Deck 12: Muscle: Mechanisms of Contraction and Neural Control

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Question
Z discs are found bisecting the A bands.
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Question
The more movable bony attachment is the

A)flexor.
B)origin.
C)extensor.
D)insertion.
Question
The origin is the point of muscle attachment that is most stationary.
Question
The light band of a skeletal muscle is known as the

A)A band.
B)Z disc.
C)I band.
D)H banD.
Question
A muscle that constricts an opening is a/an

A)extensor.
B)levator.
C)antagonist.
D)sphincter.
Question
Muscles which move a limb away the midline of the body are termed as

A)abductor muscles.
B)adductor muscles.
C)extensor muscles.
D)flexor muscles.
Question
When skeletal muscle cells contract,they increase in length.
Question
The biceps brachii causes flexion of the elbow.The triceps brachii causes extension of the elbow,so it would be a/an

A)abductor.
B)antagonist.
C)agonist.
D)levator.
Question
The deadly botulinum toxin can be used in the cosmetic treatment of skin wrinkles because it produces a flaccid paralysis.
Question
Skeletal muscles with a low innervation ratio have a low degree of neural control.
Question
The prime mover of any skeletal movement is called the

A)flexor.
B)agonist.
C)abductor.
D)antagonist.
Question
Skeletal muscle cells are multinucleated.This is called a/an

A)myoblast.
B)striation.
C)syncytium.
D)endomysium.
Question
Each fascicle of a muscle is surrounded by the

A)perimysium.
B)epimysium.
C)endomysium.
D)sarcolemma.
Question
The specialized region of the sarcolemma at the neuromuscular junction is called the

A)syncytium.
B)varicosity.
C)fascicle.
D)motor end plate.
Question
The epimysium surrounds the individual muscle cells.
Question
Longer,stronger muscles have motor units with very few fibers.
Question
Duchenne's muscular dystrophy

A)is an X-linked recessive trait.
B)most often affects women.
C)involves degeneration of the smooth muscle dense bodies.
D)All apply.
Question
Motor unit recruitment allows for _________ contraction strength.

A)increased
B)decreased
C)no change in
Question
Flexors increase the angle at a joint.
Question
Each somatic motor neuron with all the muscle fibers it innervates is a

A)fascicle.
B)varicosity.
C)motor unit.
D)sarcolemma.
Question
Thin filaments are composed of myosin and tropomyosin.
Question
Cross-bridge formation occurs when myosin heads attach to actin molecules located in the thin filaments.
Question
What structure is composed of protein filaments and is located in the center of the thick filaments?

A)Z disk
B)titin
C)M line
D)actin
Question
During skeletal muscle contraction the A band decreases in size.
Question
What protein primarily makes up the thick filament?

A)actin
B)myosin
C)titin
D)troponin
Question
Myosin will not bind to actin unless ADP is bound to the myosin head.
Question
Myosin contains binding sites for ______________ and _____________.

A)sodium,calcium.
B)troponin,ATP.
C)ATP,actin.
D)actin,calcium.
Question
What enzyme is needed to start the cross bridging process?

A)creatine phosphatase
B)kinase
C)myosin ATPase
D)Ca2+ATPase
Question
The thick filament is split by a Z disc.
Question
Somatic motor neurons release the neurotransmitter _________ at the neuromuscular junction.

A)dopamine
B)acetylcholine
C)norepinephrine
D)serotonin
Question
What protein primarily makes up the thin filament?

A)actin
B)myosin
C)titin
D)Z-discs
Question
Sarcomeres contain elastic titin filaments which help the muscles return to their resting length during muscle relaxation.
Question
What structure runs the length of the sarcomere and contributes to the elastic recoil in muscle?

A)Z disk
B)titin
C)M line
D)actin
Question
What is the lighter area in the center of the A-band called?

A)M-line
B)titin
C)Z-disc
D)H band
Question
Subunits of skeletal muscle cells that are composed of sarcomeres are called

A)myofibrils.
B)myofilaments.
C)sarcolemmas.
D)transverse tubules.
Question
The thick filament is also called the

A)A band.
B)I band.
C)H band.
D)M line.
Question
During skeletal muscle contraction,adjacent _________ are pulled closer together as the _______ between them shorten.

