Deck 2: Functional Neuroanatomy: The Cells and Structures of the Nervous System
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Deck 2: Functional Neuroanatomy: The Cells and Structures of the Nervous System
1
Which histological technique is used for tract tracing?
A) labeled pseudorabies virus
B) In situ hybridization
C) Golgi stain
D) Nissl stain
A) labeled pseudorabies virus
B) In situ hybridization
C) Golgi stain
D) Nissl stain
A
2
The adult human brain contains
A) 100‒150 billion circuits.
B) 80‒90 billion neurons.
C) 100‒150 million neurons.
D) 100‒150 million glial cells.
A) 100‒150 billion circuits.
B) 80‒90 billion neurons.
C) 100‒150 million neurons.
D) 100‒150 million glial cells.
B
3
The neuron doctrine
A) was confirmed using electron microscopy.
B) proposed the existence of synaptic contacts between neurons.
C) stemmed from the work of the great neuroanatomist Ramón y Cajal.
D) All of the above
A) was confirmed using electron microscopy.
B) proposed the existence of synaptic contacts between neurons.
C) stemmed from the work of the great neuroanatomist Ramón y Cajal.
D) All of the above
D
4
The "giant" axons of some invertebrate animals can have diameters as large as
A) 20 m.
B) 1 mm.
C) 500 m.
D) 20 nm.
A) 20 m.
B) 1 mm.
C) 500 m.
D) 20 nm.
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5
Which statement does not describe a reason that tract-tracing studies have been difficult to perform?
A) Fibers with different destinations often travel together.
B) Axons have very small diameters and therefore are hard to see.
C) Axons from different sources look alike.
D) All of the above are reasons for the difficulty.
A) Fibers with different destinations often travel together.
B) Axons have very small diameters and therefore are hard to see.
C) Axons from different sources look alike.
D) All of the above are reasons for the difficulty.
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6
The size range of most nerve cell bodies is
A) 1‒10 m.
B) 1‒10 mm.
C) 10‒100 nm.
D) 10‒100 m.
A) 1‒10 m.
B) 1‒10 mm.
C) 10‒100 nm.
D) 10‒100 m.
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7
The range of diameters of mammalian axons is
A) 1‒10 mm.
B) 0.2‒20 m.
C) 0.05‒2.0 m.
D) 100‒300 m.
A) 1‒10 mm.
B) 0.2‒20 m.
C) 0.05‒2.0 m.
D) 100‒300 m.
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8
In which way(s) are dendrites and axons similar?
A) Both are characterized by branching.
B) They have similar lengths.
C) Both exhibit a tapering of diameter with increasing distance from the cell body.
D) All of the above
A) Both are characterized by branching.
B) They have similar lengths.
C) Both exhibit a tapering of diameter with increasing distance from the cell body.
D) All of the above
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9
Dendrites are
A) a type of glial cell.
B) the input zone of a nerve cell.
C) the output zone of a nerve cell.
D) small cerebellar neurons.
A) a type of glial cell.
B) the input zone of a nerve cell.
C) the output zone of a nerve cell.
D) small cerebellar neurons.
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10
The "slow" rate of axonal transport is
A) 400 mm/day.
B) 1 m/day.
C) less than 8 mm/day.
D) 40 mm/day.
A) 400 mm/day.
B) 1 m/day.
C) less than 8 mm/day.
D) 40 mm/day.
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11
Which statement about dendritic spines is true?
A) Alzheimer's disease is associated with a pathological change in dendritic spines.
B) Dendritic spines are outgrowths on the surface of dendrites that are modified by experience.
C) Dendritic spines are neuronal structures found along the axon.
D) Only the structure of dendritic spines can be altered by experience.
A) Alzheimer's disease is associated with a pathological change in dendritic spines.
B) Dendritic spines are outgrowths on the surface of dendrites that are modified by experience.
C) Dendritic spines are neuronal structures found along the axon.
