Part of the Reason That Tricyclic Antidepressants (TCAs) Have Fallen

Multiple Choice

Part of the reason that tricyclic antidepressants (TCAs) have fallen somewhat out of favor compared with selective serotonin reuptake inhibitors (SSRIs) is because:

A) SSRIs have the added advantage of also blocking norepinephrine and dopamine.
B) TCA overdoses have a cardiotoxic effect.
C) SSRIs have the added advantage of also blocking histamine and acetylcholine.
D) TCA overdoses often create a hypertensive crisis in patients.