A)A bands;I bands
B)I bands;A bands
C)Z disks;A bands
D)Z disks;M lines
Question
Which of the following is needed for the myosin head to undergo a power stroke?

A)release of Pi
B)binding of ATP to the head
C)splitting of ATP into ADP and Pi
D)addition of Ca2+ to the head
Question
What muscle structural and functional unit runs from Z disc to Z disc?

A)A band
B)I band
C)sarcomere
D)myofibril
Question
The _________ complex contains three proteins designated as the I,T,and C types.

A)actin
B)myosin
C)tropomyosin
D)troponin
Question
What is the role of ATP in muscle contraction and relaxation?

A)It is hydrolyzed from the myosin head to attach to actin.
B)It causes myosin head to detach from actin.
C)It powers the Ca2+ pumps to return Ca2+ to the SR.
D)All apply.
Question
What structures carry the action potentials into the interior of the muscle to cause muscle contraction?

A)T tubules
B)terminal cisternae
C)sarcoplasmic reticula
D)ryanodine receptors
Question
Transverse tubules contain voltage-gated calcium channels that respond to membrane depolarization and are directly coupled to the calcium release channels in the sarcoplasmic reticulum.
Question
When a muscle is stimulated to contract,calcium release channels in the SR will release Ca2+ by

A)active transport.
B)facilitated diffusion.
C)passive diffusion.
D)exocytosis.
Question
The inability of muscle cells to relax due to high frequency stimulation is termed

A)treppe.
B)recruitment.
C)twitch.
D)tetanus.
Question
Ca2+ must bind to tropomyosin so that the myosin binding sites on actin will be accessible to the myosin.
Question
Which molecule blocks the myosin head from binding to actin in a relaxed muscle?

A)tropomyosin
B)troponin
C)calcium
D)titin
Question
The Ca2+ required for skeletal muscle contraction

A)is released from the sarcoplasmic reticulum.
B)enters the cell due to the opening of voltage regulated Ca2+ channels from the T tubules.
C)is actively transported into the cell.
D)is released from mitochondria.
Question
The movement of the troponin-tropomyosin complex requires

A)ATP.
B)Ca2+.
C)acetylcholine.
D)Na+.
Question
Increasing the frequency of action potentials in a somatic motor neuron will induce increased force of muscle contraction.
Question
The process by which action potentials cause muscle contraction is

A)the sliding filament theory.
B)excitation-contraction coupling.
C)the electromechanical release mechanism.
D)Both excitation-contraction coupling and the electromechanical release mechanism.
Question
Which of the following is NOT true of the relaxation of a muscle fiber?

A)ATP is needed to fuel the calcium pumps
B)calcium release channels close
C)the action potential must continue
D)Ca2+ moves from the sarcoplasm to the sarcoplasmic reticula
Question
Which of the following does NOT occur during the cross bridge cycle?

A)a second ATP binding causes cross bridges to release.
B)ADP is released at the end of the power stroke.
C)energized myosin heads bind troponin.
D)ATP hydrolysis allows for cross bridge formation.
Question
The actin filament is a polymer formed from 300 to 400 globular subunits called

A)I-actin.
B)T-actin.
C)G-actin.
D)C-actin.
Question
The pumps that actively transport calcium back into the _______ are called Ca2+ -ATPase pumps.

A)transverse tubules
B)sarcoplasmic reticulum
C)neuromuscular junction
D)None apply.
Question
Summation occurs in muscle cells when stimulus frequency increases to produce a greater force contraction.
Question
________ is characterized by continued attachment of myosin heads to actin filaments due to a lack of ATP.

A)Tetanus
B)Rigor mortis
C)Flaccid paralysis
D)Treppe
Question
During skeletal muscle contraction,

A)the H band increases in size.
B)Ca2+ associates with tropomyosin.
C)myosin heads interact with tropomyosin.
D)thin filaments slide across thick filaments.
Question
Which of the following molecules is NOT part of the thin filament?

A)actin
B)titin
C)troponin
D)tropomyosin
Question
When a muscle cell generates tension but does not shorten,a(n)______ contraction occurs.