D) Only the structure of dendritic spines can be altered by experience.
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12
Which statement about dendrites is false?
A) A single cell's dendrites form a dendritic tree.
B) The diversity of neuronal shapes is caused primarily by variation in the form and shape of dendrites.
C) Dendrites may be several meters in length in giraffes.
D) Dendritic spines appear to be subject to modification as a result of experience.
A) A single cell's dendrites form a dendritic tree.
B) The diversity of neuronal shapes is caused primarily by variation in the form and shape of dendrites.
C) Dendrites may be several meters in length in giraffes.
D) Dendritic spines appear to be subject to modification as a result of experience.
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13
Substances are conveyed from the cell body of the neuron to the distant reaches of the axon through the process of
A) innervation.
B) axonal transport.
C) neurotransmission.
D) conduction.
A) innervation.
B) axonal transport.
C) neurotransmission.
D) conduction.
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14
Although nerve cells typically have only one axon, an axon may divide into numerous axon
A) hillocks.
B) receptors.
C) conduction zones.
D) collaterals.
A) hillocks.
B) receptors.
C) conduction zones.
D) collaterals.
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15
Which neurons can collect the most information?
A) Bipolar
B) Monopolar
C) Multipolar
D) Unipolar
A) Bipolar
B) Monopolar
C) Multipolar
D) Unipolar
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16
Every neuron has all of these components except
A) myelin.
B) dendrites.
C) axons.
D) a nucleus.
A) myelin.
B) dendrites.
C) axons.
D) a nucleus.
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17
Most neurons
A) receive input related to changes in the environment.
B) are classified as motoneurons.
C) are classified as sensory neurons.
D) are classified as interneurons.
A) receive input related to changes in the environment.
B) are classified as motoneurons.
C) are classified as sensory neurons.
D) are classified as interneurons.
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18
Synaptic vesicles are found in the
A) cell body.
B) dendritic spines.
C) axon hillock.
D) synaptic boutons.
A) cell body.
B) dendritic spines.
C) axon hillock.
D) synaptic boutons.
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19
Axon terminals form the _______ side of a synapse, and dendrites form the _______ side of a synapse.
A) presynaptic; postsynaptic
B) input; output
C) postsynaptic; presynaptic
D) conduction; integration
A) presynaptic; postsynaptic
B) input; output
C) postsynaptic; presynaptic
D) conduction; integration
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20
The gaps between segments of myelin are known as
A) synaptic clefts.
B) nodes of Ranvier.
C) terminal boutons.
D) neuromuscular junctions.
A) synaptic clefts.
B) nodes of Ranvier.
C) terminal boutons.
D) neuromuscular junctions.
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21
The width of the synaptic cleft is about
A) 200 nm.
B) 200 m.
C) 20 m.
D) 20 nm.
A) 200 nm.
B) 200 m.
C) 20 m.
D) 20 nm.
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22
Synaptic boutons are
A) found within synaptic vesicles.
B) protrusions occurring along the length of dendrites.
C) swellings found at axon terminals.
D) specialized synapses occurring on muscles.
A) found within synaptic vesicles.
B) protrusions occurring along the length of dendrites.
C) swellings found at axon terminals.
D) specialized synapses occurring on muscles.
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23
The electrical impulse that stimulates neurotransmitter release, thereby transmitting information to other neurons, arises in the
A) dendrites.
B) axon hillock.
C) axon.
D) dendritic spine.
A) dendrites.
B) axon hillock.
C) axon.
D) dendritic spine.
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24
The two major cell types that make up the nervous system are _______ cells and _______.
A) mitochondria; ribosomes
B) collateral; terminals
C) glial; neurons
D) axons; dendrites
A) mitochondria; ribosomes
B) collateral; terminals
C) glial; neurons
D) axons; dendrites
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25
The major function of Schwann cells is the
A) transmission of nutrients to neurons.
B) myelination of peripheral nerve fibers.
