some other proteins,it has changed very slowly over long periods of time.Why?
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k this deck
51
In large random mating populations,random genetic drift is usually a significant factor in changing gene frequencies.
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k this deck
52
In an evolutionary sense,what is meant by the term molecular clock?
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k this deck
53
For a given locus,in a population with two alternative alleles,the allele frequencies
p + q = 1.0.
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k this deck
54
Evolution is dependent on genetic diversity in the evolving population.
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k this deck
55
In directional selection,both phenotypic extremes are equally selected against.
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56
What are phylogenetic trees?
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57
What information have the results of mitochondrial DNA analysis offered concerning the phylogenetic relationships between Neanderthals and modern humans?
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58
Mutations are regarded as a strong evolutionary mechanism for changing allelic frequencies.
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