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Essay

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Two important RNA processing events lead to specialized end sequences in most human mRNAs: ____1____ at the 5' end, and ____2____ at the 3' end. The altered sequences protect the RNA from attack by cellular ____3_____ and confer a measure of stability. In ____1____ the most distinctive change is a specialized end nucleotide, ____4_____ _____5______, that is joined to its neighbor using a distinctive ____6______ bond. In this case, the ____7____ carbon atom of the end nucleotide is joined to the ____7_____ carbon atom of its neighbor. In ____2______ a sequence of about 200 ____8____ is enzymatically added to the 3' end by a dedicated enzyme called _____9_____ ____10______.