C) scavenging of cellular debris.
D) myelination of axons in the brain.
A) transmission of nutrients to neurons.
B) myelination of peripheral nerve fibers.
C) scavenging of cellular debris.
D) myelination of axons in the brain.
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26
In the disease multiple sclerosis, myelin in the brain is lost. Which cells are responsible for myelination in the brain?
A) Oligodendrocytes
B) Schwann cells
C) Astrocytes
D) Both a and b
A) Oligodendrocytes
B) Schwann cells
C) Astrocytes
D) Both a and b
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27
Which type of cells give rise to brain tumors?
A) Pyramidal cells
B) Multipolar cells
C) Glial cells
D) Granule cells
A) Pyramidal cells
B) Multipolar cells
C) Glial cells
D) Granule cells
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28
Which glial cells have sucker-like extensions that contact blood vessels?
A) Oligodendrocytes
B) Astrocytes
C) Microglial cells
D) Stellate cells
A) Oligodendrocytes
B) Astrocytes
C) Microglial cells
D) Stellate cells
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29
Fibers that carry information away from the brain are called _______, whereas fibers that carry information toward the brain are called _______.
A) efferents; afferents
B) output zones; input zones
C) cranial nerves; spinal nerves
D) sensory nerves; motor nerves
A) efferents; afferents
B) output zones; input zones
C) cranial nerves; spinal nerves
D) sensory nerves; motor nerves
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30
The three main components of the peripheral nervous system are the _______ nerves, the _______ nerves, and the _______ nervous system.
A) frontal, parietal, and temporal
B) cranial, spinal, autonomic
C) motor; somatic, sensory
D) central, peripheral, autonomic
A) frontal, parietal, and temporal
B) cranial, spinal, autonomic
C) motor; somatic, sensory
D) central, peripheral, autonomic
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31
Which three cranial nerves are involved in the control of eye movements?
A) Oculomotor, trochlear, vagus
B) Oculomotor, trochlear, abducens
C) Trochlear, abducens, vagus
D) Abducens, oculomotor, vagus
A) Oculomotor, trochlear, vagus
B) Oculomotor, trochlear, abducens
C) Trochlear, abducens, vagus
D) Abducens, oculomotor, vagus
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32
How many pairs of spinal nerves do humans have?
A) 5
B) 12
C) 31
D) It varies, depending on an individual's age and height.
A) 5
B) 12
C) 31
D) It varies, depending on an individual's age and height.
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33
Which cranial nerve carries both motor and sensory information?
A) Facial
B) Olfactory
C) Optic
D) Hypoglossal
A) Facial
B) Olfactory
C) Optic
D) Hypoglossal
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34
The preganglionic neurons of the sympathetic nervous system are found in the
A) basal ganglia.
B) sympathetic chain.
C) spinal cord.
D) muscles.
A) basal ganglia.
B) sympathetic chain.
C) spinal cord.
D) muscles.
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35
Which bodily response is a consequence of sympathetic activation?
A) Increased salivation
B) Increased heart rate
C) Decreased blood pressure
D) Increased digestion
A) Increased salivation
B) Increased heart rate
C) Decreased blood pressure
D) Increased digestion
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36
Refer to the figure.
The plane labeled A is called the _______ plane, the plane labeled B is the _______, and the plane marked C is the _______.
A) dorsal; sagittal; posterior
B) sagittal; ipsilateral; coronal
C) horizontal; sagittal; coronal
D) coronal; horizontal; sagittal

A) dorsal; sagittal; posterior
B) sagittal; ipsilateral; coronal
C) horizontal; sagittal; coronal
D) coronal; horizontal; sagittal
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37
The left and right portions of the body are divided by the _______ plane.
A) sagittal
B) frontal
C) coronal
D) horizontal
A) sagittal
B) frontal
C) coronal
D) horizontal
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38
The four major lobes of the cerebral cortex are named for
A) the skull bones lying over them.
