Deck 12: Muscle: Mechanisms of Contraction and Neural Control

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Question
The biceps brachii causes flexion of the elbow.The triceps brachii causes extension of the elbow,so it would be a/an

A)abductor.
B)antagonist.
C)agonist.
D)levator.
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Question
Skeletal muscles with a low innervation ratio have a low degree of neural control.
Question
The light band of a skeletal muscle is known as the

A)A band.
B)Z disc.
C)I band.
D)H banD.
Question
The specialized region of the sarcolemma at the neuromuscular junction is called the

A)syncytium.
B)varicosity.
C)fascicle.
D)motor end plate.
Question
Skeletal muscle cells are multinucleated.This is called a/an

A)myoblast.
B)striation.
C)syncytium.
D)endomysium.
Question
The origin is the point of muscle attachment that is most stationary.
Question
The more movable bony attachment is the

A)flexor.
B)origin.
C)extensor.
D)insertion.
Question
Duchenne's muscular dystrophy

A)is an X-linked recessive trait.
B)most often affects women.
C)involves degeneration of the smooth muscle dense bodies.
D)All apply.
Question
Longer,stronger muscles have motor units with very few fibers.
Question
The prime mover of any skeletal movement is called the

A)flexor.
B)agonist.
C)abductor.
D)antagonist.
Question
The deadly botulinum toxin can be used in the cosmetic treatment of skin wrinkles because it produces a flaccid paralysis.
Question
Flexors increase the angle at a joint.
Question
Motor unit recruitment allows for _________ contraction strength.

A)increased
B)decreased
C)no change in
Question
The epimysium surrounds the individual muscle cells.
Question
A muscle that constricts an opening is a/an

A)extensor.
B)levator.
C)antagonist.
D)sphincter.
Question
Z discs are found bisecting the A bands.
Question
Each fascicle of a muscle is surrounded by the

A)perimysium.
B)epimysium.
C)endomysium.
D)sarcolemma.
Question
Muscles which move a limb away the midline of the body are termed as

A)abductor muscles.
B)adductor muscles.
C)extensor muscles.
D)flexor muscles.
Question
When skeletal muscle cells contract,they increase in length.
Question
Which of the following is needed for the myosin head to undergo a power stroke?

A)release of Pi
B)binding of ATP to the head
C)splitting of ATP into ADP and Pi
D)addition of Ca2+ to the head
Question
During skeletal muscle contraction,adjacent _________ are pulled closer together as the _______ between them shorten.

A)A bands;I bands
B)I bands;A bands
C)Z disks;A bands
D)Z disks;M lines
Question
Thin filaments are composed of myosin and tropomyosin.
Question
What protein primarily makes up the thin filament?

A)actin
B)myosin
C)titin
D)Z-discs
Question
Subunits of skeletal muscle cells that are composed of sarcomeres are called

A)myofibrils.
B)myofilaments.
C)sarcolemmas.
D)transverse tubules.
Question
During skeletal muscle contraction the A band decreases in size.
Question
What structure is composed of protein filaments and is located in the center of the thick filaments?

A)Z disk
B)titin
C)M line
D)actin
Question
What enzyme is needed to start the cross bridging process?

A)creatine phosphatase
B)kinase
C)myosin ATPase
D)Ca2+ATPase
Question
What muscle structural and functional unit runs from Z disc to Z disc?

A)A band
B)I band
C)sarcomere
D)myofibril
Question
What protein primarily makes up the thick filament?

A)actin
B)myosin
C)titin
D)troponin
Question
Myosin contains binding sites for ______________ and _____________.

A)sodium,calcium.
B)troponin,ATP.
C)ATP,actin.
D)actin,calcium.
Question
Myosin will not bind to actin unless ADP is bound to the myosin head.
Question
Cross-bridge formation occurs when myosin heads attach to actin molecules located in the thin filaments.
Question
The thick filament is also called the

A)A band.
B)I band.
C)H band.
D)M line.
Question
What is the lighter area in the center of the A-band called?

