Peptides That Bind to a Particular MHC Isoform Usually Have

Multiple Choice

Peptides that bind to a particular MHC isoform usually have either the same or chemically similar amino acids at two to three key positions that hold the peptide tightly in the peptide-binding groove of the MHC molecule.These amino acids are called _____ and the combination of these key residues is known as its _____.

A) alleles; allotypes
B) anchor residues; peptide-binding motif
C) allotype; haplotypes
D) invariant chains; haplotypes
E) restriction residues; MHC allotype.