Deck 43: Alterations of Musculoskeletal Function in Children

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Question
In osteomyelitis, infection may spread to adjacent joints in the leg because the epiphyseal plate of the proximal femur is located within the hip joint and the distal femur is partially located within the knee.
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Question
The normal lordotic curve of the lower spine begins to develop when the infant begins sitting.
Question
The total mass of muscle in the body can be estimated from which serum laboratory test value?

A)Albumin
B)Blood urea nitrogen
C)Creatinine
D)Creatine
Question
An insufficient dietary intake of vitamin _____ can lead to rickets in children.

A)C
B)B12
C)B6
D)D
Question
Bone growth takes place at the same rate at both ends of the bones because they are under hormonal control.
Question
Which disorder is characterized by failure of bones to ossify resulting in soft bones and skeletal deformity?

A)Osteogenesis imperfecta
B)Rickets
C)Osteochondrosis
D)Legg-Calvé-Perthes disease
Question
What diagnosis is given when the infant's hip maintains contact with the acetabulum, but is not well seated within the hip joint?

A)Dislocatable hip
B)Subluxated hip
C)Dislocated hip
D)Subluxable hip
Question
The most common skeletal defect of the upper extremity is:

A)vestigial tabs.
B)Paget disease.
C)rickets.
D)syndactyly.
Question
Staphylococcus aureus may cause osteomyelitis in newborns and older children.
Question
Which serum laboratory test is elevated in all forms of osteogenesis imperfecta?

A)Phosphorus
B)Calcium
C)Alkaline phosphatase
D)Total protein
Question
Which skeletal deformity is normal at birth, but disappears by age 2 1/2 years?

A)Genu varum (bowleg)
B)Genu valgum (knock knee)
C)Equinovarus (clubfoot)
D)Pes planus (flat feet)
Question
Limb girdle muscular dystrophy is a possible diagnosis when acute causes of proximal weakness are eliminated as well as Duchenne and facioscapulohumeral muscular dystrophies.
Question
Which of the following is a very late sign or symptom of developmental dysplasia of the hip (DDH)?

A)Asymmetry of the gluteal or thigh folds
B)Leg length discrepancy
C)Waddling gait
D)Pain
Question
The appendicular skeleton grows faster than the axial skeleton during childhood.
Question
Poor posture results in structural scoliosis.
Question
Unlike adult-onset RA, JRA is not a syndrome that is often accompanied by systemic manifestations.
Question
In scoliosis, curves in the thoracic spine greater than _____ degrees result in decreased pulmonary function.

A)40
B)50
C)60
D)80
Question
The _____ is cartilage that retains the ability to form and calcify new cartilage and deposit bone until the skeleton matures.

A)epiphyseal line
B)physeal plate
C)epiphyseal cartilage
D)metaphyseal plate
Question
In osteomyelitis, bacteria gain access to the subperiosteal space in the metaphysis, which is considered the "path of least resistance." What factor makes this route for bacteria the path of least resistance?

A)Cortex of the bone in this area is porous or maze-like.
B)Blood supply to the metaphysis is easily compromised.
C)Macrophages and lymphocytes have limited access to the subperiosteal space.
D)Bacteria usually spread down the medullary cavity of the bone.
Question
In adult rheumatoid arthritis (AR) and juvenile rheumatoid arthritis (JRA), the large joints are predominantly affected.
Question
Facioscapulohumeral muscular dystrophy is likely inherited from one's:

A)father.
B)mother.
C)affected parent.
D)maternal lineage.
Question
Match the type of muscular dystrophy with its description. The types may be used more than once.
Often called benign Duchenne muscular dystrophy because it shares the inheritance link, but produces milder symptoms

A)Duchenne muscular dystrophy
B)Facioscapulohumeral muscular dystrophy
C)Scapuloperoneal muscular dystrophy
D)Myotonic dystrophy
E)Becker muscular dystrophy
Question
Rhabdomyosarcoma can develop anywhere _____ muscle is located.

