Essay
What are the roles of the following molecules in the signal transduction pathway leading from the T-cell receptor: (i)the CD3 complex; (ii)protein tyrosine kinase Lck; (iii)CD45; (iv)ZAP-70; (v)the ζ chain; (vi)inositol trisphosphate (IP3); (vii)calcineurin?
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(i)The CD3 subunits γ,δ,and ε associated...View Answer
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