A 30-Year-Old Man Is Referred to a Gastroenterologist for Evaluation

Multiple Choice

A 30-year-old man is referred to a gastroenterologist for evaluation of persistent dyspepsia (indigestion) .He is noted to have other symptoms,including flushing and hypotension,and after a bone marrow biopsy,systemic mastocytosis (an excessive proliferation of histamine-containing mast cells) is diagnosed.An increased propensity for gastric and duodenal ulcers in this patient is probably ascribable to overproduction of which of the following second messengers in gastric parietal cells?

A) Calcium
B) Inositol trisphosphate
C) Diacyglycerol
D) Cyclic guanosine monophosphate (cGMP)
E) Cyclic adenosine monophosphate (cAMP)