How Does a Protein Kinase Cascade Amplify an Intercellular Signal

Multiple Choice

How does a protein kinase cascade amplify an intercellular signal?

A) Protein kinase molecules open cell junctions,amplifying the intercellular signal.
B) The activated G protein binds and activates a second protein,amplifying the signal.
C) Nitric oxide opens cell channels,which allows protein kinase molecules to move quickly from cell to cell.
D) Second messengers create shortcuts that create multiple cascades.
E) Sequential activation of protein kinases can lead to the activation of thousands of effector proteins.