B) their anatomical positions relative to one another.
C) their major functions.
D) their gross appearance.
A) the skull bones lying over them.
B) their anatomical positions relative to one another.
C) their major functions.
D) their gross appearance.
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39
In which plane of section would it be easiest to see the corpus callosum?
A) Sagittal cut directly down the midline
B) Horizontal cut at the level of the brainstem
C) Coronal cut at the level of the cerebellum
D) Sagittal cut at the level of the temporal lobe
A) Sagittal cut directly down the midline
B) Horizontal cut at the level of the brainstem
C) Coronal cut at the level of the cerebellum
D) Sagittal cut at the level of the temporal lobe
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40
What percentage of the surface of the cortex is hidden within the convolutions of the brain?
A) 2%
B) 25%
C) 33%
D) 66%
A) 2%
B) 25%
C) 33%
D) 66%
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41
Which region of the cortex is crucial for motor control?
A) Postcentral gyrus
B) Parietal lobe
C) Precentral gyrus
D) Prefrontal cortex
A) Postcentral gyrus
B) Parietal lobe
C) Precentral gyrus
D) Prefrontal cortex
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42
The ridges of tissue on the convoluted surface of the cortex are called
A) gyri.
B) sulci.
C) nuclei.
D) ganglia.
A) gyri.
B) sulci.
C) nuclei.
D) ganglia.
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43
Almost all incoming sensory information passes through the _______, which sends the information on to the overlying cortex.
A) medulla
B) basal ganglia
C) thalamus
D) cerebellum
A) medulla
B) basal ganglia
C) thalamus
D) cerebellum
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44
The hypothalamus is located _______ to the thalamus.
A) inferior
B) superior
C) dorsal
D) ventral
A) inferior
B) superior
C) dorsal
D) ventral
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45
A collection of neurons in the nervous system is known as a
A) nodule.
B) nucleus.
C) fiber.
D) plexus.
A) nodule.
B) nucleus.
C) fiber.
D) plexus.
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46
The brainstem contains which structure?
A) Medulla
B) Inferior colliculus
C) Corpus callosum
D) Central sulcus
A) Medulla
B) Inferior colliculus
C) Corpus callosum
D) Central sulcus
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47
How many distinct layers are observed in the human neocortex?
A) One
B) Three
C) Six
D) About one-million
A) One
B) Three
C) Six
D) About one-million
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48
Which statement about allocortex is true?
A) It has six cell layers.
B) It is found in the frontal lobe.
C) It can have an unlayered organization.
D) It is organized into columns.
A) It has six cell layers.
B) It is found in the frontal lobe.
C) It can have an unlayered organization.
D) It is organized into columns.
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49
In the cerebral cortex, layers V and VI are unique in that they
A) are a different color than the other layers.
B) contains many neurons with large cell bodies.
C) contains many fibers.
D) are quite variable from region to region.
A) are a different color than the other layers.
B) contains many neurons with large cell bodies.
C) contains many fibers.
D) are quite variable from region to region.
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50
Which structures are part of the basal ganglia?
A) Globus pallidus, caudate nucleus, amygdala
B) Caudate nucleus, putamen, fornix
C) Putamen, amygdala, mammillary bodies
D) Globus pallidus, substantia nigra, putamen
A) Globus pallidus, caudate nucleus, amygdala
B) Caudate nucleus, putamen, fornix
C) Putamen, amygdala, mammillary bodies
D) Globus pallidus, substantia nigra, putamen
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51
Which structure contains the reticular formation?
A) Diencephalon
B) Brainstem
C) Metencephalon
D) Telencephalon
A) Diencephalon
B) Brainstem
C) Metencephalon
D) Telencephalon
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52
Parallel fibers are a feature of the
A) basal ganglia.
B) superior colliculus.
C) corpus callosum.
D) cerebellum.
A) basal ganglia.
B) superior colliculus.
