Regarding Psychoactive Drugs

Multiple Choice

Regarding psychoactive drugs,

A) both the phenomenon of "tolerance" to and the symptoms of "withdrawal" from a psychoactive drug can be explained by the positive feedback effect of the drug on the production of the endogenous neurotransmitter/neuromodulator for which the drug is an agonist.
B) Only drugs that bind to endorphin/enkephalin receptors are described as "psychoactive."
C) use of psychoactive drugs may result in physical dependence upon them.
D) both "the phenomenon of 'tolerance' to and the symptoms of 'withdrawal' from a psychoactive drug can be explained by the positive feedback effect of the drug on the production of the endogenous neurotransmitter/neuromodulator for which the drug is an agonist" and "only drugs that bind to endorphin/enkephalin receptors are described as 'psychoactive'" are correct.
E) both "the phenomenon of 'tolerance' to and the symptoms of 'withdrawal' from a psychoactive drug can be explained by the positive feedback effect of the drug on the production of the endogenous neurotransmitter/neuromodulator for which the drug is an agonist" and "use of psychoactive drugs may result in physical dependence upon them" are correct.