Deck 7: Bone Tissue
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Deck 7: Bone Tissue
1
Concentric lamellae within an osteon are connected by lacunae.
False
2
A radiograph (X-ray)of a child's hand will show epiphyseal lines.
False
3
Hypercalcemia is rare,but hypocalcemia can result from a wide variety of conditions.
True
4
The hemopoietic tissue in a bone is otherwise known as myeloid tissue.
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5
Most blood cells are produced in the red marrow of bones.
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6
Osteoid tissue is similar to bone except for a lack of minerals.
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7
Which of the following is not a function of the skeleton?
A) Storage of calcium and phosphate ions
B) Storage of red blood cells
C) Providing support for most muscles
D) Protecting the brain
E) Protecting the spinal cord
A) Storage of calcium and phosphate ions
B) Storage of red blood cells
C) Providing support for most muscles
D) Protecting the brain
E) Protecting the spinal cord
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8
Osteomalacia results in bone brittleness.
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9
Closed reduction is the surgical realignment of the parts of a broken bone.
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10
Osteoporosis often leads to an exaggerated thoracic spinal curvature,which is called kyphosis.
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11
Bones grow in diameter by interstitial growth.
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12
Osteogenic cells are bone stem cells that differentiate into osteoblasts and osteoclasts.
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13
The center cavity of the diaphysis of a long bone is called the __________.
A) marrow cavity
B) central canal
C) nutrient foramen
D) canaliculus
E) epiphysis
A) marrow cavity
B) central canal
C) nutrient foramen
D) canaliculus
E) epiphysis
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14
Parathyroid hormone (PTH)binds to receptors on osteoblasts.
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15
Intramembranous ossification is common in children,whereas endochondral ossification is typical in young adults.
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16
The thin layer of slightly denser spongy bone that separates an adult's epiphysis from the diaphysis is called the __________.
A) periosteum
B) metaphysis
C) growth plate
D) epiphyseal line
E) diaphyseal line
A) periosteum
B) metaphysis
C) growth plate
D) epiphyseal line
E) diaphyseal line
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17
Which of the following tissues is not found as part of a long bone?
A) Osseous tissue
B) Nervous tissue
C) Adipose tissue
D) Cartilage
E) Transitional epithelium
A) Osseous tissue
B) Nervous tissue
C) Adipose tissue
D) Cartilage
E) Transitional epithelium
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18
Hypercalcemia causes depression of the nervous system.
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19
A vertebra is considered a long bone.
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20
Osseous tissue is a(an)____________ tissue.
A) connective
B) epithelial
C) dense regular
D) dense irregular
E) reticular
A) connective
B) epithelial
C) dense regular
D) dense irregular
E) reticular
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21
What would you find in the marrow cavity of the diaphysis of an adult humerus (arm bone)?
A) Periosteum
B) Hemopoietic tissue
C) Red bone marrow
D) Yellow bone marrow
E) Compact bone
A) Periosteum
B) Hemopoietic tissue
C) Red bone marrow
D) Yellow bone marrow
E) Compact bone
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22
The cortex of the long bone's diaphysis is made of _________.
A) marrow
B) compact bone
C) spongy bone
D) dense regular connective tissue
E) articular cartilage
A) marrow
B) compact bone
C) spongy bone
D) dense regular connective tissue
E) articular cartilage
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23
The plasma membrane of __________ have a ruffled border with many deep infoldings,whereas __________ have long,thin,fingerlike cytoplasmic processes.
A) osteoclasts;osteocytes
B) osteocytes;osteoclasts
C) osteoblasts;osteoclasts
D) osteoblasts;osteocytes
E) osteocytes;osteogenic cells
A) osteoclasts;osteocytes
B) osteocytes;osteoclasts
C) osteoblasts;osteoclasts
D) osteoblasts;osteocytes
E) osteocytes;osteogenic cells
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24
In endochondral ossification,the precursor connective tissue is __________,which is replaced by bone.
