The Immunological Consequence of Severe Combined Immunodeficiency Disease (SCID)caused by a Genetic

Multiple Choice

The immunological consequence of severe combined immunodeficiency disease (SCID) caused by a genetic defect in either RAG-1 or RAG-2 genes is

A) lack of somatic recombination in T-cell receptor and immunoglobulin gene loci
B) lack of somatic recombination in T-cell receptor loci
C) lack of somatic recombination in immunoglobulin loci
D) lack of somatic hypermutation in T-cell receptor and immunoglobulin loci
E) lack of somatic hypermutation in T-cell receptor loci.