A)isometric
B)isotonic
C)spastic
D)flaccid
Question
ATP in muscle contraction is needed for

A)attachment of myosin cross bridges to actin.
B)release of myosin cross bridges from actin.
C)pumping of Ca2+ back into the sarcoplasmic reticulum.
D)All apply.
Question
Skeletal muscles at rest obtain most of their energy from the aerobic respiration of

A)glucose.
B)protein.
C)fatty acids.
D)glycogen.
Question
A shortening of the muscle that occurs when the tension is greater than the load is a(n)

A)concentric contraction.
B)isometric contraction.
C)eccentric contraction.
D)isokinetic contraction.
Question
Blood lactate will begin to rise when exercise is performed at a rate that is

A)15% of VO2max.
B)25% of VO2max.
C)50% of VO2max.
D)85% of VO2max.
Question
Isotonic muscle contractions are often preceded by isometric contractions.
Question
In regards to the relationship between resting muscle fiber length and tension generated,

A)maximal tension is generated when the thick and thin filaments slightly overlap.
B)maximal tension is generated when the thick and thin filaments do not overlap.
C)maximal tension is generated when the thick and thin filaments greatly overlap.
D)the amount of overlap is unimportant in determining maximal tension.
Question
Which of the following is NOT true about the series-elastic component to contraction?

A)It absorbs some of the tension of muscle contraction.
B)It provides for elastic recoil when muscles relax.
C)It must loosen for a muscle to shorten.
D)It is provided by tendons.
Question
A force-velocity curve shows the _______ relationship between the force opposing muscle contraction and the velocity of muscle shortening.

A)direct
B)inverse
C)increased
D)no
Question
High-energy phosphates are stored in skeletal muscle as creatine phosphate.
Question
_______ refer to muscle contractions that produce a shortening muscle with a constant contraction strength at a given load.

A)Treppe contractions
B)Isotonic contractions
C)Twitch contractions
D)Isometric contractions
Question
The staircase effect or _____ represents a warm up effect due to increasing intracellular calcium concentrations.

A)treppe
B)tetanus
C)incomplete tetanus
D)tonus
Question
Which of the following does NOT increase the strength of the muscle contraction?

A)a high number of fibers stimulated
B)increased frequency of stimulation
C)thicker muscle fiber
D)resting sarcomere length of 3.6µm
Question
Smooth,sustained muscle contractions in vivo are due to synchronous activation of motor units.
Question
A muscle contraction against a resistance that is greater than the force and causes muscle lengthening is a(n)

A)concentric contraction.
B)isometric contraction.
C)eccentric contraction.
D)isokinetic contraction.
Question
Which of the following statements about muscles is FALSE?

A)During isometric contractions muscles do not generate tension.
B)The strength of contraction is directly proportional to the stimulus intensity.
C)Tendons act as part of the series-elastic component of a muscle.
D)During muscle contraction the Z disks move closer together.
Question
Which of the following is true for the first 30 minutes of heavy exercise?

A)Most energy is derived from glycogen and plasma glucose.
B)The percentage of energy obtained from plasma free fatty acids exceeds that of mild exercise.
C)The percentage of energy obtain from plasma glucose is less than that of moderate exercise.
D)All apply.
Question
Insertion of ______________ in the muscle cell membrane increases cellular glucose uptake.

A)GLUT1
B)GLUT2
C)GLUT3
D)GLUT4
Question
For a muscle to contract,it must overcome stronger opposing forces.
Question
Exceeding the VO2max will result in lactate production by the muscle.
Question
An increase in plasma creatine phosphokinase could indicate

A)muscular dystrophy.
B)liver disease.
C)heart attack.
D)Both muscular dystrophy and heart attack.
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Deck 12: Muscle: Mechanisms of Contraction and Neural Control
1
Z discs are found bisecting the A bands.
False
2
The more movable bony attachment is the

A)flexor.
B)origin.
C)extensor.
D)insertion.
D
3
The origin is the point of muscle attachment that is most stationary.
True
4
The light band of a skeletal muscle is known as the

A)A band.
B)Z disc.
C)I band.
D)H banD.
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Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
5
A muscle that constricts an opening is a/an