A) embryonic mesenchyme
B) fibrous membranes
C) hyaline cartilage
D) transitional epithelium
E) fibrocartilage
A) embryonic mesenchyme
B) fibrous membranes
C) hyaline cartilage
D) transitional epithelium
E) fibrocartilage
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25
The expanded head at each end of a long bone is called the __________.
A) epiphysis
B) diaphysis
C) articular cartilage
D) periosteum
E) endosteum
A) epiphysis
B) diaphysis
C) articular cartilage
D) periosteum
E) endosteum
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26
Mature bones are remodeled throughout life via a process known as __________.
A) intramembranous ossification
B) endochondral ossification
C) interstitial growth
D) appositional growth
E) metaphysical growth
A) intramembranous ossification
B) endochondral ossification
C) interstitial growth
D) appositional growth
E) metaphysical growth
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27
It is common to find __________ in compact bone,but they are not seen in spongy bone.
A) lamellae
B) osteoclasts
C) lacunae
D) central canals
E) osteocytes
A) lamellae
B) osteoclasts
C) lacunae
D) central canals
E) osteocytes
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28
The __________ is a marginal zone of the epiphyseal plate where,in children and adolescents,bone can be seen replacing the hyaline cartilage.
A) metaphysis
B) primary ossification center
C) secondary ossification center
D) osteoid tissue
E) epiphyseal line
A) metaphysis
B) primary ossification center
C) secondary ossification center
D) osteoid tissue
E) epiphyseal line
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29
Spicules and trabeculae are found in __________.
A) compact bone
B) bone matrix
C) yellow bone marrow
D) red bone marrow
E) spongy bone
A) compact bone
B) bone matrix
C) yellow bone marrow
D) red bone marrow
E) spongy bone
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30
The spaces found within the concentric lamellae are called __________,and they contain __________.
A) canaliculi;osteoblasts
B) osteons;stem cells
C) lacunae;osteocytes
D) lacunae;osteoclasts
E) central canals;osteocytes
A) canaliculi;osteoblasts
B) osteons;stem cells
C) lacunae;osteocytes
D) lacunae;osteoclasts
E) central canals;osteocytes
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31
The hardness of bone comes from __________,whereas __________ provide(s)some degree of flexibility.
A) hydroxyapatite and other minerals;proteins
B) collagen and elastic fibers;minerals
C) glycoproteins;proteoglycans
D) calcium carbonate;calcium phosphate
E) proteins;collagen
A) hydroxyapatite and other minerals;proteins
B) collagen and elastic fibers;minerals
C) glycoproteins;proteoglycans
D) calcium carbonate;calcium phosphate
E) proteins;collagen
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32
Chondrocytes multiply in the zone of __________ of the metaphysis.
A) reserve cartilage
B) cell proliferation
C) cell hypertrophy
D) calcification
E) bone deposition
A) reserve cartilage
B) cell proliferation
C) cell hypertrophy
D) calcification
E) bone deposition
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33
A long bone is covered externally with a sheath called the __________,whereas the marrow cavity is lined with the __________.
A) epiphysis;diaphysis
B) diaphysis;epiphysis
C) compact bone;spongy bone
D) periosteum;endosteum
E) endosteum;periosteum
A) epiphysis;diaphysis
B) diaphysis;epiphysis
C) compact bone;spongy bone
D) periosteum;endosteum
E) endosteum;periosteum
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34
Red bone marrow does not contain __________.
A) myeloid tissue
B) yellow bone marrow
C) hemopoietic tissue
D) white blood cells
E) red blood cells
A) myeloid tissue
B) yellow bone marrow
C) hemopoietic tissue
D) white blood cells
E) red blood cells
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35
Bone-forming cells are called __________.
A) osteogenic (osteoprogenitor)cells
B) osteoblasts
C) osteoclasts
D) osteocytes
E) osteons
A) osteogenic (osteoprogenitor)cells
B) osteoblasts
C) osteoclasts
D) osteocytes
E) osteons
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36
Intramembranous ossification produces the __________.
