Deck 34: Alterations of Pulmonary Function in Children

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Question
The most common predisposing factor to obstructive sleep apnea of childhood is adenotonsillar hypertrophy.
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Question
Signs of acute respiratory failure remain the same regardless of etiology.
Question
Children with chronic asthma have clubbing of fingers and toes.
Question
Which of the following shows the correct sequence of events after atelectasis develops in respiratory distress syndrome of the newborn?

A)Increased pulmonary vascular resistance, atelectasis, hypoperfusion
B)Pulmonary hypoperfusion, hypoxic vasoconstriction, right-to-left shunt
C)Respiratory acidosis, hypoxemia, hypercapnia
D)Right-to-left shunt, hypoxic vasoconstriction, hypoperfusion
Question
Paradoxical breathing is an ominous sign in premature infants.
Question
Asthma is one of the leading chronic illnesses in children and has become more prevalent in the past two decades.
Question
Which of the following types of croup is most common?

A)Bacterial
B)Viral
C)Fungal
D)Autoimmune
Question
All alveoli are present and functioning at birth.
Question
Chest wall compliance in infants is __________ in adults.

A)lower than
B)higher than
C)the same as
D)unlike that
Question
Infants up to 3 months of age are obligatory mouth breathers.
Question
Respiratory syncytial virus (RSV) infects nearly 100% of children in the United States by 2 or 3 years of age.
Question
Why is nasal congestion a serious threat to young infants?

A)They are obligatory nose breathers.
B)Their noses are small in diameter.
C)They become dehydrated when mouth breathing.
D)Their epiglottis is proportionally greater than an adult's.
Question
The risk for respiratory distress syndrome (RDS) decreases for premature infants when they are born after _____ weeks of gestation.

A)16
B)20
C)24
D)30
Question
What is the primary cause of RDS of the newborn?

A)An immature immune system
B)Small alveoli
C)A surfactant deficiency
D)Anemia
Question
Surfactant is produced by the fourth week of gestation.
Question
The chief predisposing factor for respiratory distress syndrome (RDS) of the newborn is:

A)low birth weight.
B)alcohol consumption during pregnancy.
C)premature birth.
D)smoking during pregnancy.
Question
Rhinorrhea, sore throat, a low-grade fever, and a seal-like barking cough are clinical manifestations indicative of:

A)epiglottitis.
B)retropharyngeal abscess.
C)bacterial tracheitis.
D)croup.
Question
Which of the following statements about the advances in the treatment of RDS of the newborn is incorrect?

A)Administering glucocorticoids to women in preterm labor accelerates the maturation of the fetus's lungs.
B)Administering oxygen to mothers during preterm labor increases their arterial oxygen before birth of the fetus.
C)Treatment includes the instillation of exogenous surfactant down an endotracheal tube of infants weighing less than 1000 g.
D)Supporting the infant's respiratory function by using continuous positive airway pressure (CPAP). An infant's respiratory function is supported by using continuous pressure (CPAP).
Question
About 75% of aspirated foreign objects in children lodge in a bronchus.
Question
The primary problem in RDS of the newborn is:

A)consolidation.
B)pulmonary edema.
C)atelectasis.
D)bronchiolar plugging.
Question
The release of fibroblast growth factors affects ARDS by causing:

A)atelectasis and decreased lung compliance.
B)disruption of alveolocapillary membrane.
C)pulmonary hypertension.
D)pulmonary fibrosis.
Question
An accurate description of childhood asthma is that it is a(n):

A)obstructive airway disease characterized by reversible airflow obstruction, bronchial hyperreactivity, and inflammation.
B)pulmonary disease characterized by severe hypoxemia, decreased pulmonary compliance, and diffuse densities on chest x-ray.
C)pulmonary disorder involving an abnormal expression of a protein producing viscous mucus that lines the airways, pancreas, sweat ducts, and vas deferens.
D)obstructive airway disease characterized by atelectasis and increased pulmonary resistance as a result of a surfactant deficiency.
Question
Which T lymphocyte phenotype is the key determinant of childhood asthma?

A)CD4 T-helper Th1 lymphocytes
B)CD4 T-helper Th2 lymphocytes
C)CD8 cytotoxic T lymphocytes
D)Memory T lymphocytes
Question
Match the sound of stridor with the location of the problem.
Nasal problems, foreign body, polyps, or choanal atresia

A)Sonorous snoring
B)Muffled voice
C)High-pitched inspiratory sound, voice change, hoarse
D)Expiratory stridor or central wheeze
E)Expiratory wheezes
Question
Which arterial blood gas values would be expected in the acute phase of childhood asthma?