A)M-line
B)titin
C)Z-disc
D)H band
Question
Each somatic motor neuron with all the muscle fibers it innervates is a

A)fascicle.
B)varicosity.
C)motor unit.
D)sarcolemma.
Question
What structure runs the length of the sarcomere and contributes to the elastic recoil in muscle?

A)Z disk
B)titin
C)M line
D)actin
Question
Sarcomeres contain elastic titin filaments which help the muscles return to their resting length during muscle relaxation.
Question
Somatic motor neurons release the neurotransmitter _________ at the neuromuscular junction.

A)dopamine
B)acetylcholine
C)norepinephrine
D)serotonin
Question
The thick filament is split by a Z disc.
Question
The pumps that actively transport calcium back into the _______ are called Ca2+ -ATPase pumps.

A)transverse tubules
B)sarcoplasmic reticulum
C)neuromuscular junction
D)None apply.
Question
What is the role of ATP in muscle contraction and relaxation?

A)It is hydrolyzed from the myosin head to attach to actin.
B)It causes myosin head to detach from actin.
C)It powers the Ca2+ pumps to return Ca2+ to the SR.
D)All apply.
Question
The actin filament is a polymer formed from 300 to 400 globular subunits called

A)I-actin.
B)T-actin.
C)G-actin.
D)C-actin.
Question
The process by which action potentials cause muscle contraction is

A)the sliding filament theory.
B)excitation-contraction coupling.
C)the electromechanical release mechanism.
D)Both excitation-contraction coupling and the electromechanical release mechanism.
Question
During skeletal muscle contraction,

A)the H band increases in size.
B)Ca2+ associates with tropomyosin.
C)myosin heads interact with tropomyosin.
D)thin filaments slide across thick filaments.
Question
The _________ complex contains three proteins designated as the I,T,and C types.

A)actin
B)myosin
C)tropomyosin
D)troponin
Question
The inability of muscle cells to relax due to high frequency stimulation is termed

A)treppe.
B)recruitment.
C)twitch.
D)tetanus.
Question
Which of the following molecules is NOT part of the thin filament?

A)actin
B)titin
C)troponin
D)tropomyosin
Question
What structures carry the action potentials into the interior of the muscle to cause muscle contraction?

A)T tubules
B)terminal cisternae
C)sarcoplasmic reticula
D)ryanodine receptors
Question
When a muscle is stimulated to contract,calcium release channels in the SR will release Ca2+ by

A)active transport.
B)facilitated diffusion.
C)passive diffusion.
D)exocytosis.
Question
Which molecule blocks the myosin head from binding to actin in a relaxed muscle?

A)tropomyosin
B)troponin
C)calcium
D)titin
Question
Which of the following is NOT true of the relaxation of a muscle fiber?

A)ATP is needed to fuel the calcium pumps
B)calcium release channels close
C)the action potential must continue
D)Ca2+ moves from the sarcoplasm to the sarcoplasmic reticula
Question
Ca2+ must bind to tropomyosin so that the myosin binding sites on actin will be accessible to the myosin.
Question
The Ca2+ required for skeletal muscle contraction

A)is released from the sarcoplasmic reticulum.
B)enters the cell due to the opening of voltage regulated Ca2+ channels from the T tubules.
C)is actively transported into the cell.
D)is released from mitochondria.
Question
Which of the following does NOT occur during the cross bridge cycle?

A)a second ATP binding causes cross bridges to release.
B)ADP is released at the end of the power stroke.
C)energized myosin heads bind troponin.
D)ATP hydrolysis allows for cross bridge formation.
Question
Transverse tubules contain voltage-gated calcium channels that respond to membrane depolarization and are directly coupled to the calcium release channels in the sarcoplasmic reticulum.
Question
________ is characterized by continued attachment of myosin heads to actin filaments due to a lack of ATP.