A) irregular bones of the vertebrae
B) flat bones of the skull
C) long bones of the limbs
D) short bones of the wrist
E) short bones of the ankle
A) irregular bones of the vertebrae
B) flat bones of the skull
C) long bones of the limbs
D) short bones of the wrist
E) short bones of the ankle
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37
Which of the following is an inorganic component of the bone matrix?
A) Proteoglycans
B) Glycoproteins
C) Collagen
D) Hydroxyapatite
E) Glycosaminoglycans
A) Proteoglycans
B) Glycoproteins
C) Collagen
D) Hydroxyapatite
E) Glycosaminoglycans
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38
Achondroplastic dwarfism is a hereditary condition,in which the long bones of the limbs fail to elongate normally because of reduced hyperplasia and hypertrophy of cartilage in the __________.
A) primary ossification center
B) secondary ossification center
C) primary bone marrow
D) secondary bone marrow
E) epiphyseal plate
A) primary ossification center
B) secondary ossification center
C) primary bone marrow
D) secondary bone marrow
E) epiphyseal plate
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39
Which one of the following bone cells would have the greatest number of lysosomes?
A) Osteoblasts
B) Osteoclasts
C) Osteocytes
D) Osteogenic cells
E) Stem cells
A) Osteoblasts
B) Osteoclasts
C) Osteocytes
D) Osteogenic cells
E) Stem cells
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40
When ____________ become enclosed in lacunae,they become cells called _____________.
A) osteogenic cells;osteoblasts
B) osteoblasts;osteoclasts
C) osteoblasts;osteocytes
D) osteocytes;osteoclasts
E) osteocytes;osteoblasts
A) osteogenic cells;osteoblasts
B) osteoblasts;osteoclasts
C) osteoblasts;osteocytes
D) osteocytes;osteoclasts
E) osteocytes;osteoblasts
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41
Wolff's law of bone explains the effect of __________.
A) different diets on bone elongation
B) mechanical stress on bone remodeling
C) temperature on bone growth
D) age on bone thickening
E) sex on bone widening
A) different diets on bone elongation
B) mechanical stress on bone remodeling
C) temperature on bone growth
D) age on bone thickening
E) sex on bone widening
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42
Which of the following does not put women at risk for hypocalcemia?
A) Lactation
B) Pregnancy
C) Removal of the parathyroid glands
D) Removal of the thyroid gland
E) Lack of exposure to UV radiation
A) Lactation
B) Pregnancy
C) Removal of the parathyroid glands
D) Removal of the thyroid gland
E) Lack of exposure to UV radiation
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43
Phosphate is necessary for all of the following except __________.
A) ATP
B) DNA
C) phospholipids
D) RNA
E) amino acids
A) ATP
B) DNA
C) phospholipids
D) RNA
E) amino acids
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44
A soft callus forms during ___________.
A) endochondral ossification
B) intramembranous ossification
C) bone growth at the metaphysis
D) the remodeling of bone
E) the healing of a fracture
A) endochondral ossification
B) intramembranous ossification
C) bone growth at the metaphysis
D) the remodeling of bone
E) the healing of a fracture
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45
Which of the following is not a function of parathyroid hormone (PTH)?
A) Promote calcium reabsorption by the kidneys
B) Stimulate osteoclast activity
C) Lower blood calcium
D) Promote calcitriol synthesis
E) Inhibit osteoblast activity
A) Promote calcium reabsorption by the kidneys
B) Stimulate osteoclast activity
C) Lower blood calcium
D) Promote calcitriol synthesis
E) Inhibit osteoblast activity
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46
If a thyroid tumor secreted an excessive amount of calcitonin,we would expect ___________.