A)cardiac
B)smooth
C)involuntary
D)striated
Question
Molecular analysis has demonstrated that osteosarcoma is associated with:

A)TP53.
B)src.
C)myc.
D)TSC2.
Question
Ewing sarcoma arises from:

A)bone marrow.
B)bone-producing mesenchymal cells.
C)metadiaphysis of long bones.
D)embryonal osteocytes.
Question
Match the type of muscular dystrophy with its description. The types may be used more than once.
The face is expressionless and pouting of the lips makes whistling impossible.

A)Duchenne muscular dystrophy
B)Facioscapulohumeral muscular dystrophy
C)Scapuloperoneal muscular dystrophy
D)Myotonic dystrophy
E)Becker muscular dystrophy
Question
Osgood-Schlatter disease is characterized by:

A)lateral epicondylitis of the elbow.
B)inflammation of the anterior cruciate ligament.
C)bursitis of the subscapular bursa in the glenohumeral joint.
D)tendinitis of the anterior patellar tendon.
Question
Which bones are affected in Legg-Calvé-Perthes disease?

A)Heads of the femur
B)Distal femurs
C)Heads of the humerus
D)Distal tibias
Question
Osteochondrosis is caused by a(n):

A)imbalance between calcitonin and parathyroid hormone.
B)nutritional deficiency of calcium and phosphorus.
C)bacterial infection of the bone.
D)vascular impairment and trauma to bone.
Question
Osteosarcomas usually metastasize to the:

A)pancreas.
B)liver.
C)lungs.
D)brain.
Question
Which protein, absent in muscle cells of Duchenne muscular dystrophy, mediates the anchoring of skeletal muscles fibers to the basement membrane?

A)Syntrophin
B)Laminin
C)Dystrophin
D)Troponin
Question
Match the type of muscular dystrophy with its description. The types may be used more than once.
Distal muscles of the lower extremities are involved causing footdrop.

A)Duchenne muscular dystrophy
B)Facioscapulohumeral muscular dystrophy
C)Scapuloperoneal muscular dystrophy
D)Myotonic dystrophy
E)Becker muscular dystrophy
Question
Pulmonary complications in children with Duchenne muscular dystrophy are contributed to:

A)chronic heart failure.
B)kyphoscoliosis.
C)impaired formation of alveoli.
D)anemia.
Question
Which of the following muscular dystrophy syndromes develops from an X-linked recessive mode of inheritance?

A)Duchenne
B)Facioscapulohumeral
C)Myotonic
D)Limb girdle
Question
Match the type of muscular dystrophy with its description. The types may be used more than once.
Onset at approximately age 3 with rapid progression and frequent mental retardation

A)Duchenne muscular dystrophy
B)Facioscapulohumeral muscular dystrophy
C)Scapuloperoneal muscular dystrophy
D)Myotonic dystrophy
E)Becker muscular dystrophy
Question
How are the clinical manifestations and onset of JRA different from RA in adults?

A)JRA begins insidiously with systemic signs of inflammation.
B)JRA predominantly affects large joints.
C)JRA has more severe joint pain than RA.
D)JRA has a rapid onset of generalized aches as the first symptom.
Question
The most common malignant bone tumor during childhood is:

A)chondrosarcoma.
B)fibrosarcoma.
C)Ewing sarcoma.
D)osteosarcoma.
Question
Match the type of muscular dystrophy with its description. The types may be used more than once.
Autosomal dominant with a slow rate of progression and frequent mental retardation.

A)Duchenne muscular dystrophy
B)Facioscapulohumeral muscular dystrophy
C)Scapuloperoneal muscular dystrophy
D)Myotonic dystrophy
E)Becker muscular dystrophy
Question
The pain experienced in Legg-Calvé-Perthes disease is referred to as involving:

A)elbows and upper and lower arms that is aggravated by activity and relieved by rest.
B)knees, inner thighs, and groin and is described as a continuous ache and relieved by anti-inflammatory drugs.
C)knees, inner thighs, and groin that is aggravated by activity and relieved by rest.
D)elbows and upper and lower arms and is described as a continuous ache and relieved by anti-inflammatory drugs.
Question
Cerebral palsy is usually a result of:

A)brain ischemia during birth.
B)prematurity.
C)congenital defects.
D)genetic defect.
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Deck 43: Alterations of Musculoskeletal Function in Children
1
In osteomyelitis, infection may spread to adjacent joints in the leg because the epiphyseal plate of the proximal femur is located within the hip joint and the distal femur is partially located within the knee.
True
2
The normal lordotic curve of the lower spine begins to develop when the infant begins sitting.
True
3
The total mass of muscle in the body can be estimated from which serum laboratory test value?

