What Stops Blood from Flowing Back into the Atrium from the Ventricle

Multiple Choice

What stops blood from flowing back into the atrium from the ventricle?

A) The two chambers are not connected.
B) The blood naturally will follow the path of least resistance.
C) The one-way valve located between the two compartments.
D) The pressure from the atrium keeps the blood in the ventricle.
E) Ventricular pressure is only directed to the systemic system.