A)Tetanus
B)Rigor mortis
C)Flaccid paralysis
D)Treppe
Question
Increasing the frequency of action potentials in a somatic motor neuron will induce increased force of muscle contraction.
Question
The movement of the troponin-tropomyosin complex requires

A)ATP.
B)Ca2+.
C)acetylcholine.
D)Na+.
Question
Summation occurs in muscle cells when stimulus frequency increases to produce a greater force contraction.
Question
A shortening of the muscle that occurs when the tension is greater than the load is a(n)

A)concentric contraction.
B)isometric contraction.
C)eccentric contraction.
D)isokinetic contraction.
Question
Isotonic muscle contractions are often preceded by isometric contractions.
Question
ATP in muscle contraction is needed for

A)attachment of myosin cross bridges to actin.
B)release of myosin cross bridges from actin.
C)pumping of Ca2+ back into the sarcoplasmic reticulum.
D)All apply.
Question
High-energy phosphates are stored in skeletal muscle as creatine phosphate.
Question
When a muscle cell generates tension but does not shorten,a(n)______ contraction occurs.

A)isometric
B)isotonic
C)spastic
D)flaccid
Question
Skeletal muscles at rest obtain most of their energy from the aerobic respiration of

A)glucose.
B)protein.
C)fatty acids.
D)glycogen.
Question
Which of the following statements about muscles is FALSE?

A)During isometric contractions muscles do not generate tension.
B)The strength of contraction is directly proportional to the stimulus intensity.
C)Tendons act as part of the series-elastic component of a muscle.
D)During muscle contraction the Z disks move closer together.
Question
Which of the following is NOT true about the series-elastic component to contraction?

A)It absorbs some of the tension of muscle contraction.
B)It provides for elastic recoil when muscles relax.
C)It must loosen for a muscle to shorten.
D)It is provided by tendons.
Question
The staircase effect or _____ represents a warm up effect due to increasing intracellular calcium concentrations.

A)treppe
B)tetanus
C)incomplete tetanus
D)tonus
Question
_______ refer to muscle contractions that produce a shortening muscle with a constant contraction strength at a given load.

A)Treppe contractions
B)Isotonic contractions
C)Twitch contractions
D)Isometric contractions
Question
Insertion of ______________ in the muscle cell membrane increases cellular glucose uptake.

A)GLUT1
B)GLUT2
C)GLUT3
D)GLUT4
Question
Which of the following does NOT increase the strength of the muscle contraction?

A)a high number of fibers stimulated
B)increased frequency of stimulation
C)thicker muscle fiber
D)resting sarcomere length of 3.6µm
Question
A force-velocity curve shows the _______ relationship between the force opposing muscle contraction and the velocity of muscle shortening.

A)direct
B)inverse
C)increased
D)no
Question
Which of the following is true for the first 30 minutes of heavy exercise?

A)Most energy is derived from glycogen and plasma glucose.
B)The percentage of energy obtained from plasma free fatty acids exceeds that of mild exercise.
C)The percentage of energy obtain from plasma glucose is less than that of moderate exercise.
D)All apply.
Question
Smooth,sustained muscle contractions in vivo are due to synchronous activation of motor units.
Question
Blood lactate will begin to rise when exercise is performed at a rate that is

A)15% of VO2max.
B)25% of VO2max.
C)50% of VO2max.
D)85% of VO2max.
Question
A muscle contraction against a resistance that is greater than the force and causes muscle lengthening is a(n)

A)concentric contraction.
B)isometric contraction.
C)eccentric contraction.
D)isokinetic contraction.
Question
Exceeding the VO2max will result in lactate production by the muscle.
Question
In regards to the relationship between resting muscle fiber length and tension generated,

A)maximal tension is generated when the thick and thin filaments slightly overlap.
B)maximal tension is generated when the thick and thin filaments do not overlap.
C)maximal tension is generated when the thick and thin filaments greatly overlap.
D)the amount of overlap is unimportant in determining maximal tension.
Question
For a muscle to contract,it must overcome stronger opposing forces.
Question
The first 1 to 2 minutes of moderate to heavy exercise relies on _____ for ATP production.