A)extensor.
B)levator.
C)antagonist.
D)sphincter.
Unlock Deck
Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
6
Muscles which move a limb away the midline of the body are termed as

A)abductor muscles.
B)adductor muscles.
C)extensor muscles.
D)flexor muscles.
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Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
7
When skeletal muscle cells contract,they increase in length.
Unlock Deck
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Unlock Deck
k this deck
8
The biceps brachii causes flexion of the elbow.The triceps brachii causes extension of the elbow,so it would be a/an

A)abductor.
B)antagonist.
C)agonist.
D)levator.
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k this deck
9
The deadly botulinum toxin can be used in the cosmetic treatment of skin wrinkles because it produces a flaccid paralysis.
Unlock Deck
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Unlock Deck
k this deck
10
Skeletal muscles with a low innervation ratio have a low degree of neural control.
Unlock Deck
Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
11
The prime mover of any skeletal movement is called the

A)flexor.
B)agonist.
C)abductor.
D)antagonist.
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Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
12
Skeletal muscle cells are multinucleated.This is called a/an

A)myoblast.
B)striation.
C)syncytium.
D)endomysium.
Unlock Deck
Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
13
Each fascicle of a muscle is surrounded by the

A)perimysium.
B)epimysium.
C)endomysium.
D)sarcolemma.
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k this deck
14
The specialized region of the sarcolemma at the neuromuscular junction is called the

A)syncytium.
B)varicosity.
C)fascicle.
D)motor end plate.
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k this deck
15
The epimysium surrounds the individual muscle cells.
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k this deck
16
Longer,stronger muscles have motor units with very few fibers.
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k this deck
17
Duchenne's muscular dystrophy

A)is an X-linked recessive trait.
B)most often affects women.
C)involves degeneration of the smooth muscle dense bodies.
D)All apply.
Unlock Deck
Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
18
Motor unit recruitment allows for _________ contraction strength.

A)increased
B)decreased
C)no change in
Unlock Deck
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k this deck
19
Flexors increase the angle at a joint.
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k this deck
20
Each somatic motor neuron with all the muscle fibers it innervates is a

A)fascicle.
B)varicosity.
C)motor unit.
D)sarcolemma.
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Unlock Deck
k this deck
21
Thin filaments are composed of myosin and tropomyosin.
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k this deck
22
Cross-bridge formation occurs when myosin heads attach to actin molecules located in the thin filaments.
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k this deck
23
What structure is composed of protein filaments and is located in the center of the thick filaments?

A)Z disk
B)titin
C)M line
D)actin
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k this deck
24
During skeletal muscle contraction the A band decreases in size.
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k this deck
25
What protein primarily makes up the thick filament?

A)actin
B)myosin
C)titin
D)troponin
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26
Myosin will not bind to actin unless ADP is bound to the myosin head.
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27
Myosin contains binding sites for ______________ and _____________.

A)sodium,calcium.
B)troponin,ATP.
C)ATP,actin.
D)actin,calcium.
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28
What enzyme is needed to start the cross bridging process?

A)creatine phosphatase
B)kinase
C)myosin ATPase
D)Ca2+ATPase
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k this deck
29
The thick filament is split by a Z disc.
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k this deck
30
Somatic motor neurons release the neurotransmitter _________ at the neuromuscular junction.

A)dopamine
B)acetylcholine
C)norepinephrine
D)serotonin
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Unlock Deck
k this deck
31
What protein primarily makes up the thin filament?

A)actin
B)myosin
C)titin
D)Z-discs
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Unlock Deck
k this deck
32
Sarcomeres contain elastic titin filaments which help the muscles return to their resting length during muscle relaxation.
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Unlock Deck
k this deck
33
What structure runs the length of the sarcomere and contributes to the elastic recoil in muscle?

A)Z disk
B)titin
C)M line
D)actin
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k this deck
34
What is the lighter area in the center of the A-band called?

A)M-line
B)titin
C)Z-disc
D)H band
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k this deck
35
Subunits of skeletal muscle cells that are composed of sarcomeres are called

A)myofibrils.
B)myofilaments.
C)sarcolemmas.
D)transverse tubules.
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36
The thick filament is also called the

A)A band.
B)I band.
C)H band.
D)M line.
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37
During skeletal muscle contraction,adjacent _________ are pulled closer together as the _______ between them shorten.

