Deck 26: Hypersensitivity Reactions

Question 1

Immune complex reactions can:

A) suppress or augment the immune response.
B) inhibit tumor cell destruction.
C) be deposited in blood vessel walls,glomerular membranes,and other sites.
D) all of the above.

Answer 1

all of the above.

Question 2

MATCHING
Match the terms with the appropriate description.

Anaphylactoid reaction

A)Cell-mediated
B)Antibody-mediated
C)Dependent on the host's response to a subsequent exposure of antigen
D)Not mediated by antigen-antibody interaction

Answer 2

Not mediated by antigen-antibody interaction

Question 3

MATCHING
Match the terms with the appropriate description.

Immediate hypersensitivity

A)Cell-mediated
B)Antibody-mediated
C)Dependent on the host's response to a subsequent exposure of antigen
D)Not mediated by antigen-antibody interaction

Answer 3

Antibody-mediated

Question 4

Asthma is an example of a _____________ hypersensitivity reaction.

A) type I
B) type II
C) type III
D) type IV

Question 5

Fill in the blanks in the table.
Classification of Hypersensitivity Reactions

Options for 1-4:
A)Anaphylactic
B)T cell-dependent
C)Cytotoxic
D)Immune complex
Options for 5 and 6:
A)IgM
B)IgG
C)IgE
D)None
Options for 7:
A)Yes
B)No
Options for 8-11:

A)Anaphylaxis,hay fever,asthma,food allergy
B)Thrombocytopenia,transfusion reactions,hemolytic disease of newborn
C)Allergy or infection,contact dermatitis
D)Arthus reaction,serum sickness

Question 6

Anaphylaxis is characterized by all the following statements except:

A) it can cause death caused by asphyxiation.
B) there is massive release of histamine from mast cells and basophils.
C) there was prior sensitization to an allergen.
D) it is associated with a significant increase in eosinophils in the circulating blood.

Question 7

Table 26-1
Classification of Hypersensitivity Reactions

Hemolytic disease of the newborn is an example of a ____________ hypersensitivity reaction.

A) type I
B) type II
C) type III
D) type IV

Question 8

Cell-mediated immunity is responsible for:

A) contact sensitivity.
B) elimination of tumor cells bearing neoantigens.
C) rejection of foreign graft tissue.
D) all of the above.

Question 9

The Arthus reaction is associated with the immune phenomenon of:

A) deposition of immune complexes in blood vessels.
B) release of histamine from tissue basophils.
C) destruction of body tissue by cytotoxic T lymphocytes.
D) phagocytosis of IgG-coated erythrocytes.

Question 10

MATCHING
Match the terms with the appropriate description.

Immunization,or sensitization

A)Cell-mediated
B)Antibody-mediated
C)Dependent on the host's response to a subsequent exposure of antigen
D)Not mediated by antigen-antibody interaction

Question 11

Histamine can:

A) lead to constriction of bronchial smooth muscle.
B) exert an anticoagulant effect.
C) cause decreased capillary permeability.
D) enhance opsonization in phagocytosis.

Question 12

Type I hypersensitivity reactions are characterized by:

A) activation of complement.
B) antigen cross-links with IgE on mast cells.
C) being potentially fatal.
D) both b and c

Question 13

The components involved in a positive skin test for tuberculosis (TB)are:

A) T lymphocytes and macrophages.
B) segmented neutrophils and monocytes.
C) B lymphocytes and macrophages.
D) IgE antibodies.

Question 14

Fill in the blanks in the table with the appropriate primary actions.

A)Increases vascular permeability.
B)Contracts smooth muscle.
C)Alters bronchial smooth muscle and enhances the effects of histamine on target organs.

Question 15

MATCHING
Match the terms with the appropriate description.

Delayed hypersensitivity

A)Cell-mediated
B)Antibody-mediated
C)Dependent on the host's response to a subsequent exposure of antigen
D)Not mediated by antigen-antibody interaction