A)aerobic respiration of glucose
B)anaerobic respiration of glucose
C)aerobic respiration of fatty acids
D)anaerobic respiration of amino acids
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Deck 12: Muscle: Mechanisms of Contraction and Neural Control
1
The biceps brachii causes flexion of the elbow.The triceps brachii causes extension of the elbow,so it would be a/an

A)abductor.
B)antagonist.
C)agonist.
D)levator.
B
2
Skeletal muscles with a low innervation ratio have a low degree of neural control.
False
3
The light band of a skeletal muscle is known as the

A)A band.
B)Z disc.
C)I band.
D)H banD.
C
4
The specialized region of the sarcolemma at the neuromuscular junction is called the

A)syncytium.
B)varicosity.
C)fascicle.
D)motor end plate.
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k this deck
5
Skeletal muscle cells are multinucleated.This is called a/an

A)myoblast.
B)striation.
C)syncytium.
D)endomysium.
Unlock Deck
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Unlock Deck
k this deck
6
The origin is the point of muscle attachment that is most stationary.
Unlock Deck
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k this deck
7
The more movable bony attachment is the

A)flexor.
B)origin.
C)extensor.
D)insertion.
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Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
8
Duchenne's muscular dystrophy

A)is an X-linked recessive trait.
B)most often affects women.
C)involves degeneration of the smooth muscle dense bodies.
D)All apply.
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Unlock Deck
k this deck
9
Longer,stronger muscles have motor units with very few fibers.
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k this deck
10
The prime mover of any skeletal movement is called the

A)flexor.
B)agonist.
C)abductor.
D)antagonist.
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k this deck
11
The deadly botulinum toxin can be used in the cosmetic treatment of skin wrinkles because it produces a flaccid paralysis.
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k this deck
12
Flexors increase the angle at a joint.
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13
Motor unit recruitment allows for _________ contraction strength.

A)increased
B)decreased
C)no change in
Unlock Deck
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14
The epimysium surrounds the individual muscle cells.
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15
A muscle that constricts an opening is a/an

A)extensor.
B)levator.
C)antagonist.
D)sphincter.
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k this deck
16
Z discs are found bisecting the A bands.
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k this deck
17
Each fascicle of a muscle is surrounded by the

A)perimysium.
B)epimysium.
C)endomysium.
D)sarcolemma.
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k this deck
18
Muscles which move a limb away the midline of the body are termed as

A)abductor muscles.
B)adductor muscles.
C)extensor muscles.
D)flexor muscles.
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k this deck
19
When skeletal muscle cells contract,they increase in length.
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20
Which of the following is needed for the myosin head to undergo a power stroke?

A)release of Pi
B)binding of ATP to the head
C)splitting of ATP into ADP and Pi
D)addition of Ca2+ to the head
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k this deck
21
During skeletal muscle contraction,adjacent _________ are pulled closer together as the _______ between them shorten.

A)A bands;I bands
B)I bands;A bands
C)Z disks;A bands
D)Z disks;M lines
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22
Thin filaments are composed of myosin and tropomyosin.
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23
What protein primarily makes up the thin filament?

A)actin
B)myosin
C)titin
D)Z-discs
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k this deck
24
Subunits of skeletal muscle cells that are composed of sarcomeres are called

A)myofibrils.
B)myofilaments.
C)sarcolemmas.
D)transverse tubules.
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25
During skeletal muscle contraction the A band decreases in size.
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26
What structure is composed of protein filaments and is located in the center of the thick filaments?

A)Z disk
B)titin
C)M line
D)actin
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k this deck
27
What enzyme is needed to start the cross bridging process?

A)creatine phosphatase
B)kinase
C)myosin ATPase
D)Ca2+ATPase
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k this deck
28
What muscle structural and functional unit runs from Z disc to Z disc?

A)A band
B)I band
C)sarcomere
D)myofibril
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k this deck
29
What protein primarily makes up the thick filament?

A)actin
B)myosin
C)titin
D)troponin
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k this deck
30
Myosin contains binding sites for ______________ and _____________.

A)sodium,calcium.
B)troponin,ATP.
C)ATP,actin.
D)actin,calcium.
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31
Myosin will not bind to actin unless ADP is bound to the myosin head.
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32
Cross-bridge formation occurs when myosin heads attach to actin molecules located in the thin filaments.
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33
The thick filament is also called the

A)A band.
B)I band.
C)H band.
D)M line.
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34
What is the lighter area in the center of the A-band called?

