Endocrine Diseases Are Often Due to Loss of Hormone (I

Multiple Choice

Endocrine diseases are often due to loss of hormone (i.e.,a hormone deficiency) .Which of the following would cause an endocrine disease that mimicked a protein hormone deficiency without a deficiency in the levels of a circulating protein hormone?

A) Inactive prohormone convertase
B) Defective exocytotic machinery
C) Loss of blood transport proteins
D) Defective receptor
E) Null mutation in corresponding hormone gene