Exam 20: The Electron Transport Chain

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What are the fully oxidized and fully reduced states of coenzyme Q and how are they related to transmembrane proton transport?

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In the fully oxidized state, ubiquinone (Q), has two keto groups. The addition of electrons and protons generates ubiquinol (QH2), the fully reduced form. Therefore, electron transfer reactions are coupled to proton binding and release.

Explain why less ATP is made from the reoxidation of FADH2 compared to NADH.

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Complex II is not a proton pump. When electrons flow from FADH2 to oxygen, as catalyzed by Complex II, Complex III, and Complex IV, fewer protons are pumped out of the matrix as compared to NADH. Thus, fewer ATP molecules are ultimately made.

Cytochrome c oxidase contains two heme A groups and three ________________ ions.

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copper

A strong oxidizing agent has a strong tendency to ________________ (accept, donate) electron(s).

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Another name for ubiquinone is ________________.

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Which of the following does not participate in, nor is a component of, the electron-transport chain?

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What pathologic condition(s) results from free-radical injury?

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Which of the following does not pump protons?

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Complex IV is also known as ________________.

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Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is an ATP-generating process in which an inorganic substance such as oxygen serves as the ultimate electron acceptor.

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Cytochrome ________________ is the only water-soluble cytochrome of the electron-transport chain.

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What is a cytochrome?

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Choose the correct answer from the list below. Not all of the answers will be used. -The enzyme _______________ catalyzes the reduction of O2.

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To what extent is ATP recycled on a daily basis?

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________________ is an enzyme that scavenges H2O2 and converts it to molecular oxygen and water.

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What are the mechanisms that a cell uses to protect against the production of oxygen radicals?

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The Q cycle:

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Choose the correct path taken by a pair of electrons as they travel down the electron-transport chain.

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Choose the correct answer from the list below. Not all of the answers will be used. -_______________ is the complex with three Fe-sulfhydryl electron acceptors.

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Describe the role that Q takes as the NADH-Q oxidoreductase transfers electrons from NADH to coenzyme Q.

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