A)M-line
B)titin
C)Z-disc
D)H band
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35
Each somatic motor neuron with all the muscle fibers it innervates is a

A)fascicle.
B)varicosity.
C)motor unit.
D)sarcolemma.
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k this deck
36
What structure runs the length of the sarcomere and contributes to the elastic recoil in muscle?

A)Z disk
B)titin
C)M line
D)actin
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k this deck
37
Sarcomeres contain elastic titin filaments which help the muscles return to their resting length during muscle relaxation.
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k this deck
38
Somatic motor neurons release the neurotransmitter _________ at the neuromuscular junction.

A)dopamine
B)acetylcholine
C)norepinephrine
D)serotonin
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k this deck
39
The thick filament is split by a Z disc.
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40
The pumps that actively transport calcium back into the _______ are called Ca2+ -ATPase pumps.

A)transverse tubules
B)sarcoplasmic reticulum
C)neuromuscular junction
D)None apply.
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41
What is the role of ATP in muscle contraction and relaxation?

A)It is hydrolyzed from the myosin head to attach to actin.
B)It causes myosin head to detach from actin.
C)It powers the Ca2+ pumps to return Ca2+ to the SR.
D)All apply.
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42
The actin filament is a polymer formed from 300 to 400 globular subunits called

A)I-actin.
B)T-actin.
C)G-actin.
D)C-actin.
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43
The process by which action potentials cause muscle contraction is

A)the sliding filament theory.
B)excitation-contraction coupling.
C)the electromechanical release mechanism.
D)Both excitation-contraction coupling and the electromechanical release mechanism.
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Unlock Deck
k this deck
44
During skeletal muscle contraction,

A)the H band increases in size.
B)Ca2+ associates with tropomyosin.
C)myosin heads interact with tropomyosin.
D)thin filaments slide across thick filaments.
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k this deck
45
The _________ complex contains three proteins designated as the I,T,and C types.

A)actin
B)myosin
C)tropomyosin
D)troponin
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k this deck
46
The inability of muscle cells to relax due to high frequency stimulation is termed

A)treppe.
B)recruitment.
C)twitch.
D)tetanus.
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Unlock Deck
k this deck
47
Which of the following molecules is NOT part of the thin filament?

A)actin
B)titin
C)troponin
D)tropomyosin
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k this deck
48
What structures carry the action potentials into the interior of the muscle to cause muscle contraction?

A)T tubules
B)terminal cisternae
C)sarcoplasmic reticula
D)ryanodine receptors
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Unlock Deck
k this deck
49
When a muscle is stimulated to contract,calcium release channels in the SR will release Ca2+ by

A)active transport.
B)facilitated diffusion.
C)passive diffusion.
D)exocytosis.
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k this deck
50
Which molecule blocks the myosin head from binding to actin in a relaxed muscle?

A)tropomyosin
B)troponin
C)calcium
D)titin
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k this deck
51
Which of the following is NOT true of the relaxation of a muscle fiber?

A)ATP is needed to fuel the calcium pumps
B)calcium release channels close
C)the action potential must continue
D)Ca2+ moves from the sarcoplasm to the sarcoplasmic reticula
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52
Ca2+ must bind to tropomyosin so that the myosin binding sites on actin will be accessible to the myosin.
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53
The Ca2+ required for skeletal muscle contraction

A)is released from the sarcoplasmic reticulum.
B)enters the cell due to the opening of voltage regulated Ca2+ channels from the T tubules.
C)is actively transported into the cell.
D)is released from mitochondria.
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54
Which of the following does NOT occur during the cross bridge cycle?

A)a second ATP binding causes cross bridges to release.
B)ADP is released at the end of the power stroke.
C)energized myosin heads bind troponin.
D)ATP hydrolysis allows for cross bridge formation.
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55
Transverse tubules contain voltage-gated calcium channels that respond to membrane depolarization and are directly coupled to the calcium release channels in the sarcoplasmic reticulum.
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56
________ is characterized by continued attachment of myosin heads to actin filaments due to a lack of ATP.

