Deck 20: The Electron Transport Chain

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Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
The electron carrier _______________ is a derivative of quinone and has an isoprenoid tail.
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Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
The enzyme _______________ catalyzes the reduction of O2.
Question
Cytochrome c oxidase contains two heme A groups and three ________________ ions.
Question
________________ is an enzyme that scavenges H2O2 and converts it to molecular oxygen and water.
Question
________________ is/are the result of uncontrolled electron transfer to oxygen
Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
_______________ is the prosthetic group in Complex I that accepts electrons from NADH.
Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
The citric acid cycle enzyme _______________ is also part of an electron-transport complex.
Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
_______________ is an ATP-generating process in which an inorganic substance such as oxygen serves as the ultimate electron acceptor.
Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
_______________: The process by which cytoplasmic NADH can be oxidized by O2 using the electron-transport system.
Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
Another name for ubiquinone is ________________.
Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
The permeability of the outer mitochondrial membrane is primarily due to the presence of _______________.
Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
A strong oxidizing agent has a strong tendency to ________________ (accept, donate) electron(s).
Question
The transfer of a single electron to O2 forms the reactive ________________ ion.
Question
Complex IV is also known as ________________.
Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
_______________ is the complex with three Fe-sulfhydryl electron acceptors.
Question
________________ donates electrons to cytochrome C.
Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
The prosthetic group _______________ is present in complexes I, II, and III of electron transport.
Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
_______________ is where oxidative phosphorylation occurs in eukaryotes.
Question
________________ carries electrons from Complex III to Complex IV.
Question
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
Cytochrome ________________ is the only water-soluble cytochrome of the electron-transport chain.
Question
Choose the correct path taken by a pair of electrons as they travel down the electron-transport chain.

A) NADH → Complex I → CoQ → Complex III → Cytochrome c → Complex IV → O2
B) FADH2 → Complex I → CoQ → Complex III → Cytochrome c → Complex IV → O2
C) NADH → Complex I → Complex II→ Complex III → Cytochrome c → Complex IV → O2
D) FADH2 → Complex II → CoQ → Complex III → Cytochrome c → Complex IV → O2
E) A and D
Question
What pathologic condition(s) results from free-radical injury?

A) emphysema
B) Parkinson's disease
C) diabetes
D) atherogenesis
E) All of the above.
Question
What is this in reference to?
Question
What is a major defense strategy against oxidative damage caused by reactive oxygen species (ROS)?
Question
Which of the following does not participate in, nor is a component of, the electron-transport chain?

A) coenzyme A
B) nonheme, iron-sulfur proteins
C) coenzyme Q
D) cytochrome c1
E) NADH
Question
Which of the following does not pump protons?

A) Complex I
B) Complex II
C) Complex III
D) Complex IV
E) All of the above.
Question
In proteins, these amino acid residues usually complex to the iron-sulfur clusters.

A) glycine
B) arginine
C) cysteine
D) All of the above.
E) None of the above.
Question
Describe the role that Q takes as the NADH-Q oxidoreductase transfers electrons from NADH to coenzyme Q.
Question
Give the balanced equation for the net reaction catalyzed by Q-cytochrome c oxidoreducatase.
Question
To what extent is ATP recycled on a daily basis?

A) 50 ATPs per day
B) 300 ATPs per day
C) 1500 ATPs per day
D) 3000 ATPs per day
E) None of the above.
Question
What is a cytochrome?