A)Albumin
B)Blood urea nitrogen
C)Creatinine
D)Creatine
Creatinine
4
An insufficient dietary intake of vitamin _____ can lead to rickets in children.

A)C
B)B12
C)B6
D)D
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
5
Bone growth takes place at the same rate at both ends of the bones because they are under hormonal control.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
6
Which disorder is characterized by failure of bones to ossify resulting in soft bones and skeletal deformity?

A)Osteogenesis imperfecta
B)Rickets
C)Osteochondrosis
D)Legg-Calvé-Perthes disease
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
7
What diagnosis is given when the infant's hip maintains contact with the acetabulum, but is not well seated within the hip joint?

A)Dislocatable hip
B)Subluxated hip
C)Dislocated hip
D)Subluxable hip
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
8
The most common skeletal defect of the upper extremity is:

A)vestigial tabs.
B)Paget disease.
C)rickets.
D)syndactyly.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
9
Staphylococcus aureus may cause osteomyelitis in newborns and older children.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
10
Which serum laboratory test is elevated in all forms of osteogenesis imperfecta?

A)Phosphorus
B)Calcium
C)Alkaline phosphatase
D)Total protein
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
11
Which skeletal deformity is normal at birth, but disappears by age 2 1/2 years?

A)Genu varum (bowleg)
B)Genu valgum (knock knee)
C)Equinovarus (clubfoot)
D)Pes planus (flat feet)
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
12
Limb girdle muscular dystrophy is a possible diagnosis when acute causes of proximal weakness are eliminated as well as Duchenne and facioscapulohumeral muscular dystrophies.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
13
Which of the following is a very late sign or symptom of developmental dysplasia of the hip (DDH)?

A)Asymmetry of the gluteal or thigh folds
B)Leg length discrepancy
C)Waddling gait
D)Pain
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
14
The appendicular skeleton grows faster than the axial skeleton during childhood.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
15
Poor posture results in structural scoliosis.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
16
Unlike adult-onset RA, JRA is not a syndrome that is often accompanied by systemic manifestations.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
17
In scoliosis, curves in the thoracic spine greater than _____ degrees result in decreased pulmonary function.

A)40
B)50
C)60
D)80
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
18
The _____ is cartilage that retains the ability to form and calcify new cartilage and deposit bone until the skeleton matures.

A)epiphyseal line
B)physeal plate
C)epiphyseal cartilage
D)metaphyseal plate
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
19
In osteomyelitis, bacteria gain access to the subperiosteal space in the metaphysis, which is considered the "path of least resistance." What factor makes this route for bacteria the path of least resistance?

A)Cortex of the bone in this area is porous or maze-like.
B)Blood supply to the metaphysis is easily compromised.
C)Macrophages and lymphocytes have limited access to the subperiosteal space.
D)Bacteria usually spread down the medullary cavity of the bone.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
20
In adult rheumatoid arthritis (AR) and juvenile rheumatoid arthritis (JRA), the large joints are predominantly affected.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
21
Facioscapulohumeral muscular dystrophy is likely inherited from one's:

A)father.
B)mother.
C)affected parent.
D)maternal lineage.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
22
Match the type of muscular dystrophy with its description. The types may be used more than once.
Often called benign Duchenne muscular dystrophy because it shares the inheritance link, but produces milder symptoms

A)Duchenne muscular dystrophy
B)Facioscapulohumeral muscular dystrophy
C)Scapuloperoneal muscular dystrophy
D)Myotonic dystrophy
E)Becker muscular dystrophy
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
23
Rhabdomyosarcoma can develop anywhere _____ muscle is located.

A)cardiac
B)smooth
C)involuntary
D)striated
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
24
Molecular analysis has demonstrated that osteosarcoma is associated with:

A)TP53.
B)src.
C)myc.
D)TSC2.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
25
Ewing sarcoma arises from:

A)bone marrow.
B)bone-producing mesenchymal cells.
C)metadiaphysis of long bones.
D)embryonal osteocytes.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
26
Match the type of muscular dystrophy with its description. The types may be used more than once.
The face is expressionless and pouting of the lips makes whistling impossible.

