Kawakubo's Group Created a Glycoprotein with a Terminal NAG I

Multiple Choice

Kawakubo's group created a glycoprotein with a terminal NAG i.e., a protein with NAG attached to its end) . Their hypothesis is that the terminal NAG-and not the protein component-is responsible for the damage to the cell wall in H. pylori. What would be the most appropriate control for testing this hypothesis?

A) Grow H. pylori in a test tube with glycoprotein that has its terminal NAG removed.
B) Destroy the H. pylori by exposing them to a hypotonic solution. Then add the glycoprotein and observe.
C) Expose other species of bacteria to the glycoprotein.
D) Grow H. pylori in a test tube in vitro) with no glycoprotein.