Why Is a Person Who Has Inherited One Copy of a Harmful

Multiple Choice

Why is a person who has inherited one copy of a harmful BRCA allele much more likely to have early-onset breast cancer or ovarian cancer than a person with two functioning alleles?

A) Apoptosis is increased,as the tumor suppressors are not functioning.
B) Cell growth is accelerated,as oncogenes are switched on.
C) With the increase of BRCA protein,apoptosis is induced and cell death occurs.
D) Mutations accumulate as DNA repair is slowed and cell growth may accelerate.
E) Cells fail to enter apoptosis and eventually become a tumor.