A)Duchenne muscular dystrophy
B)Facioscapulohumeral muscular dystrophy
C)Scapuloperoneal muscular dystrophy
D)Myotonic dystrophy
E)Becker muscular dystrophy
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
27
Osgood-Schlatter disease is characterized by:

A)lateral epicondylitis of the elbow.
B)inflammation of the anterior cruciate ligament.
C)bursitis of the subscapular bursa in the glenohumeral joint.
D)tendinitis of the anterior patellar tendon.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
28
Which bones are affected in Legg-Calvé-Perthes disease?

A)Heads of the femur
B)Distal femurs
C)Heads of the humerus
D)Distal tibias
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
29
Osteochondrosis is caused by a(n):

A)imbalance between calcitonin and parathyroid hormone.
B)nutritional deficiency of calcium and phosphorus.
C)bacterial infection of the bone.
D)vascular impairment and trauma to bone.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
30
Osteosarcomas usually metastasize to the:

A)pancreas.
B)liver.
C)lungs.
D)brain.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
31
Which protein, absent in muscle cells of Duchenne muscular dystrophy, mediates the anchoring of skeletal muscles fibers to the basement membrane?

A)Syntrophin
B)Laminin
C)Dystrophin
D)Troponin
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
32
Match the type of muscular dystrophy with its description. The types may be used more than once.
Distal muscles of the lower extremities are involved causing footdrop.

A)Duchenne muscular dystrophy
B)Facioscapulohumeral muscular dystrophy
C)Scapuloperoneal muscular dystrophy
D)Myotonic dystrophy
E)Becker muscular dystrophy
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
33
Pulmonary complications in children with Duchenne muscular dystrophy are contributed to:

A)chronic heart failure.
B)kyphoscoliosis.
C)impaired formation of alveoli.
D)anemia.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
34
Which of the following muscular dystrophy syndromes develops from an X-linked recessive mode of inheritance?

A)Duchenne
B)Facioscapulohumeral
C)Myotonic
D)Limb girdle
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
35
Match the type of muscular dystrophy with its description. The types may be used more than once.
Onset at approximately age 3 with rapid progression and frequent mental retardation

A)Duchenne muscular dystrophy
B)Facioscapulohumeral muscular dystrophy
C)Scapuloperoneal muscular dystrophy
D)Myotonic dystrophy
E)Becker muscular dystrophy
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
36
How are the clinical manifestations and onset of JRA different from RA in adults?

A)JRA begins insidiously with systemic signs of inflammation.
B)JRA predominantly affects large joints.
C)JRA has more severe joint pain than RA.
D)JRA has a rapid onset of generalized aches as the first symptom.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
37
The most common malignant bone tumor during childhood is:

A)chondrosarcoma.
B)fibrosarcoma.
C)Ewing sarcoma.
D)osteosarcoma.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
38
Match the type of muscular dystrophy with its description. The types may be used more than once.
Autosomal dominant with a slow rate of progression and frequent mental retardation.

A)Duchenne muscular dystrophy
B)Facioscapulohumeral muscular dystrophy
C)Scapuloperoneal muscular dystrophy
D)Myotonic dystrophy
E)Becker muscular dystrophy
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
39
The pain experienced in Legg-Calvé-Perthes disease is referred to as involving:

A)elbows and upper and lower arms that is aggravated by activity and relieved by rest.
B)knees, inner thighs, and groin and is described as a continuous ache and relieved by anti-inflammatory drugs.
C)knees, inner thighs, and groin that is aggravated by activity and relieved by rest.
D)elbows and upper and lower arms and is described as a continuous ache and relieved by anti-inflammatory drugs.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
40
Cerebral palsy is usually a result of:

A)brain ischemia during birth.
B)prematurity.
C)congenital defects.
D)genetic defect.
Unlock Deck
Unlock for access to all 40 flashcards in this deck.
Unlock Deck
k this deck
locked card icon
Unlock Deck
Unlock for access to all 40 flashcards in this deck.