A) an elevated level of osteoclast activity
B) an elevated level of osteoblast activity
C) a reduced rate of endochondral ossification
D) a rise in blood calcium concentration
E) increasingly brittle bones
A) an elevated level of osteoclast activity
B) an elevated level of osteoblast activity
C) a reduced rate of endochondral ossification
D) a rise in blood calcium concentration
E) increasingly brittle bones
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47
Arteriosclerosis is one example of ectopic ossification,which means __________.
A) the solubility product has been reached
B) artery mineralization by osteoblasts
C) abnormal calcification of a tissue
D) accumulation of collagenous fibers in blood vessels
E) ossification of an entire blood vessel
A) the solubility product has been reached
B) artery mineralization by osteoblasts
C) abnormal calcification of a tissue
D) accumulation of collagenous fibers in blood vessels
E) ossification of an entire blood vessel
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48
Hypocalcemia can cause __________.
A) emotional disturbances
B) depression of the nervous system
C) muscle weakness
D) sluggish reflexes
E) muscle spasms
A) emotional disturbances
B) depression of the nervous system
C) muscle weakness
D) sluggish reflexes
E) muscle spasms
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49
Calcium plays an essential role in all of the following except __________.
A) muscle contraction
B) exocytosis
C) blood clotting
D) DNA synthesis
E) communication among neurons
A) muscle contraction
B) exocytosis
C) blood clotting
D) DNA synthesis
E) communication among neurons
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50
Osteoporosis is most common in elderly women because of the lack of ___________,which would otherwise inhibit ____________.
A) dietary calcium;estrogen production
B) osteoblasts;osteoclast activity
C) estrogen;osteoclast activity
D) parathyroid hormone;osteocyte activity
E) exercise;osteoblast activity
A) dietary calcium;estrogen production
B) osteoblasts;osteoclast activity
C) estrogen;osteoclast activity
D) parathyroid hormone;osteocyte activity
E) exercise;osteoblast activity
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51
A growing long bone in a child has only two areas of cartilage at the epiphysis.These two areas are the __________.
A) elastic cartilage and epiphyseal plate
B) epiphyseal plate and epiphyseal line
C) primary and secondary ossification centers
D) fibrocartilage and articular cartilage
E) articular cartilage and epiphyseal plate
A) elastic cartilage and epiphyseal plate
B) epiphyseal plate and epiphyseal line
C) primary and secondary ossification centers
D) fibrocartilage and articular cartilage
E) articular cartilage and epiphyseal plate
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52
Blood Ca2+ deficiency stimulates __________ secretion,which leads to __________.
A) calcitonin;more urinary phosphate reabsorption
B) calcitriol;more urinary phosphate excretion
C) parathyroid hormone;increased osteoclast activity
D) growth hormone;increased osteoblast activity
E) thyroid hormone;less urinary calcium excretion
A) calcitonin;more urinary phosphate reabsorption
B) calcitriol;more urinary phosphate excretion
C) parathyroid hormone;increased osteoclast activity
D) growth hormone;increased osteoblast activity
E) thyroid hormone;less urinary calcium excretion
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53
Bone protrudes through the skin in a fracture called __________.
A) complete
B) incomplete
C) closed
D) open
E) displaced
A) complete
B) incomplete
C) closed
D) open
E) displaced
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54
Bone elongation is a result of __________.
A) cartilage growth
B) muscle growth
C) osseous tissue growth
D) fibrous membrane addition
E) dense irregular connective tissue addition
A) cartilage growth
B) muscle growth
C) osseous tissue growth
D) fibrous membrane addition
E) dense irregular connective tissue addition
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55
Synthesized by the combined action of the skin,kidneys,and liver,_________ is important to the deposition of bone.
A) growth hormone
B) testosterone
C) estrogen
D) calcitonin
E) calcitriol
A) growth hormone
B) testosterone
C) estrogen
D) calcitonin
E) calcitriol
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56
Which of the following exemplifies a positive feedback process happening in bone mineral deposition?
A) The first few crystals that form attract more calcium and phosphate.