A)pH 7.6, PaCO₂ 35 mmHg, HCO₃ 32 mEq/L
B)pH 7.4, PaCO₂ 40 mmHg, HCO₃ 24 mEq/L
C)pH 7.5, PaCO₂ 30 mmHg, HCO₃ 26 mEq/L
D)pH 7.2, PaCO₂ 20 mmHg, HCO₃ 30 mEq/L
Question
In ARDS, a diffuse pulmonary thrombosis contributes to pulmonary edema by:

A)decreasing the osmotic pressure.
B)increasing the capillary hydrostatic pressure.
C)increasing the pulmonary capillary permeability.
D)decreasing the retention of sodium and water.
Question
Cystic fibrosis is best described as a(n):

A)obstructive airway disease characterized by reversible airflow obstruction, bronchial hyperreactivity, and inflammation.
B)respiratory disease characterized by severe hypoxemia, decreased pulmonary compliance, and diffuse densities on chest x-ray.
C)pulmonary disorder involving an abnormal expression of a protein producing viscous mucus that obstructs the airways, pancreas, sweat ducts, and vas deferens.
D)pulmonary disorder characterized by atelectasis and increased pulmonary resistance as a result of a surfactant deficiency.
Question
Match the sound of stridor with the location of the problem.
Pharyngeal problems

A)Sonorous snoring
B)Muffled voice
C)High-pitched inspiratory sound, voice change, hoarse
D)Expiratory stridor or central wheeze
E)Expiratory wheezes
Question
Bronchiolitis tends to occur during the first years of life and is most often caused by _____ infection.

A)respiratory syncytial virus
B)influenzavirus
C)adenoviruses
D)Epstein-Barr virus
Question
Sudden infant death syndrome (SIDS) occurs most often between _____ and _____ months of age.

A)1; 2
B)3; 4
C)5; 6
D)6; 7
Question
Match the sound of stridor with the location of the problem.
Laryngeal problems

A)Sonorous snoring
B)Muffled voice
C)High-pitched inspiratory sound, voice change, hoarse
D)Expiratory stridor or central wheeze
E)Expiratory wheezes
Question
Match the sound of stridor with the location of the problem.
Bronchial problems

A)Sonorous snoring
B)Muffled voice
C)High-pitched inspiratory sound, voice change, hoarse
D)Expiratory stridor or central wheeze
E)Expiratory wheezes
Question
Match the sound of stridor with the location of the problem.
Tracheal problems

A)Sonorous snoring
B)Muffled voice
C)High-pitched inspiratory sound, voice change, hoarse
D)Expiratory stridor or central wheeze
E)Expiratory wheezes
Question
Acute respiratory distress syndrome (ARDS) is best described as a(n):

A)obstructive airway disease characterized by reversible airflow obstruction, bronchial hyperreactivity, and inflammation.
B)pulmonary disease characterized by severe hypoxemia, decreased pulmonary compliance, and diffuse densities on chest x-ray.
C)respiratory disorder involving an abnormal expression of a protein producing viscous mucus that lines the airways, pancreas, sweat ducts, and vas deferens.
D)pulmonary disorder characterized by atelectasis and increased pulmonary resistance as a result of a surfactant deficiency.
Question
Which immunoglobulin is present in childhood asthma?

A)IgM
B)IgG
C)IgE
D)IgA
Question
Cystic fibrosis (CF) is caused by a(n):

A)autosomal recessive inheritance.
B)autosomal dominant inheritance.
C)infection.
D)malignancy.
Question
Which cytokines activated in childhood asthma produce an allergic response?

A)IL-1, IL-2, and interferon-alpha (IFN-a)
B)IL-8, IL-12, and tumor necrosis factor-alpha (TNF-a)
C)IL-4, IL-10, and colony-stimulating factor (CSF)
D)IL-4, IL-5, and IL-13
Question
What are the clinical manifestations of bacterial pneumonia in children?

A)Mild to high fever, cough, rhinorrhea, crackles, rhonchi, and wheezes
B)High fever, productive cough, and pleuritic chest pain
C)Decreased breath sounds in areas of consolidation and dyspnea
D)Increased respiratory rate and respiratory alkalosis
Question
What are the abnormalities in cytokines found in children with cystic fibrosis?

A)A deficit of IL-1 and an excess of IL-4, IL-12, and IFN-a
B)A deficit of IL-6 and an excess of IL-2, IL-8, and granulocyte colony-stimulating factor (G-CSF)
C)A deficit of IL-10 and an excess of IL-1, IL-8, and TNF-a
D)A deficit of IL-3 and an excess of IL-14, IL-24, and colony-stimulating factor (CSF)
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Deck 34: Alterations of Pulmonary Function in Children
1
The most common predisposing factor to obstructive sleep apnea of childhood is adenotonsillar hypertrophy.
True
2
Signs of acute respiratory failure remain the same regardless of etiology.
True
3
Children with chronic asthma have clubbing of fingers and toes.
False
4
Which of the following shows the correct sequence of events after atelectasis develops in respiratory distress syndrome of the newborn?

