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_____ in the Switch Regions Positioned 5′ to Each Heavy-Chain

Question 46

Multiple Choice

_____ in the switch regions positioned 5′ to each heavy-chain C gene is induced by _____.


A) Somatic hypermutation; TI antigens
B) Chromatin remodeling; B-cell co-receptor signaling
C) Recombination; survival signals received from follicular dendritic cells
D) Transcription; helper T-cell cytokines
E) Gene repression; apoptotic signals received from tingible body macrophages.

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