Exam 22: Population and Evolutionary Genetics

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Define the term fitness and relate it to the meaning of selection coefficient.

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Fitness is a measure of the proportion of offspring that a particular phenotype will contribute to the next generation; the selection coefficient is the mathematical difference between the actual fitness of a given genotype and the optimal fitness for an individual in a given population.

What is the original source of genetic variation in a population? Which natural factors affect changes in this original variation?

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Mutation is the original source.Chromosomal assortment and crossing over reshuffle combinations of mutations at different loci; forces such as selection,genetic drift,and migration can increase or decrease the frequencies of mutant alleles in populations.

Assuming that p = 0.3 for a population in Hardy-Weinberg equilibrium,what would be the expected frequency of heterozygotes for the involved allelic pair?

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0.42

Assume that a trait is caused by the homozygous state of a gene that is recessive and autosomal.Nine percent of the individuals in a given population express the phenotype caused by this gene.What percentage of the individuals would be heterozygous for the gene? Assume that the population is in Hardy-Weinberg equilibrium.

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Which would change allele frequencies more quickly: selection against a dominant allele or selection against a recessive allele?

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In small isolated populations,gene frequencies can fluctuate considerably.The term that applies to this circumstance is ________.

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List at least five of the assumptions that pertain to a population in a Hardy-Weinberg equilibrium.

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For a given locus,in a population with two alternative alleles,the allele frequencies p + q = 1.0.

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Contrast directional and stabilizing forms of selection.

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A certain form of albinism in humans is recessive and autosomal.Assume that 1 percent of the individuals in a given population are albino.Assuming that the population is in Hardy-Weinberg equilibrium,what percentage of the individuals in this population are expected to be heterozygous?

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List at least three factors that change gene frequencies in populations.

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In a population of 100 individuals,49 percent are of the NN blood type.What percentage is expected to be MN assuming Hardy-Weinberg equilibrium conditions?

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Genetic drift is primarily associated with relatively small breeding populations.

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Present a rationale for using DNA sequence polymorphisms as an index of genetic diversity.Is genetic diversity directly proportional to evolutionary (phylogenetic)diversity?

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Which single event is probably common to all occurrences of speciation?

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In a population of cattle,the following color distribution was noted: 36 percent red (RR),48 percent roan (Rr),and 16 percent white (rr).Is this population in a Hardy-Weinberg equilibrium? What will be the distribution of genotypes in the next generation if the Hardy-Weinberg assumptions are met?

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List and briefly describe three factors that contribute to the phenomenon of natural selection.

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Evolution is dependent on genetic diversity in the evolving population.

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Migration occurs when individuals move between populations.Considering a single pair of alleles,A and a,which formula is used to indicate the new frequency of A in one generation of migration?

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Which method is often used to analyze proteins and nucleic acids by physical separation when estimating genetic variation in populations?

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