C) corpus callosum.
D) cerebellum.
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53
Two important motor nuclei, the substantia nigra and the _______ nucleus, are contained within the _______.
A) caudate; brainstem
B) oculomotor; diencephalon
C) raphe; telencephalon
D) red; midbrain
A) caudate; brainstem
B) oculomotor; diencephalon
C) raphe; telencephalon
D) red; midbrain
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54
Within the midbrain, the _______ receive auditory (sound) information.
A) inferior colliculi
B) red nucleus
C) superior colliculi
D) reticular formation
A) inferior colliculi
B) red nucleus
C) superior colliculi
D) reticular formation
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55
Purkinje cells are located in the
A) cerebral cortex.
B) cerebellum.
C) cervical spinal cord.
D) basal ganglia.
A) cerebral cortex.
B) cerebellum.
C) cervical spinal cord.
D) basal ganglia.
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56
The ventricular system contains
A) the circle of Willis.
B) blood.
C) cerebrospinal fluid.
D) the meninges.
A) the circle of Willis.
B) blood.
C) cerebrospinal fluid.
D) the meninges.
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57
The specialized vascular tissue that produces the cerebrospinal fluid is called the
A) circle of Willis.
B) dura mater.
C) corpus callosum.
D) choroid plexus.
A) circle of Willis.
B) dura mater.
C) corpus callosum.
D) choroid plexus.
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58
Refer to the figure.
The dashed arrows in this figure represent what key process?
A) The vascular circulation of blood that maintains blood pressure
B) The glymphatic flow that provides protection from harmful substances in the brain
C) The regeneration of the choroid plexus.
D) The opening and closing of the aquaporins to waste material.

A) The vascular circulation of blood that maintains blood pressure
B) The glymphatic flow that provides protection from harmful substances in the brain
C) The regeneration of the choroid plexus.
D) The opening and closing of the aquaporins to waste material.
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59
A person suffers a stroke that affects the base of the anterior cerebral artery. This will likely result in reduced blood flow to the
A) medial frontal and parietal lobes.
B) occipital lobe.
C) lateral temporal lobe.
D) lateral frontal and parietal lobes.
A) medial frontal and parietal lobes.
B) occipital lobe.
C) lateral temporal lobe.
D) lateral frontal and parietal lobes.
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60
Which arteries provide blood to the brain?
A) Basilar artery and carotid artery only
B) Carotid artery and vertebral artery only
C) Basilar artery, carotid artery, and vertebral artery
D) Carotid artery, choroid plexus, and vertebral artery
A) Basilar artery and carotid artery only
B) Carotid artery and vertebral artery only
C) Basilar artery, carotid artery, and vertebral artery
D) Carotid artery, choroid plexus, and vertebral artery
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61
The anterior and middle cerebral arteries branch from the
A) superior vena cava.
B) internal carotid artery.
C) basilar artery.
D) vertebral artery.
A) superior vena cava.
B) internal carotid artery.
C) basilar artery.
D) vertebral artery.
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62
Which statement about the blood-brain barrier is true?
A) It is a part of the immune system that involves the release of antibodies to protect the brain from infectious agents.
B) It is a property of the closely packed endothelial cells of the walls of brain capillaries that prevents large molecules from entering the brain.
C) It is a property of the blood vessels of the brain that promotes the diffusion of nutrients into the tissue of the brain.
D) It is a property of neurons that prevents them from accidentally releasing their neurotransmitters into the blood circulation.
A) It is a part of the immune system that involves the release of antibodies to protect the brain from infectious agents.
B) It is a property of the closely packed endothelial cells of the walls of brain capillaries that prevents large molecules from entering the brain.
C) It is a property of the blood vessels of the brain that promotes the diffusion of nutrients into the tissue of the brain.
D) It is a property of neurons that prevents them from accidentally releasing their neurotransmitters into the blood circulation.
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63
The basilar artery of the brain is formed by the fusion of the _______ arteries.