B) Osteoblasts neutralize inhibitors that prevent bone resorption.
C) Osteoclasts secrete acid phosphatase that digests collagen.
D) Collagen is digested by enzymes and hydroxyapatite by hydrochloric acid.
E) Solubility product is reached in the tissue fluids.
A) The first few crystals that form attract more calcium and phosphate.
B) Osteoblasts neutralize inhibitors that prevent bone resorption.
C) Osteoclasts secrete acid phosphatase that digests collagen.
D) Collagen is digested by enzymes and hydroxyapatite by hydrochloric acid.
E) Solubility product is reached in the tissue fluids.
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57
The process of dissolving bone and returning its minerals to the bloodstream is known as _________.
A) mineralization
B) mineral deposition
C) crystallization
D) resorption
E) ossification
A) mineralization
B) mineral deposition
C) crystallization
D) resorption
E) ossification
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58
The result of blood calcium and phosphate levels being too low for normal deposition is a softness of the bones called __________ in children and __________ in adults.
A) osteomalacia;rickets
B) rickets;osteomalacia
C) osteoporosis;osteomalacia
D) osteomyelitis;osteosarcoma
E) osteomyelitis;osteomalacia
A) osteomalacia;rickets
B) rickets;osteomalacia
C) osteoporosis;osteomalacia
D) osteomyelitis;osteosarcoma
E) osteomyelitis;osteomalacia
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59
A break in a bone that is already weakened by some other disease is called a(n)__________ fracture.
A) greenstick
B) open
C) closed
D) pathologic
E) displaced
A) greenstick
B) open
C) closed
D) pathologic
E) displaced
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60
A fracture in which the bone is broken into three or more pieces is called a __________ fracture.
A) linear
B) pott
C) comminuted
D) greenstick
E) compound
A) linear
B) pott
C) comminuted
D) greenstick
E) compound
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61
The most common bone disease is __________.
A) osteomyelitis
B) osteoporosis
C) osteosarcoma
D) osteomalacia
E) rickets
A) osteomyelitis
B) osteoporosis
C) osteosarcoma
D) osteomalacia
E) rickets
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62
The _____ is an example of bone as an organ;_____ bone is an example of bone as a tissue.
A) femur;spongy
B) spongy;femur
C) skull;marrow
D) compact;sesamoid
A) femur;spongy
B) spongy;femur
C) skull;marrow
D) compact;sesamoid
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63
Which of the following is the correct sequence of events in the healing of a bone fracture?
A) Bone remodeling → soft callus formation → hard callus formation → hematoma formation
B) Bone remodeling → hard callus formation → soft callus formation → hematoma formation
C) Hematoma formation → soft callus formation → hard callus formation → bone remodeling
D) Hematoma formation → hard callus formation → soft callus formation → bone remodeling
E) Soft callus formation → hard callus formation → hematoma formation → bone remodeling
A) Bone remodeling → soft callus formation → hard callus formation → hematoma formation
B) Bone remodeling → hard callus formation → soft callus formation → hematoma formation
C) Hematoma formation → soft callus formation → hard callus formation → bone remodeling
D) Hematoma formation → hard callus formation → soft callus formation → bone remodeling
E) Soft callus formation → hard callus formation → hematoma formation → bone remodeling
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64
Patches of fibrocartilage formed in the healing of a fracture are called __________,whereas the bony collar formed around the fracture is called __________.
A) fracture hematoma;granulation tissue
B) granulation tissue;soft callus
C) fracture hematoma;hard callus
D) granulation tissue;hard callus
E) soft callus;hard callus
A) fracture hematoma;granulation tissue
B) granulation tissue;soft callus
C) fracture hematoma;hard callus
D) granulation tissue;hard callus
E) soft callus;hard callus
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65
Bones,cartilage,and ligaments are tissues and organs of the skeletal system.
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66
Adding pins and plates to a fracture to aid repair is called traction.
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67
Red bone marrow is important in the production of new bone cells.
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