A)A bands;I bands
B)I bands;A bands
C)Z disks;A bands
D)Z disks;M lines
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38
Which of the following is needed for the myosin head to undergo a power stroke?

A)release of Pi
B)binding of ATP to the head
C)splitting of ATP into ADP and Pi
D)addition of Ca2+ to the head
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39
What muscle structural and functional unit runs from Z disc to Z disc?

A)A band
B)I band
C)sarcomere
D)myofibril
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40
The _________ complex contains three proteins designated as the I,T,and C types.

A)actin
B)myosin
C)tropomyosin
D)troponin
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41
What is the role of ATP in muscle contraction and relaxation?

A)It is hydrolyzed from the myosin head to attach to actin.
B)It causes myosin head to detach from actin.
C)It powers the Ca2+ pumps to return Ca2+ to the SR.
D)All apply.
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42
What structures carry the action potentials into the interior of the muscle to cause muscle contraction?

A)T tubules
B)terminal cisternae
C)sarcoplasmic reticula
D)ryanodine receptors
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43
Transverse tubules contain voltage-gated calcium channels that respond to membrane depolarization and are directly coupled to the calcium release channels in the sarcoplasmic reticulum.
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k this deck
44
When a muscle is stimulated to contract,calcium release channels in the SR will release Ca2+ by

A)active transport.
B)facilitated diffusion.
C)passive diffusion.
D)exocytosis.
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Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
45
The inability of muscle cells to relax due to high frequency stimulation is termed

A)treppe.
B)recruitment.
C)twitch.
D)tetanus.
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Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
46
Ca2+ must bind to tropomyosin so that the myosin binding sites on actin will be accessible to the myosin.
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k this deck
47
Which molecule blocks the myosin head from binding to actin in a relaxed muscle?

A)tropomyosin
B)troponin
C)calcium
D)titin
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Unlock Deck
k this deck
48
The Ca2+ required for skeletal muscle contraction

A)is released from the sarcoplasmic reticulum.
B)enters the cell due to the opening of voltage regulated Ca2+ channels from the T tubules.
C)is actively transported into the cell.
D)is released from mitochondria.
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Unlock Deck
k this deck
49
The movement of the troponin-tropomyosin complex requires

A)ATP.
B)Ca2+.
C)acetylcholine.
D)Na+.
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Unlock Deck
k this deck
50
Increasing the frequency of action potentials in a somatic motor neuron will induce increased force of muscle contraction.
Unlock Deck
Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
51
The process by which action potentials cause muscle contraction is

A)the sliding filament theory.
B)excitation-contraction coupling.
C)the electromechanical release mechanism.
D)Both excitation-contraction coupling and the electromechanical release mechanism.
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Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
52
Which of the following is NOT true of the relaxation of a muscle fiber?

A)ATP is needed to fuel the calcium pumps
B)calcium release channels close
C)the action potential must continue
D)Ca2+ moves from the sarcoplasm to the sarcoplasmic reticula
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53
Which of the following does NOT occur during the cross bridge cycle?

A)a second ATP binding causes cross bridges to release.
B)ADP is released at the end of the power stroke.
C)energized myosin heads bind troponin.
D)ATP hydrolysis allows for cross bridge formation.
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54
The actin filament is a polymer formed from 300 to 400 globular subunits called

A)I-actin.
B)T-actin.
C)G-actin.
D)C-actin.
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Unlock Deck
k this deck
55
The pumps that actively transport calcium back into the _______ are called Ca2+ -ATPase pumps.

A)transverse tubules
B)sarcoplasmic reticulum
C)neuromuscular junction
D)None apply.
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Unlock Deck
k this deck
56
Summation occurs in muscle cells when stimulus frequency increases to produce a greater force contraction.
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k this deck
57
________ is characterized by continued attachment of myosin heads to actin filaments due to a lack of ATP.

A)Tetanus
B)Rigor mortis
C)Flaccid paralysis
D)Treppe
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Unlock Deck
k this deck
58
During skeletal muscle contraction,

A)the H band increases in size.
B)Ca2+ associates with tropomyosin.
C)myosin heads interact with tropomyosin.
D)thin filaments slide across thick filaments.
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k this deck
59
Which of the following molecules is NOT part of the thin filament?