A) carotid
B) vertebral
C) subclavian
D) femoral
A) carotid
B) vertebral
C) subclavian
D) femoral
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64
_______ makes use of radio waves and magnetic fields to form images of the living brain.
A) CAT
B) MRI
C) PET
D) Angiography
A) CAT
B) MRI
C) PET
D) Angiography
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65
Refer to the photo.
The procedure depicted here is most likely
A) transcranial magnetic stimulation.
B) DTI tractography.
C) dyadic functional MRI.
D) angiography.

A) transcranial magnetic stimulation.
B) DTI tractography.
C) dyadic functional MRI.
D) angiography.
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66
The physiological activity of the brain can be visualized using
A) PET.
B) CT.
C) DTI.
D) electron microscopy.
A) PET.
B) CT.
C) DTI.
D) electron microscopy.
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67
Which imaging technique is not used for studies of the structural details of the brain?
A) CT scan
B) fMRI scan
C) MRI scan
D) Angiography
A) CT scan
B) fMRI scan
C) MRI scan
D) Angiography
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68
Which imaging technology could provide a physician with a very high-resolution image of the thalamus?
A) MRI
B) CT
C) PET
D) DTI
A) MRI
B) CT
C) PET
D) DTI
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69
Which technique does not provide information about the activity level of brain regions?
A) PET
B) fMRI
C) CT
D) Autoradiography
A) PET
B) fMRI
C) CT
D) Autoradiography
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70
Which statement about conventional fMRI is true?
A) Subjects must fast before testing.
B) Subjects must lie completely motionless.
C) It involves the use of X-rays.
D) Subjects must perform specific cognitive tasks.
A) Subjects must fast before testing.
B) Subjects must lie completely motionless.
C) It involves the use of X-rays.
D) Subjects must perform specific cognitive tasks.
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71
A dyadic fMRI could be used to
A) test a person's response to two voices coming through headphones.
B) sequentially examine the brain responses of identical twins.
C) simultaneously examine how two people respond to the same stimulus.
D) stimulate movement of two people simultaneously.
A) test a person's response to two voices coming through headphones.
B) sequentially examine the brain responses of identical twins.
C) simultaneously examine how two people respond to the same stimulus.
D) stimulate movement of two people simultaneously.
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72
What have we learned about the functional organization of the brain from fMRI studies?
A) Local regions of the brain are used for multiple functions across multiple domains, like cognition, language, sensation, emotion, and action planning.
B) Multiple behaviors can be associated with a single specific region in the brain.
C) Multiple cognitive processes can be associated with a single specific region in the brain.
D) During many behaviors and cognitive processes, all the neurons in a local region of the brain will be active at once, as represented by the color scale in an fMRI image.
A) Local regions of the brain are used for multiple functions across multiple domains, like cognition, language, sensation, emotion, and action planning.
B) Multiple behaviors can be associated with a single specific region in the brain.
C) Multiple cognitive processes can be associated with a single specific region in the brain.
D) During many behaviors and cognitive processes, all the neurons in a local region of the brain will be active at once, as represented by the color scale in an fMRI image.
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73
Substances are conveyed from the cell body of the neuron to the distant reaches of the axon through the process of _______.
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74
Although nerve cells typically have only one axon, an axon may divide into numerous axon _______.
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75
The dorsal root consists of _______ projections from the body to the spinal cord.
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76
Almost all incoming sensory information passes through the _______, which sends the information on to the overlying cortex.
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77
The hypothalamus is located _______ to the thalamus.
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78
The _______ sulcus divides the frontal lobe from the parietal lobe.
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79
The most prominent type of neuron of the cerebral cortex-the pyramidal neuron-features an apical dendrite that extends toward the outer surface of the cortex, and _______ dendrites that spread out horizontally from the cell body.
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80
Located within the basal ganglia are the globus pallidus, caudate nucleus, and _______.
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