What Is "Allosteric Modulation

Multiple Choice

What is "allosteric modulation"?

A) regulation of physiological functions by the sympathetic division of the autonomic nervous system
B) modification of the functional state of a protein by temperature or pH
C) the change in the shape and functional state of a protein that occurs when a ligand binds to a regulatory site
D) the fact that all binding sites on a protein must be occupied to have a biological effect
E) the ability of a single ligand-binding site to bind to molecularly similar ligands