Unequal Crossing Over During Prophase I Can Result in One

Multiple Choice

Unequal crossing over during prophase I can result in one sister chromosome with a deletion and another with a duplication. A mutated form of hemoglobin, so- called hemoglobin Lepore, exists in the human population. Hemoglobin Lepore has a deleted series of amino acids. If this mutated form was caused by unequal crossing over, what would be an expected consequence?

A) Each of the genes in the hemoglobin gene family must show the same deletion.
B) The deleted gene must have undergone exon shuffling.
C) If it is still maintained in the human population, hemoglobin Lepore must be selected for in evolution.
D) The deleted region must be located in a different area of the individual's genome.
E) There should also be persons whose hemoglobin contains two copies of the series of amino acids that is deleted in hemoglobin Lepore.