A) a protein that transfers electrons and that also contains a heme prosthetic group
B) a chloroplast protein that transfers electrons and that also contains an iron-sulfur prosthetic group
C) a protein that pumps ATP and that also contains iron
D) All of the above.
E) None of the above.
Question
What are the mechanisms that a cell uses to protect against the production of oxygen radicals?
Question
Coenzyme Q is also called:

A) NADH.
B) oxidoreductase.
C) ubiquinone.
D) All of the above.
E) None of the above.
Question
Describe the path by which electrons from FADH2 enter the electron-transport chain.
Question
Explain why less ATP is made from the reoxidation of FADH2 compared to NADH.
Question
Electron flow down the electron-transport chain leads to:

A) the transport of protons across the inner mitochondrial membrane from inside the matrix to the intermembrane space.
B) the transport of protons across the inner mitochondrial membrane from the intermembrane space into the matrix.
C) the coupled synthesis of GTP.
D) a dangerous imbalance of K+ ions across the mitochondrial membrane.
E) None of the above.
Question
In the Rieske center, the iron-sulfur center is coordinated to the amino acid(s):

A) histidine
B) cysteine
C) histidine and cysteine
D) cysteine and methionine
E) None of the above.
Question
The Q cycle:

A) transfers electrons from a two-electron carrier to a one-electron carrier.
B) recycles protons.
C) acts as an NADH exchange with the cytosol.
D) A and B.
E) A, B and C.
Question
What is the "dead zone" in the Gulf of Mexico and how did it come into being?
Question
Calculate the ∆G°ʹ for the reaction where lactate + NAD+ is converted to pyruvate + NADH.
Question
What are the two half-reactions for the reduction of O2 by NADH?
Question
In which direction do electrons flow in the electron transport chain?
Question
What are the fully oxidized and fully reduced states of coenzyme Q and how are they related to transmembrane proton transport?
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Deck 20: The Electron Transport Chain
1
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
The electron carrier _______________ is a derivative of quinone and has an isoprenoid tail.
c
2
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
The enzyme _______________ catalyzes the reduction of O2.
j
3
Cytochrome c oxidase contains two heme A groups and three ________________ ions.
copper
4
________________ is an enzyme that scavenges H2O2 and converts it to molecular oxygen and water.
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k this deck
5
________________ is/are the result of uncontrolled electron transfer to oxygen
Unlock Deck
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k this deck
6
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
_______________ is the prosthetic group in Complex I that accepts electrons from NADH.
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k this deck
7
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
The citric acid cycle enzyme _______________ is also part of an electron-transport complex.
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Unlock for access to all 43 flashcards in this deck.
Unlock Deck
k this deck
8
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
_______________ is an ATP-generating process in which an inorganic substance such as oxygen serves as the ultimate electron acceptor.
Unlock Deck
Unlock for access to all 43 flashcards in this deck.
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k this deck
9
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
_______________: The process by which cytoplasmic NADH can be oxidized by O2 using the electron-transport system.
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Unlock Deck
k this deck
10
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
Another name for ubiquinone is ________________.
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k this deck
11
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
The permeability of the outer mitochondrial membrane is primarily due to the presence of _______________.
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k this deck
12
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
A strong oxidizing agent has a strong tendency to ________________ (accept, donate) electron(s).
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k this deck
13
The transfer of a single electron to O2 forms the reactive ________________ ion.
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k this deck
14
Complex IV is also known as ________________.
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15
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
_______________ is the complex with three Fe-sulfhydryl electron acceptors.
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k this deck
16
________________ donates electrons to cytochrome C.
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17
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
The prosthetic group _______________ is present in complexes I, II, and III of electron transport.
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Unlock Deck
k this deck
18
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
_______________ is where oxidative phosphorylation occurs in eukaryotes.
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k this deck
19
________________ carries electrons from Complex III to Complex IV.
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20
Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
a) mitochondria
b) ubiquinone
c) coenzyme Q
d) flavin mononucleotide (FMN)
e) iron-sulfur clusters
f) respiration
g) transporters
h) porins
i) succinate dehydrogenase
j) cytochrome c oxidase
k) Complex II
l) Complex III
Cytochrome ________________ is the only water-soluble cytochrome of the electron-transport chain.
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k this deck
21
Choose the correct path taken by a pair of electrons as they travel down the electron-transport chain.