A)actin
B)titin
C)troponin
D)tropomyosin
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k this deck
60
When a muscle cell generates tension but does not shorten,a(n)______ contraction occurs.

A)isometric
B)isotonic
C)spastic
D)flaccid
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k this deck
61
ATP in muscle contraction is needed for

A)attachment of myosin cross bridges to actin.
B)release of myosin cross bridges from actin.
C)pumping of Ca2+ back into the sarcoplasmic reticulum.
D)All apply.
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Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
62
Skeletal muscles at rest obtain most of their energy from the aerobic respiration of

A)glucose.
B)protein.
C)fatty acids.
D)glycogen.
Unlock Deck
Unlock for access to all 150 flashcards in this deck.
Unlock Deck
k this deck
63
A shortening of the muscle that occurs when the tension is greater than the load is a(n)

A)concentric contraction.
B)isometric contraction.
C)eccentric contraction.
D)isokinetic contraction.
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64
Blood lactate will begin to rise when exercise is performed at a rate that is

A)15% of VO2max.
B)25% of VO2max.
C)50% of VO2max.
D)85% of VO2max.
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65
Isotonic muscle contractions are often preceded by isometric contractions.
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66
In regards to the relationship between resting muscle fiber length and tension generated,

A)maximal tension is generated when the thick and thin filaments slightly overlap.
B)maximal tension is generated when the thick and thin filaments do not overlap.
C)maximal tension is generated when the thick and thin filaments greatly overlap.
D)the amount of overlap is unimportant in determining maximal tension.
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67
Which of the following is NOT true about the series-elastic component to contraction?

A)It absorbs some of the tension of muscle contraction.
B)It provides for elastic recoil when muscles relax.
C)It must loosen for a muscle to shorten.
D)It is provided by tendons.
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68
A force-velocity curve shows the _______ relationship between the force opposing muscle contraction and the velocity of muscle shortening.

A)direct
B)inverse
C)increased
D)no
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69
High-energy phosphates are stored in skeletal muscle as creatine phosphate.
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70
_______ refer to muscle contractions that produce a shortening muscle with a constant contraction strength at a given load.

A)Treppe contractions
B)Isotonic contractions
C)Twitch contractions
D)Isometric contractions
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71
The staircase effect or _____ represents a warm up effect due to increasing intracellular calcium concentrations.

A)treppe
B)tetanus
C)incomplete tetanus
D)tonus
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72
Which of the following does NOT increase the strength of the muscle contraction?

A)a high number of fibers stimulated
B)increased frequency of stimulation
C)thicker muscle fiber
D)resting sarcomere length of 3.6µm
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73
Smooth,sustained muscle contractions in vivo are due to synchronous activation of motor units.
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74
A muscle contraction against a resistance that is greater than the force and causes muscle lengthening is a(n)

A)concentric contraction.
B)isometric contraction.
C)eccentric contraction.
D)isokinetic contraction.
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75
Which of the following statements about muscles is FALSE?

A)During isometric contractions muscles do not generate tension.
B)The strength of contraction is directly proportional to the stimulus intensity.
C)Tendons act as part of the series-elastic component of a muscle.
D)During muscle contraction the Z disks move closer together.
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76
Which of the following is true for the first 30 minutes of heavy exercise?

A)Most energy is derived from glycogen and plasma glucose.
B)The percentage of energy obtained from plasma free fatty acids exceeds that of mild exercise.
C)The percentage of energy obtain from plasma glucose is less than that of moderate exercise.
D)All apply.
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77
Insertion of ______________ in the muscle cell membrane increases cellular glucose uptake.

A)GLUT1
B)GLUT2
C)GLUT3
D)GLUT4
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78
For a muscle to contract,it must overcome stronger opposing forces.
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79
Exceeding the VO2max will result in lactate production by the muscle.
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80
An increase in plasma creatine phosphokinase could indicate

A)muscular dystrophy.
B)liver disease.
C)heart attack.
D)Both muscular dystrophy and heart attack.
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