Multiple Choice
The first mechanistic step in the direct reaction of an amine with a carboxylic acid to produce an amide is ________.
A) an acid-base reaction
B) nucleophilic attack on the carbonyl carbon
C) loss of H2O
D) loss of CO2
E) loss of N2
Correct Answer:

Verified
Correct Answer:
Verified
Q50: What two alkenes, which contain only one
Q51: Provide the structure of the major organic
Q52: Show the deprotonation of benzoic acid by
Q53: Propose a reasonable synthetic route to prepare
Q54: Provide the major organic product of the
Q56: What compound is produced when (CH<sub>3</sub>)<sub>2</sub>CHCH<sub>2</sub>Br is
Q57: In glutaric acid (HOOCCH<sub>2</sub>CH<sub>2</sub>CH<sub>2</sub>COOH), pKa<sub>1</sub> is 4.35
Q58: Provide the structure of 3-nitrophthalic acid.
Q59: Carboxylic acids boil at considerably higher temperatures
Q60: The strongest dichlorobutanoic acid is _.<br>A) 2,2-dichlorobutanoic