Under What Circumstances Does Membrane Transport Always Require Energy

Multiple Choice

Under what circumstances does membrane transport always require energy?

A) whenever a molecule is polar and is moved through a phospholipid bilayer membrane
B) whenever a solute needs to be moved from low concentration to high concentration through a phospholipid bilayer membrane
C) whenever a solute is charged, such as an ion, and is moved through a phospholipid bilayer membrane
D) whenever molecules are moved that are too large to pass through the phospholipid bilayer membrane