A)Increased pulmonary vascular resistance, atelectasis, hypoperfusion
B)Pulmonary hypoperfusion, hypoxic vasoconstriction, right-to-left shunt
C)Respiratory acidosis, hypoxemia, hypercapnia
D)Right-to-left shunt, hypoxic vasoconstriction, hypoperfusion
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k this deck
5
Paradoxical breathing is an ominous sign in premature infants.
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
6
Asthma is one of the leading chronic illnesses in children and has become more prevalent in the past two decades.
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
7
Which of the following types of croup is most common?

A)Bacterial
B)Viral
C)Fungal
D)Autoimmune
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Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
8
All alveoli are present and functioning at birth.
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Unlock Deck
k this deck
9
Chest wall compliance in infants is __________ in adults.

A)lower than
B)higher than
C)the same as
D)unlike that
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Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
10
Infants up to 3 months of age are obligatory mouth breathers.
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k this deck
11
Respiratory syncytial virus (RSV) infects nearly 100% of children in the United States by 2 or 3 years of age.
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
12
Why is nasal congestion a serious threat to young infants?

A)They are obligatory nose breathers.
B)Their noses are small in diameter.
C)They become dehydrated when mouth breathing.
D)Their epiglottis is proportionally greater than an adult's.
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
13
The risk for respiratory distress syndrome (RDS) decreases for premature infants when they are born after _____ weeks of gestation.

A)16
B)20
C)24
D)30
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
14
What is the primary cause of RDS of the newborn?

A)An immature immune system
B)Small alveoli
C)A surfactant deficiency
D)Anemia
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Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
15
Surfactant is produced by the fourth week of gestation.
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k this deck
16
The chief predisposing factor for respiratory distress syndrome (RDS) of the newborn is:

A)low birth weight.
B)alcohol consumption during pregnancy.
C)premature birth.
D)smoking during pregnancy.
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Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
17
Rhinorrhea, sore throat, a low-grade fever, and a seal-like barking cough are clinical manifestations indicative of:

A)epiglottitis.
B)retropharyngeal abscess.
C)bacterial tracheitis.
D)croup.
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
18
Which of the following statements about the advances in the treatment of RDS of the newborn is incorrect?

A)Administering glucocorticoids to women in preterm labor accelerates the maturation of the fetus's lungs.
B)Administering oxygen to mothers during preterm labor increases their arterial oxygen before birth of the fetus.
C)Treatment includes the instillation of exogenous surfactant down an endotracheal tube of infants weighing less than 1000 g.
D)Supporting the infant's respiratory function by using continuous positive airway pressure (CPAP). An infant's respiratory function is supported by using continuous pressure (CPAP).
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Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
19
About 75% of aspirated foreign objects in children lodge in a bronchus.
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Unlock Deck
k this deck
20
The primary problem in RDS of the newborn is:

A)consolidation.
B)pulmonary edema.
C)atelectasis.
D)bronchiolar plugging.
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Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
21
The release of fibroblast growth factors affects ARDS by causing:

A)atelectasis and decreased lung compliance.
B)disruption of alveolocapillary membrane.
C)pulmonary hypertension.
D)pulmonary fibrosis.
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
22
An accurate description of childhood asthma is that it is a(n):

A)obstructive airway disease characterized by reversible airflow obstruction, bronchial hyperreactivity, and inflammation.
B)pulmonary disease characterized by severe hypoxemia, decreased pulmonary compliance, and diffuse densities on chest x-ray.
C)pulmonary disorder involving an abnormal expression of a protein producing viscous mucus that lines the airways, pancreas, sweat ducts, and vas deferens.
D)obstructive airway disease characterized by atelectasis and increased pulmonary resistance as a result of a surfactant deficiency.
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
23
Which T lymphocyte phenotype is the key determinant of childhood asthma?

A)CD4 T-helper Th1 lymphocytes
B)CD4 T-helper Th2 lymphocytes
C)CD8 cytotoxic T lymphocytes
D)Memory T lymphocytes
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
24
Match the sound of stridor with the location of the problem.
Nasal problems, foreign body, polyps, or choanal atresia

A)Sonorous snoring
B)Muffled voice
C)High-pitched inspiratory sound, voice change, hoarse
D)Expiratory stridor or central wheeze
E)Expiratory wheezes
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
25
Which arterial blood gas values would be expected in the acute phase of childhood asthma?

