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The Mechanisms Contributing to Peptide Editing Include Which of the Following

Question 33

Multiple Choice

The mechanisms contributing to peptide editing include which of the following? (Select all that apply.)


A) removal of amino acids from the amino-terminal end by endoplasmic reticulum aminopeptidase (ERAP)
B) cathepsin S-mediated cleavage of invariant chain
C) the participation of tapasin in finding a 'good fit' for class I heterodimers
D) recycling an MHC class I heterodimer if the peptide falls out of its peptide-binding groove
E) upregulation of HLA-DM by interferon-γ.

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