For the Patient's New Immune System to Function Effectively in Bone

Multiple Choice

For the patient's new immune system to function effectively in bone marrow recipients,some HLA allotypes must be shared because _____.(Select all that apply.)

A) professional antigen-presenting cells are host-derived
B) professional antigen-presenting cells are donor-derived
C) otherwise an autoimmune disease would develop
D) newly generated T cells are positively selected on the recipient's thymic epithelium
E) if all HLA molecules were mismatched,acute rejection of the grafted cells would occur.