A)pH 7.6, PaCO₂ 35 mmHg, HCO₃ 32 mEq/L
B)pH 7.4, PaCO₂ 40 mmHg, HCO₃ 24 mEq/L
C)pH 7.5, PaCO₂ 30 mmHg, HCO₃ 26 mEq/L
D)pH 7.2, PaCO₂ 20 mmHg, HCO₃ 30 mEq/L
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k this deck
26
In ARDS, a diffuse pulmonary thrombosis contributes to pulmonary edema by:

A)decreasing the osmotic pressure.
B)increasing the capillary hydrostatic pressure.
C)increasing the pulmonary capillary permeability.
D)decreasing the retention of sodium and water.
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
27
Cystic fibrosis is best described as a(n):

A)obstructive airway disease characterized by reversible airflow obstruction, bronchial hyperreactivity, and inflammation.
B)respiratory disease characterized by severe hypoxemia, decreased pulmonary compliance, and diffuse densities on chest x-ray.
C)pulmonary disorder involving an abnormal expression of a protein producing viscous mucus that obstructs the airways, pancreas, sweat ducts, and vas deferens.
D)pulmonary disorder characterized by atelectasis and increased pulmonary resistance as a result of a surfactant deficiency.
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
28
Match the sound of stridor with the location of the problem.
Pharyngeal problems

A)Sonorous snoring
B)Muffled voice
C)High-pitched inspiratory sound, voice change, hoarse
D)Expiratory stridor or central wheeze
E)Expiratory wheezes
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
29
Bronchiolitis tends to occur during the first years of life and is most often caused by _____ infection.

A)respiratory syncytial virus
B)influenzavirus
C)adenoviruses
D)Epstein-Barr virus
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
30
Sudden infant death syndrome (SIDS) occurs most often between _____ and _____ months of age.

A)1; 2
B)3; 4
C)5; 6
D)6; 7
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
31
Match the sound of stridor with the location of the problem.
Laryngeal problems

A)Sonorous snoring
B)Muffled voice
C)High-pitched inspiratory sound, voice change, hoarse
D)Expiratory stridor or central wheeze
E)Expiratory wheezes
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
32
Match the sound of stridor with the location of the problem.
Bronchial problems

A)Sonorous snoring
B)Muffled voice
C)High-pitched inspiratory sound, voice change, hoarse
D)Expiratory stridor or central wheeze
E)Expiratory wheezes
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
33
Match the sound of stridor with the location of the problem.
Tracheal problems

A)Sonorous snoring
B)Muffled voice
C)High-pitched inspiratory sound, voice change, hoarse
D)Expiratory stridor or central wheeze
E)Expiratory wheezes
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
34
Acute respiratory distress syndrome (ARDS) is best described as a(n):

A)obstructive airway disease characterized by reversible airflow obstruction, bronchial hyperreactivity, and inflammation.
B)pulmonary disease characterized by severe hypoxemia, decreased pulmonary compliance, and diffuse densities on chest x-ray.
C)respiratory disorder involving an abnormal expression of a protein producing viscous mucus that lines the airways, pancreas, sweat ducts, and vas deferens.
D)pulmonary disorder characterized by atelectasis and increased pulmonary resistance as a result of a surfactant deficiency.
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
35
Which immunoglobulin is present in childhood asthma?

A)IgM
B)IgG
C)IgE
D)IgA
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
36
Cystic fibrosis (CF) is caused by a(n):

A)autosomal recessive inheritance.
B)autosomal dominant inheritance.
C)infection.
D)malignancy.
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
37
Which cytokines activated in childhood asthma produce an allergic response?

A)IL-1, IL-2, and interferon-alpha (IFN-a)
B)IL-8, IL-12, and tumor necrosis factor-alpha (TNF-a)
C)IL-4, IL-10, and colony-stimulating factor (CSF)
D)IL-4, IL-5, and IL-13
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
38
What are the clinical manifestations of bacterial pneumonia in children?

A)Mild to high fever, cough, rhinorrhea, crackles, rhonchi, and wheezes
B)High fever, productive cough, and pleuritic chest pain
C)Decreased breath sounds in areas of consolidation and dyspnea
D)Increased respiratory rate and respiratory alkalosis
Unlock Deck
Unlock for access to all 39 flashcards in this deck.
Unlock Deck
k this deck
39
What are the abnormalities in cytokines found in children with cystic fibrosis?

A)A deficit of IL-1 and an excess of IL-4, IL-12, and IFN-a
B)A deficit of IL-6 and an excess of IL-2, IL-8, and granulocyte colony-stimulating factor (G-CSF)
C)A deficit of IL-10 and an excess of IL-1, IL-8, and TNF-a
D)A deficit of IL-3 and an excess of IL-14, IL-24, and colony-stimulating factor (CSF)
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Unlock Deck
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