A) NADH → Complex I → CoQ → Complex III → Cytochrome c → Complex IV → O2
B) FADH2 → Complex I → CoQ → Complex III → Cytochrome c → Complex IV → O2
C) NADH → Complex I → Complex II→ Complex III → Cytochrome c → Complex IV → O2
D) FADH2 → Complex II → CoQ → Complex III → Cytochrome c → Complex IV → O2
E) A and D
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22
What pathologic condition(s) results from free-radical injury?

A) emphysema
B) Parkinson's disease
C) diabetes
D) atherogenesis
E) All of the above.
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Unlock Deck
k this deck
23
What is this in reference to?
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24
What is a major defense strategy against oxidative damage caused by reactive oxygen species (ROS)?
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k this deck
25
Which of the following does not participate in, nor is a component of, the electron-transport chain?

A) coenzyme A
B) nonheme, iron-sulfur proteins
C) coenzyme Q
D) cytochrome c1
E) NADH
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26
Which of the following does not pump protons?

A) Complex I
B) Complex II
C) Complex III
D) Complex IV
E) All of the above.
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k this deck
27
In proteins, these amino acid residues usually complex to the iron-sulfur clusters.

A) glycine
B) arginine
C) cysteine
D) All of the above.
E) None of the above.
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28
Describe the role that Q takes as the NADH-Q oxidoreductase transfers electrons from NADH to coenzyme Q.
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29
Give the balanced equation for the net reaction catalyzed by Q-cytochrome c oxidoreducatase.
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30
To what extent is ATP recycled on a daily basis?

A) 50 ATPs per day
B) 300 ATPs per day
C) 1500 ATPs per day
D) 3000 ATPs per day
E) None of the above.
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Unlock for access to all 43 flashcards in this deck.
Unlock Deck
k this deck
31
What is a cytochrome?

A) a protein that transfers electrons and that also contains a heme prosthetic group
B) a chloroplast protein that transfers electrons and that also contains an iron-sulfur prosthetic group
C) a protein that pumps ATP and that also contains iron
D) All of the above.
E) None of the above.
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k this deck
32
What are the mechanisms that a cell uses to protect against the production of oxygen radicals?
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k this deck
33
Coenzyme Q is also called:

A) NADH.
B) oxidoreductase.
C) ubiquinone.
D) All of the above.
E) None of the above.
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Unlock Deck
k this deck
34
Describe the path by which electrons from FADH2 enter the electron-transport chain.
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35
Explain why less ATP is made from the reoxidation of FADH2 compared to NADH.
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k this deck
36
Electron flow down the electron-transport chain leads to:

A) the transport of protons across the inner mitochondrial membrane from inside the matrix to the intermembrane space.
B) the transport of protons across the inner mitochondrial membrane from the intermembrane space into the matrix.
C) the coupled synthesis of GTP.
D) a dangerous imbalance of K+ ions across the mitochondrial membrane.
E) None of the above.
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Unlock for access to all 43 flashcards in this deck.
Unlock Deck
k this deck
37
In the Rieske center, the iron-sulfur center is coordinated to the amino acid(s):

A) histidine
B) cysteine
C) histidine and cysteine
D) cysteine and methionine
E) None of the above.
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Unlock for access to all 43 flashcards in this deck.
Unlock Deck
k this deck
38
The Q cycle:

A) transfers electrons from a two-electron carrier to a one-electron carrier.
B) recycles protons.
C) acts as an NADH exchange with the cytosol.
D) A and B.
E) A, B and C.
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39
What is the "dead zone" in the Gulf of Mexico and how did it come into being?
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40
Calculate the ∆G°ʹ for the reaction where lactate + NAD+ is converted to pyruvate + NADH.
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41
What are the two half-reactions for the reduction of O2 by NADH?
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42
In which direction do electrons flow in the electron transport chain?
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43
What are the fully oxidized and fully reduced states of coenzyme Q and how are they related to transmembrane proton transport?
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