Question 1

MATCHING
Match the terms with the appropriate description.

-Delayed hypersensitivity

Accepted Answer

A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction 
A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction A

Question 2

Fill in the blanks in the table with the appropriate primary actions.
 
A)Increases vascular permeability.
B)Contracts smooth muscle.
C)Alters bronchial smooth muscle and enhances the effects of histamine on target organs.

Accepted Answer

1,A;2,C;3,B

Question 3

The components involved in a positive skin test for tuberculosis (TB)are:

Accepted Answer

A)  T lymphocytes and macrophages. 
B)  segmented neutrophils and monocytes. 
C)  B lymphocytes and macrophages. 
D)  IgE antibodies. 
A)  T lymphocytes and macrophages. 
B)  segmented neutrophils and monocytes. 
C)  B lymphocytes and macrophages. 
D)  IgE antibodies. A

Question 4

MATCHING
Match the terms with the appropriate description.

-Immunization,or sensitization

Accepted Answer

A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction 
A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction

Question 5

The Arthus reaction is associated with the immune phenomenon of:

Accepted Answer

A)  deposition of immune complexes in blood vessels. 
B)  release of histamine from tissue basophils. 
C)  destruction of body tissue by cytotoxic T lymphocytes. 
D)  phagocytosis of IgG-coated erythrocytes. 
A)  deposition of immune complexes in blood vessels. 
B)  release of histamine from tissue basophils. 
C)  destruction of body tissue by cytotoxic T lymphocytes. 
D)  phagocytosis of IgG-coated erythrocytes.

Question 6

MATCHING
Match the terms with the appropriate description.

-Immediate hypersensitivity

Accepted Answer

A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction 
A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction

Question 7

Table 26-1
Classification of Hypersensitivity Reactions
 
Hemolytic disease of the newborn is an example of a ____________ hypersensitivity reaction.

Accepted Answer

A)  type I 
B)  type II 
C)  type III 
D)  type IV 
A)  type I 
B)  type II 
C)  type III 
D)  type IV

Question 8

Type I hypersensitivity reactions are characterized by:

Accepted Answer

A)  activation of complement. 
B)  antigen cross-links with IgE on mast cells. 
C)  being potentially fatal. 
D)  both b and c 
A)  activation of complement. 
B)  antigen cross-links with IgE on mast cells. 
C)  being potentially fatal. 
D)  both b and c

Question 9

Histamine can:

Accepted Answer

A)  lead to constriction of bronchial smooth muscle. 
B)  exert an anticoagulant effect. 
C)  cause decreased capillary permeability. 
D)  enhance opsonization in phagocytosis. 
A)  lead to constriction of bronchial smooth muscle. 
B)  exert an anticoagulant effect. 
C)  cause decreased capillary permeability. 
D)  enhance opsonization in phagocytosis.

Question 10

Fill in the blanks in the table.
Classification of Hypersensitivity Reactions
  
Options for 1-4:
A)Anaphylactic
B)T cell-dependent
C)Cytotoxic
D)Immune complex
Options for 5 and 6:
A)IgM
B)IgG
C)IgE
D)None
Options for 7:
A)Yes
B)No
Options for 8-11:
A)Anaphylaxis,hay fever,asthma,food allergy
B)Thrombocytopenia,transfusion reactions,hemolytic disease of newborn
C)Allergy or infection,contact dermatitis
D)Arthus reaction,serum sickness

Accepted Answer

1,A;2,C;3,D;4,B;5,B;

Question 11

Cell-mediated immunity is responsible for:

Accepted Answer

A)  contact sensitivity. 
B)  elimination of tumor cells bearing neoantigens. 
C)  rejection of foreign graft tissue. 
D)  all of the above. 
A)  contact sensitivity. 
B)  elimination of tumor cells bearing neoantigens. 
C)  rejection of foreign graft tissue. 
D)  all of the above.

Question 12

MATCHING
Match the terms with the appropriate description.

-Anaphylactoid reaction

Accepted Answer

A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction 
A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction

Question 13

Anaphylaxis is characterized by all the following statements except:

Accepted Answer

A)  it can cause death caused by asphyxiation. 
B)  there is massive release of histamine from mast cells and basophils. 
C)  there was prior sensitization to an allergen. 
D)  it is associated with a significant increase in eosinophils in the circulating blood. 
A)  it can cause death caused by asphyxiation. 
B)  there is massive release of histamine from mast cells and basophils. 
C)  there was prior sensitization to an allergen. 
D)  it is associated with a significant increase in eosinophils in the circulating blood.

Question 14

Asthma is an example of a _____________ hypersensitivity reaction.

Accepted Answer

A)  type I 
B)  type II 
C)  type III 
D)  type IV 
A)  type I 
B)  type II 
C)  type III 
D)  type IV

Question 15

Immune complex reactions can:

Accepted Answer

A)  suppress or augment the immune response. 
B)  inhibit tumor cell destruction. 
C)  be deposited in blood vessel walls,glomerular membranes,and other sites. 
D)  all of the above. 
A)  suppress or augment the immune response. 
B)  inhibit tumor cell destruction. 
C)  be deposited in blood vessel walls,glomerular membranes,and other sites. 
D)  all of the above.

Exam 26: Hypersensitivity Reactions

MATCHING Match the terms with the appropriate description. -Delayed hypersensitivity

Fill in the blanks in the table with the appropriate primary actions. A)Increases vascular permeability. B)Contracts smooth muscle. C)Alters bronchial smooth muscle and enhances the effects of histamine on target organs.

The components involved in a positive skin test for tuberculosis (TB)are:

MATCHING Match the terms with the appropriate description. -Immunization,or sensitization

The Arthus reaction is associated with the immune phenomenon of:

MATCHING Match the terms with the appropriate description. -Immediate hypersensitivity

Table 26-1 Classification of Hypersensitivity Reactions Hemolytic disease of the newborn is an example of a ____________ hypersensitivity reaction.

Type I hypersensitivity reactions are characterized by:

Histamine can:

Cell-mediated immunity is responsible for:

MATCHING Match the terms with the appropriate description. -Anaphylactoid reaction

Anaphylaxis is characterized by all the following statements except:

Asthma is an example of a _____________ hypersensitivity reaction.

Immune complex reactions can:

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Point-Of-Care Testing

Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Automated Procedures

Molecular Techniques

The Immune Response in Infectious Diseases

A Primer on Vaccines

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Toxoplasmosis

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Acquired Immunodeficiency Syndrome

Immunoproliferative Disorders

Autoimmune Disorders

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Solid Organ Transplantation

Bone Marrow Transplantation

Tumor Immunology

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