Purifying Selection Removes Harmful Alleles from the Population Because a Proportion

Essay

Purifying selection removes harmful alleles from the population because a proportion, at least, of people who carry the harmful alleles have reduced biological fitness (manifesting by reduced reproductive success rates). For any inherited disorder, the frequency of mutant alleles in the population is usually stable: mutant alleles that are eliminated from the population (because the people that have them do not reproduce, or reproduce less efficiently), and new mutant alleles are created by de novo mutation. Link individual types of single gene disorder
a) to
e) to one of the values i) to iv) for the percentage of mutant alleles that arise by de novo mutation.