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What Is One Major Limitation of Two-Dimensional Gel Electrophoresis (2-DGE)

Question 28

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What is one major limitation of two-dimensional gel electrophoresis (2-DGE) ?


A) It is extremely costly to execute in a typical molecular biology laboratory.
B) When products are separated, they tend to leach out of the gel matrix.
C) Only the most abundant products are detected.
D) 2-DGE can be run only on nucleic acids.
E) 2-DGE is useful only in separating eukaryotic gene products.

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