A)Tetanus
B)Rigor mortis
C)Flaccid paralysis
D)Treppe
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k this deck
57
Increasing the frequency of action potentials in a somatic motor neuron will induce increased force of muscle contraction.
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k this deck
58
The movement of the troponin-tropomyosin complex requires

A)ATP.
B)Ca2+.
C)acetylcholine.
D)Na+.
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k this deck
59
Summation occurs in muscle cells when stimulus frequency increases to produce a greater force contraction.
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k this deck
60
A shortening of the muscle that occurs when the tension is greater than the load is a(n)

A)concentric contraction.
B)isometric contraction.
C)eccentric contraction.
D)isokinetic contraction.
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Unlock Deck
k this deck
61
Isotonic muscle contractions are often preceded by isometric contractions.
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k this deck
62
ATP in muscle contraction is needed for

A)attachment of myosin cross bridges to actin.
B)release of myosin cross bridges from actin.
C)pumping of Ca2+ back into the sarcoplasmic reticulum.
D)All apply.
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k this deck
63
High-energy phosphates are stored in skeletal muscle as creatine phosphate.
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64
When a muscle cell generates tension but does not shorten,a(n)______ contraction occurs.

A)isometric
B)isotonic
C)spastic
D)flaccid
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65
Skeletal muscles at rest obtain most of their energy from the aerobic respiration of

A)glucose.
B)protein.
C)fatty acids.
D)glycogen.
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66
Which of the following statements about muscles is FALSE?

A)During isometric contractions muscles do not generate tension.
B)The strength of contraction is directly proportional to the stimulus intensity.
C)Tendons act as part of the series-elastic component of a muscle.
D)During muscle contraction the Z disks move closer together.
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67
Which of the following is NOT true about the series-elastic component to contraction?

A)It absorbs some of the tension of muscle contraction.
B)It provides for elastic recoil when muscles relax.
C)It must loosen for a muscle to shorten.
D)It is provided by tendons.
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68
The staircase effect or _____ represents a warm up effect due to increasing intracellular calcium concentrations.

A)treppe
B)tetanus
C)incomplete tetanus
D)tonus
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69
_______ refer to muscle contractions that produce a shortening muscle with a constant contraction strength at a given load.

A)Treppe contractions
B)Isotonic contractions
C)Twitch contractions
D)Isometric contractions
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70
Insertion of ______________ in the muscle cell membrane increases cellular glucose uptake.

A)GLUT1
B)GLUT2
C)GLUT3
D)GLUT4
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71
Which of the following does NOT increase the strength of the muscle contraction?

A)a high number of fibers stimulated
B)increased frequency of stimulation
C)thicker muscle fiber
D)resting sarcomere length of 3.6µm
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72
A force-velocity curve shows the _______ relationship between the force opposing muscle contraction and the velocity of muscle shortening.

A)direct
B)inverse
C)increased
D)no
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73
Which of the following is true for the first 30 minutes of heavy exercise?

A)Most energy is derived from glycogen and plasma glucose.
B)The percentage of energy obtained from plasma free fatty acids exceeds that of mild exercise.
C)The percentage of energy obtain from plasma glucose is less than that of moderate exercise.
D)All apply.
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74
Smooth,sustained muscle contractions in vivo are due to synchronous activation of motor units.
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75
Blood lactate will begin to rise when exercise is performed at a rate that is

A)15% of VO2max.
B)25% of VO2max.
C)50% of VO2max.
D)85% of VO2max.
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76
A muscle contraction against a resistance that is greater than the force and causes muscle lengthening is a(n)

A)concentric contraction.
B)isometric contraction.
C)eccentric contraction.
D)isokinetic contraction.
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77
Exceeding the VO2max will result in lactate production by the muscle.
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78
In regards to the relationship between resting muscle fiber length and tension generated,

A)maximal tension is generated when the thick and thin filaments slightly overlap.
B)maximal tension is generated when the thick and thin filaments do not overlap.
C)maximal tension is generated when the thick and thin filaments greatly overlap.
D)the amount of overlap is unimportant in determining maximal tension.
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79
For a muscle to contract,it must overcome stronger opposing forces.
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80
The first 1 to 2 minutes of moderate to heavy exercise relies on _____ for ATP production.

A)aerobic respiration of glucose
B)anaerobic respiration of glucose
C)aerobic respiration of fatty acids
D)anaerobic respiration of amino acids
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